Enolase 1 differentially contributes to cell transformation in lung cancer but not in esophageal cancer

• Published in: Oncology letters Vol. 19; no. 4; pp. 3189 - 3196
• Main Authors: Chen, Jo‑Mei, Chiu, Shao‑Chih, Chen, Kun‑Chieh, Huang, Yun‑Ru, Liao, Yu‑Ting, Yu, Chang‑Tze
• Format: Journal Article
• Language: English
• Published: Greece Spandidos Publications 01.04.2020; Spandidos Publications UK Ltd; D.A. Spandidos
• Subjects: Age; Analysis; Aprotinin; Biotechnology; Cancer; Cell cycle; Cell growth; Cyclin-dependent kinases; EDTA; Esophageal cancer; Gastric cancer; Immunoglobulins; Kidney cancer; Kinases; Liver cancer; Lung cancer; Medical prognosis; Membranes; Oncology; Pancreatic cancer; Patients; Penicillin; Plasmids; Proteins; Retina; Retinoblastoma; Scientific equipment industry; Statistical analysis; Stomach cancer; United States; Taiwan; lung cancer; enolase 1; cyclin-dependent kinase 6; esophageal cancer; p38; protein kinase B

Enolase transforms 2-phospho-D-glycerate into phosphoenolpyruvate during glycolysis. The human enolase (ENO) family comprises three members named ENO3, which is restricted to muscle tissues, ENO2, which is neuron- and neuroendocrine tissue-specific, and ENO1, which is expressed in almost all tissues...