Barx2, a New Homeobox Gene of the Bar Class, is Expressed in Neural and Craniofacial Structures during Development

• Published in: Proceedings of the National Academy of Sciences - PNAS Vol. 94; no. 6; pp. 2632 - 2637
• Main Authors: Jones, Frederick S., Kioussi, Chrissa, Copertino, Donald W., Kallunki, Pekka, Holst, Brent D., Edelman, Gerald M.
• Format: Journal Article
• Language: English
• Published: United States National Academy of Sciences of the United States of America 18.03.1997; National Acad Sciences; National Academy of Sciences; The National Academy of Sciences of the USA
• Subjects: Amino Acid Sequence; Animals; Base Sequence; Biological Sciences; Cloning, Molecular; Complementary DNA; DNA; Drosophila; Drosophila melanogaster; Embryonic and Fetal Development; Embryos; Facial Bones - embryology; Gene expression regulation; Gene Expression Regulation, Developmental; Genes; Genes, Homeobox; Genetic screening; Homeobox genes; Homeodomain proteins; Homeodomain Proteins - biosynthesis; Homeodomain Proteins - chemistry; Homeodomain Proteins - genetics; In Situ Hybridization; Mice; Molecular Sequence Data; Morphogenesis; Nervous System - embryology; Nervous System - metabolism; Physical growth; Protein Structure, Secondary; Proteins; Recombinant Fusion Proteins - biosynthesis; RNA, Messenger - biosynthesis; Sequence Homology, Amino Acid; Skull - embryology; Telencephalon; Transcription Factors - chemistry

Homeobox genes are regulators of place-dependent morphogenesis and play important roles in controlling the expression patterns of cell adhesion molecules (CAMs). To identify proteins that bind to a regulatory element common to the genes for two neural CAMs, Ng--CAM and L1, we screened a mouse cDNA e...