How Local Excitation-Inhibition Ratio Impacts the Whole Brain Dynamics

• Published in: The Journal of neuroscience Vol. 34; no. 23; pp. 7886 - 7898
• Main Authors: Deco, G., Ponce-Alvarez, A., Hagmann, P., Romani, G. L., Mantini, D., Corbetta, M.
• Format: Journal Article
• Language: English
• Published: United States Society for Neuroscience 04.06.2014
• Subjects: Action Potentials - physiology; Brain - cytology; Brain - physiology; Computer Simulation; Entropy; Feedback, Physiological - physiology; Humans; Models, Neurological; Nerve Net - physiology; Neural Inhibition - physiology; Neural Pathways - physiology; Neurons - physiology; Nonlinear Dynamics; anatomical connectivity; resting-state activity; functional connectivity; local feedback inhibition; large-scale brain model

The spontaneous activity of the brain shows different features at different scales. On one hand, neuroimaging studies show that long-range correlations are highly structured in spatiotemporal patterns, known as resting-state networks, on the other hand, neurophysiological reports show that short-ran...