National Trends in Oral Anticoagulant Use in the United States, 2007 to 2011

• Published in: Circulation Cardiovascular quality and outcomes Vol. 5; no. 5; pp. 615 - 621
• Main Authors: Kirley, Kate, Qato, Dima M., Kornfield, Rachel, Stafford, Randall S., Alexander, G. Caleb
• Format: Journal Article
• Language: English
• Published: Hagerstown, MD Lippincott Williams & Wilkins 01.09.2012
• Subjects: Administration, Oral; Aged; Aged, 80 and over; Ambulatory Care - trends; Anticoagulants - administration & dosage; Anticoagulants - economics; Antithrombins - administration & dosage; Antithrombins - economics; Atrial Fibrillation - drug therapy; Atrial Fibrillation - economics; Atrial Fibrillation - epidemiology; Benzimidazoles - administration & dosage; beta-Alanine - administration & dosage; beta-Alanine - analogs & derivatives; Biological and medical sciences; Blood. Blood coagulation. Reticuloendothelial system; Dabigatran; Drug Costs; Drug Prescriptions - statistics & numerical data; Drug Utilization - trends; Drug Utilization Review; Guideline Adherence - trends; Health Care Surveys; Health Expenditures; Humans; Medical Audit; Medical sciences; Middle Aged; Off-Label Use - statistics & numerical data; Pharmacology. Drug treatments; Practice Guidelines as Topic; Practice Patterns, Physicians' - economics; Practice Patterns, Physicians' - trends; Preventive Health Services - economics; Preventive Health Services - trends; Thromboembolism - economics; Thromboembolism - epidemiology; Thromboembolism - prevention & control; Time Factors; United States - epidemiology; Warfarin - administration & dosage; United States; North America; America; Chemotherapy; Treatment; Use; coumarins; Trend; anticoagulants; Anticoagulant; Coumarin; other anticoagulants

Little is known regarding the adoption of direct thrombin inhibitors in clinical practice. We examine trends in oral anticoagulation for the prevention of thromboembolism in the United States. We used the IMS Health National Disease and Therapeutic Index, a nationally representative audit of office-...