Corticosteroid-Dependent Plasticity Mediates Compulsive Alcohol Drinking in Rats - Vendruscolo, Leandro F.; Barbier, Estelle; Schlosburg, Joel E.; Misra, Kaushik K.; Whitfield, Timothy W.; Logrip, Marian L.; Rivier, Catherine; Repunte-Canonigo, Vez; Zorrilla, Eric P.; Sanna, Pietro P.; Heilig, Markus; Koob, George F. (The Journal of neuroscience, 2012)
Keywords: Alcohol Drinking - drug therapy; Alcohol Drinking - metabolism; Alcohol Drinking - pathology; Analysis of Variance; Animals; Behavior, Addictive - drug therapy; Behavior, Addictive - metabolism; Brain - metabolism; Central Nervous System Depressants - administration & dosage; Compulsive Behavior - physiopathology; Conditioning, Operant - drug effects; Ethanol - administration & dosage; Hormone Antagonists - therapeutic use; Male; Mifepristone - therapeutic use; Rats; Rats, Wistar; Receptors, Glucocorticoid - genetics; Receptors, Glucocorticoid - metabolism; Receptors, Mineralocorticoid - genetics; Receptors, Mineralocorticoid - metabolism; Reinforcement Schedule; RNA, Messenger - metabolism; Self Administration; Substance Withdrawal Syndrome - drug therapy; Substance Withdrawal Syndrome - metabolism; Up-Regulation - drug effects