Coxsackievirus A6 U.K. Genetic and Clinical Epidemiology Pre- and Post-SARS-CoV-2 Emergence

• Published in: Pathogens (Basel) Vol. 13; no. 11; p. 1020
• Main Authors: Joyce, Alice M., Hill, Jack D., Tsoleridis, Theocharis, Astbury, Stuart, Berry, Louise, Howson-Wells, Hannah C., Allen, Nancy, Canning, Ben, Jones, Carl B., Clark, Gemma, Irving, William L., Tarr, Alexander W., McClure, C. Patrick
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.11.2024; MDPI
• Subjects: Adolescent; Adult; Child; Child, Preschool; COVID-19; COVID-19 - epidemiology; COVID-19 - transmission; COVID-19 - virology; Coxsackievirus; coxsackievirus A6; Coxsackievirus infections; Coxsackieviruses; CVA6; Disease transmission; enterovirus; Enterovirus - genetics; Enterovirus - isolation & purification; Enterovirus A, Human - genetics; Enterovirus A, Human - isolation & purification; Epidemics; Epidemiology; Female; Foot-and-mouth disease; Gene sequencing; genetic epidemiology; Genetic relationship; Genomes; Hand, Foot and Mouth Disease - epidemiology; Hand, Foot and Mouth Disease - transmission; Hand, Foot and Mouth Disease - virology; Hand-foot-and-mouth disease; Health aspects; HFMD; Humans; Infant; Infections; Male; Medical research; Medicine, Experimental; Meningitis; Middle Aged; Mortality; Nucleic acids; Pandemics; Phylogenetics; Phylogeny; Retrospective Studies; SARS-CoV-2 - genetics; Severe acute respiratory syndrome coronavirus 2; Skin; Statistical analysis; Surveillance; Viral diseases; VP1 protein; Young Adult; United Kingdom; Europe; Japan; China; United Kingdom > UK; hand, foot and mouth disease; HFMD; enterovirus; coxsackievirus A6; CVA6; genetic epidemiology
• ISSN: 2076-0817; 2076-0817
• DOI: 10.3390/pathogens13111020

Coxsackievirus A6 (CVA6) has become increasingly clinically relevant as a cause of Hand, Foot and Mouth Disease (HFMD) globally since 2008. However, most laboratories do not routinely determine the enteroviral type of positive samples. The non-pharmaceutical measures introduced to curb transmission...