Design, Synthesis and Biological Activity Evaluation of β-Carboline Derivatives Containing Nitrogen Heterocycles - Wu, Guiyun; Wang, Wenhang; Li, Fulian; Xu, Chenlu; Zhou, Yue; Li, Zhurui; Liu, Bingqian; Shao, Lihui; Chen, Danping; Bai, Song; Wang, Zhenchao (Molecules (Basel, Switzerland), 2024)
Keywords: Antineoplastic Agents - chemical synthesis; Antineoplastic Agents - chemistry; Antineoplastic Agents - pharmacology; antitumor; Apoptosis; Apoptosis - drug effects; Biological activity; Cancer therapies; Carbolines - chemical synthesis; Carbolines - chemistry; Carbolines - pharmacology; Cell adhesion & migration; Cell cycle; Cell growth; Cell Line, Tumor; Cell Movement - drug effects; Cell Proliferation - drug effects; Cyclin-dependent kinases; Drug Design; Drug development; Drug Screening Assays, Antitumor; Heterocyclic Compounds - chemical synthesis; Heterocyclic Compounds - chemistry; Heterocyclic Compounds - pharmacology; Humans; Kinases; Molecular Structure; Motility; Natural products; Nitrogen; Nitrogen - chemistry; PC-3 Cells; Phase transitions; Raltegravir; Reactive oxygen species; Reactive Oxygen Species - metabolism; ROS; Structure-Activity Relationship; β-carboline derivatives; apoptosis; antitumor; cell cycle; β-carboline derivatives; ROS