Arabidopsis thaliana sulfiredoxin is a plastidic cysteine-sulfinic acid reductase involved in the photooxidative stress response

• Published in: The Plant journal : for cell and molecular biology Vol. 49; no. 3; pp. 505 - 514
• Main Authors: Rey, Pascal, Bécuwe, Noëlle, Barrault, Marie-Bénédicte, Rumeau, Dominique, Havaux, Michel, Biteau, Benoît, Toledano, Michel B
• Format: Journal Article
• Language: English
• Published: Oxford, UK Oxford, UK : Blackwell Publishing Ltd 01.02.2007; Blackwell Publishing Ltd; Blackwell Science; Wiley
• Subjects: Adaptation, Physiological; Amino Acid Sequence; Antioxidants; Arabidopsis; Arabidopsis - enzymology; Arabidopsis Proteins; Arabidopsis Proteins - metabolism; Arabidopsis thaliana; Bacterial plant pathogens; Biological and medical sciences; Botany; Catalysis; catalytic activity; chloroplast; chloroplasts; Chloroplasts - enzymology; cysteine; cysteine-sulfinic acid; enzymes; enzymology; Fundamental and applied biological sciences. Psychology; Gene Expression; genes; Homozygote; Inactivation; Life Sciences; Light; Low temperature; Mammals; metabolism; Molecular Sequence Data; Mutagenesis, Insertional; mutants; Mutation; Oxidation; Oxidation-Reduction; Oxidative stress; Oxidoreductases Acting on Sulfur Group Donors; Oxidoreductases Acting on Sulfur Group Donors - metabolism; Pathology. Damages, economic importance; Peroxidases; Peroxidases - metabolism; peroxides; peroxiredoxin; Peroxiredoxins; Phenotype; photooxidative stress; Phytopathology. Animal pests. Plant and forest protection; Plant physiology and development; plant response; Sequence Homology, Amino Acid; stress response; sulfiredoxin; Temperature; Vegetal Biology; Water and solutes. Absorption, translocation and permeability; Yeasts; Oxidative stress; peroxiredoxin; Cysteine; Tolerance; cysteine-sulfinic acid; Antioxidant; Arabidopsis thaliana; sulfiredoxin; Gene; Cruciferae; Dicotyledones; Angiospermae; Spermatophyta; Mutation; Chloroplast; Low temperature; photooxidative stress
• ISSN: 0960-7412; 1365-313X
• DOI: 10.1111/j.1365-313X.2006.02969.x

The 2-cysteine peroxiredoxins (2-Cys-Prxs) are antioxidants that reduce peroxides through a thiol-based mechanism. During catalysis, these ubiquitous enzymes are occasionally inactivated by the substrate-dependent oxidation of the catalytic cysteine to the sulfinic acid (-SO₂H) form, and are reactiv...