Infection with the dengue RNA virus activates TLR9 signaling in human dendritic cells - Lai, Jenn‐Haung; Wang, Mei‐Yi; Huang, Chuan‐Yueh; Wu, Chien‐Hsiang; Hung, Li‐Feng; Yang, Chia‐Ying; Ke, Po‐Yuan; Luo, Shue‐Fen; Liu, Shih‐Jen; Ho, Ling‐Jun (EMBO reports, 2018)
Keywords: Activation; AMP; Animals; Bone marrow; Cyclic GMP; Cytosol; Cytosol - metabolism; dendritic cell; Dendritic cells; Dendritic Cells - metabolism; Dendritic Cells - pathology; Dendritic Cells - virology; Dendritic structure; Dengue - metabolism; Dengue - pathology; Dengue - virology; Dengue fever; dengue virus; Dengue Virus - physiology; Deoxyribonucleic acid; DNA; DNA, Mitochondrial - genetics; DNA-Binding Proteins - metabolism; EMBO23; EMBO37; Endodeoxyribonucleases - metabolism; Extracellular Space - metabolism; Gene Knockdown Techniques; Humans; Immune response; Immune system; Infections; Inflammasomes; Inflammasomes - metabolism; Interferon; Interferons - genetics; Interferons - metabolism; Membrane permeability; Mice; Mice, Knockout; Mitochondria; Mitochondria - metabolism; Mitochondrial DNA; Mitochondrial permeability transition pore; Mitochondrial Proteins - metabolism; Oxidation-Reduction; Permeability; Phosphorylation; Pores; Proteins; Reactive oxygen species; Reactive Oxygen Species - metabolism; Receptors; Ribonucleic acid; RNA; RNA viruses; RNA, Messenger - genetics; RNA, Messenger - metabolism; RNA, Small Interfering - metabolism; RNA, Viral - metabolism; Rodents; Signal Transduction; Signaling; TLR9; TLR9 protein; Toll-Like Receptor 9 - metabolism; Toll-like receptors; Transcription Factors - metabolism; Vector-borne diseases; Viral diseases; Viruses; TLR9; immune response; mitochondrial DNA; dendritic cell; dengue virus