Mesenchymal stem cell treatment improves outcome of COVID-19 patients via multiple immunomodulatory mechanisms - Zhu, Rongjia; Yan, Tingdong; Feng, Yingmei; Liu, Yan; Cao, Hongcui; Peng, Gongxin; Yang, Yanlei; Xu, Zhen; Liu, Jingqi; Hou, Wei; Wang, Xiaoyue; Li, Zhe; et al. (Cell research, 2021)
Keywords: 13/1; 13/100; 13/21; 13/31; 13/51; 38; 38/39; 45; 631/532/2074; 631/80/304; Adverse events; Aged; Animals; Antibodies; Antibodies, Viral - blood; B-Lymphocyte Subsets - cytology; B-Lymphocyte Subsets - immunology; B-Lymphocyte Subsets - metabolism; Biomedical and Life Sciences; C-reactive protein; C-Reactive Protein - analysis; CD28 antigen; Cell Biology; Chemotaxis; Clinical trials; Coronaviruses; COVID-19; COVID-19 - immunology; COVID-19 - therapy; COVID-19 - virology; CX3CR1 protein; Cytokines; Cytokines - genetics; Cytokines - metabolism; Cytoskeletal Proteins - metabolism; Disease Models, Animal; Extracellular Traps - metabolism; Female; Gene sequencing; Health services; Hematopoietic stem cells; Homeostasis; Humans; Immune system; Immunomodulation; Immunomodulators; In vivo methods and tests; Inflammation; L-selectin; Leukocytes (neutrophilic); Leukocytes, Mononuclear - cytology; Leukocytes, Mononuclear - metabolism; Life Sciences; Lymphocytes; Lymphocytes T; Maintenance; Male; Mesenchymal Stem Cell Transplantation; Mesenchymal stem cells; Mice; Mice, Inbred C57BL; Middle Aged; Patients; Peripheral blood; Placebos; Remission; SARS-CoV-2 - isolation & purification; Severe acute respiratory syndrome coronavirus 2; Signs and symptoms; Stem cell transplantation; Stem cells; T-Lymphocytes - cytology; T-Lymphocytes - immunology; T-Lymphocytes - metabolism; Thromboembolism; Thrombosis; Umbilical cord; Venous Thrombosis - metabolism; Venous Thrombosis - pathology; Viral diseases