History and Future Perspectives on the Discipline of Quantitative Systems Pharmacology Modeling and Its Applications

• Published in: Frontiers in physiology Vol. 12; p. 637999
• Main Authors: Azer, Karim, Kaddi, Chanchala D, Barrett, Jeffrey S, Bai, Jane P F, McQuade, Sean T, Merrill, Nathaniel J, Piccoli, Benedetto, Neves-Zaph, Susana, Marchetti, Luca, Lombardo, Rosario, Parolo, Silvia, Immanuel, Selva Rupa Christinal, Baliga, Nitin S
• Format: Journal Article
• Language: English
• Published: Switzerland Frontiers Media S.A 25.03.2021
• Subjects: bioinformatics; computational biology; data science; Physiology; QSP modeling; systems biology; systems pharmacology; computational biology; systems biology; data science; bioinformatics; drug development; systems pharmacology; QSP modeling

Mathematical biology and pharmacology models have a long and rich history in the fields of medicine and physiology, impacting our understanding of disease mechanisms and the development of novel therapeutics. With an increased focus on the pharmacology application of system models and the advances i...