Neurophysiological Investigation of Spontaneous Correlated and Anticorrelated Fluctuations of the BOLD Signal

• Published in: The Journal of neuroscience Vol. 33; no. 15; pp. 6333 - 6342
• Main Authors: Keller, Corey J., Bickel, Stephan, Honey, Christopher J., Groppe, David M., Entz, Laszlo, Craddock, R. Cameron, Lado, Fred A., Kelly, Clare, Milham, Michael, Mehta, Ashesh D.
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 10.04.2013
• Subjects: Adult; Brain Mapping - methods; Brain Mapping - statistics & numerical data; Brain Waves - physiology; Cerebral Cortex - blood supply; Cerebral Cortex - physiology; Electrodes, Implanted; Electroencephalography - methods; Electroencephalography - statistics & numerical data; Female; Humans; Image Interpretation, Computer-Assisted - methods; Magnetic Resonance Imaging - methods; Magnetic Resonance Imaging - statistics & numerical data; Male; Neural Pathways - physiology; Neurons - physiology; Neurophysiology - methods; ROC Curve

Analyses of intrinsic fMRI BOLD signal fluctuations reliably reveal correlated and anticorrelated functional networks in the brain. Because the BOLD signal is an indirect measure of neuronal activity and anticorrelations can be introduced by preprocessing steps, such as global signal regression, the...