Maternal serum cytokine levels and risk of bipolar disorder

• Published in: Brain, behavior, and immunity Vol. 63; pp. 108 - 114
• Main Authors: Cheslack-Postava, Keely, Cremers, Serge, Bao, Yuanyuan, Shen, Ling, Schaefer, Catherine A., Brown, Alan S.
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Inc 01.07.2017
• Subjects: Allergy and Immunology; Bipolar disorder; Bipolar Disorder - immunology; Case-Control Studies; Cohort Studies; Cytokines; Cytokines - blood; Female; Humans; IL-4; IL-6; Immune; Influenza, Human - complications; Interleukin-4 - blood; Interleukin-6 - blood; Maternal; Pregnancy; Pregnancy Complications, Infectious - immunology; Prenatal; Prenatal Exposure Delayed Effects; Psychiatry; Risk Factors; Prenatal; Maternal; Cytokines; Immune; IL-4; Bipolar disorder; IL-6

•Cases with bipolar disorder (BD) and matched controls were identified.•Nine cytokines were measured in archived prenatal maternal serum samples.•Among cases overall, the cytokine levels were not associated with risk of BD.•Lower levels of IL-4 and IL-6 were observed in BD cases without psychotic fe...