A Rapamycin-Sensitive Signaling Pathway Is Essential for the Full Expression of Persistent Pain States - Geranton, Sandrine M; Jimenez-Diaz, Lydia; Torsney, Carole; Tochiki, Keri K; Stuart, Sarah A; Leith, J. Lianne; Lumb, Bridget M; Hunt, Stephen P (The Journal of neuroscience, 2009)
Keywords: Afferent Pathways - cytology; Afferent Pathways - drug effects; Afferent Pathways - metabolism; Animals; Hyperalgesia - metabolism; Hyperalgesia - physiopathology; Immunosuppressive Agents - pharmacology; Male; Nerve Fibers, Myelinated - physiology; Nerve Fibers, Myelinated - ultrastructure; Nociceptors - cytology; Nociceptors - drug effects; Nociceptors - metabolism; Pain - metabolism; Pain - physiopathology; Pain Measurement; Pain Threshold - drug effects; Pain Threshold - physiology; Peripheral Nervous System Diseases - metabolism; Peripheral Nervous System Diseases - physiopathology; Posterior Horn Cells - cytology; Posterior Horn Cells - drug effects; Posterior Horn Cells - metabolism; Protein Kinases - metabolism; Rats; Rats, Sprague-Dawley; Rats, Wistar; Sciatic Neuropathy - metabolism; Sciatic Neuropathy - physiopathology; Sirolimus - pharmacology; Spinal Nerve Roots - cytology; Spinal Nerve Roots - drug effects; Spinal Nerve Roots - metabolism; Spinothalamic Tracts - physiology; TOR Serine-Threonine Kinases