Vascular Endothelial Cells and Innate Immunity

• Published in: Arteriosclerosis, thrombosis, and vascular biology Vol. 40; no. 6; pp. e138 - e152
• Main Authors: Shao, Ying, Saredy, Jason, Yang, William Y., Sun, Yu, Lu, Yifan, Saaoud, Fatma, Drummer, Charles, Johnson, Candice, Xu, Keman, Jiang, Xiaohua, Wang, Hong, Yang, Xiaofeng
• Format: Journal Article
• Language: English
• Published: United States American Heart Association, Inc 01.06.2020
• Subjects: Antigen Presentation; Arteriosclerosis - immunology; Cardiovascular System - immunology; Cytokines - metabolism; Endothelial Cells - immunology; Humans; Immune Tolerance; Immunity, Innate - immunology; Immunologic Memory; Inflammation - immunology; Macrophages - immunology; Obesity, Abdominal; Receptors, Cytoplasmic and Nuclear; Signal Transduction; Thrombosis - immunology; homeostasis; vascular inflammation; endothelial cells; cytokines; immunity, innate

In addition to the roles of endothelial cells (ECs) in physiological processes, ECs actively participate in both innate and adaptive immune responses. We previously reported that, in comparison to macrophages, a prototypic innate immune cell type, ECs have many innate immune functions that macrophag...