Italian Clinical Practice Guidelines on Cholangiocarcinoma – Part I: Classification, diagnosis and staging

Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive increase in CCA incidence and mortality registered worldwide in the last two decades and the need to clarify various aspects of clinical man...

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Published inDigestive and liver disease Vol. 52; no. 11; pp. 1282 - 1293
Main Authors Alvaro, Domenico, Hassan, Cesare, Cardinale, Vincenzo, Carpino, Guido, Fabris, Luca, Gringeri, Enrico, Granata, Vincenza, Mutignani, Massimiliano, Morement, Helen, Giuliante, Felice, Guglielmi, Alfredo, Ridola, Lorenzo, Marzioni, Marco, Grazi, Gianluca, Guido, Maria, Giulio, Emilio Di, Tonini, Giuseppe, Pantano, Francesco, Venere, Rosanna, Bragazzi, Maria Consiglia, Biancanello, Francesca, Faccioli, Jessica, Giannetti, Aurora, Cintolo, Marcello, Giunta, Michela Di, Gambato, Martina, Lasagni, Alberto, Izzo, Francesco, Avallone, Antonio, Banales, Jesus, Rossi, Massimo, Catalano, Carlo, Laghi, Andrea, D'amati, Giulia, Mancino, Maria Grazia
Format Journal Article
LanguageEnglish
Published Netherlands Elsevier Ltd 01.11.2020
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Abstract Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive increase in CCA incidence and mortality registered worldwide in the last two decades and the need to clarify various aspects of clinical management have prompted the Italian Association for the Study of the Liver (AISF) to commission the drafting of dedicated guidelines in collaboration with a group of Italian scientific societies. These guidelines have been formulated in accordance with the Italian National Institute of Health indications and developed by following the GRADE method and related advancements.
AbstractList Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive increase in CCA incidence and mortality registered worldwide in the last two decades and the need to clarify various aspects of clinical management have prompted the Italian Association for the Study of the Liver (AISF) to commission the drafting of dedicated guidelines in collaboration with a group of Italian scientific societies. These guidelines have been formulated in accordance with the Italian National Institute of Health indications and developed by following the GRADE method and related advancements.
Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive increase in CCA incidence and mortality registered worldwide in the last two decades and the need to clarify various aspects of clinical management have prompted the Italian Association for the Study of the Liver (AISF) to commission the drafting of dedicated guidelines in collaboration with a group of Italian scientific societies. These guidelines have been formulated in accordance with the Italian National Institute of Health indications and developed by following the GRADE method and related advancements.Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive increase in CCA incidence and mortality registered worldwide in the last two decades and the need to clarify various aspects of clinical management have prompted the Italian Association for the Study of the Liver (AISF) to commission the drafting of dedicated guidelines in collaboration with a group of Italian scientific societies. These guidelines have been formulated in accordance with the Italian National Institute of Health indications and developed by following the GRADE method and related advancements.
Author Gringeri, Enrico
Alvaro, Domenico
Izzo, Francesco
Morement, Helen
Ridola, Lorenzo
Fabris, Luca
Gambato, Martina
Granata, Vincenza
Rossi, Massimo
Catalano, Carlo
Cardinale, Vincenzo
Giulio, Emilio Di
Giuliante, Felice
Carpino, Guido
Faccioli, Jessica
Avallone, Antonio
Laghi, Andrea
Giunta, Michela Di
Grazi, Gianluca
Mutignani, Massimiliano
Guglielmi, Alfredo
Guido, Maria
Tonini, Giuseppe
Cintolo, Marcello
Biancanello, Francesca
D'amati, Giulia
Pantano, Francesco
Marzioni, Marco
Bragazzi, Maria Consiglia
Venere, Rosanna
Banales, Jesus
Mancino, Maria Grazia
Hassan, Cesare
Giannetti, Aurora
Lasagni, Alberto
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BackLink https://www.ncbi.nlm.nih.gov/pubmed/32893173$$D View this record in MEDLINE/PubMed
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ContentType Journal Article
Contributor Gringeri, Enrico
Alvaro, Domenico
Izzo, Francesco
Morement, Helen
Ridola, Lorenzo
Fabris, Luca
Gambato, Martina
Granata, Vincenza
Rossi, Massimo
Catalano, Carlo
Cardinale, Vincenzo
Giulio, Emilio Di
Giuliante, Felice
Carpino, Guido
Faccioli, Jessica
Avallone, Antonio
Laghi, Andrea
Giunta, Michela Di
Grazi, Gianluca
Mutignani, Massimiliano
Guglielmi, Alfredo
Guido, Maria
Tonini, Giuseppe
Cintolo, Marcello
Biancanello, Francesca
D'amati, Giulia
Pantano, Francesco
Marzioni, Marco
Bragazzi, Maria Consiglia
Venere, Rosanna
Banales, Jesus
Mancino, Maria Grazia
Hassan, Cesare
Giannetti, Aurora
Lasagni, Alberto
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  givenname: Felice
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  organization: Department of Translational and Precision Medicine, "Sapienza" University of Rome, Rome, Italy
– sequence: 20
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  fullname: Bragazzi, Maria Consiglia
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  fullname: Biancanello, Francesca
  organization: Department of Medical-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Rome, Italy
– sequence: 22
  givenname: Jessica
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  fullname: Faccioli, Jessica
  organization: Department of Translational and Precision Medicine, "Sapienza" University of Rome, Rome, Italy
– sequence: 23
  givenname: Aurora
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  fullname: Giannetti, Aurora
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  givenname: Marcello
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  fullname: Cintolo, Marcello
  organization: Digestive Endoscopy Unit, ASST Niguarda, Milan, Italy
– sequence: 25
  givenname: Michela Di
  surname: Giunta
  fullname: Giunta, Michela Di
  organization: Hepatobiliary Surgery and Liver Transplantation Unit, Department of Surgery Oncology and Gastroenterology, DISCOG, Padova, Italy
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  surname: Gambato
  fullname: Gambato, Martina
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– sequence: 27
  givenname: Alberto
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  fullname: Lasagni, Alberto
  organization: Department of Molecular Medicine, Azienda Ospedaliera/Università di Padova, Italy
– sequence: 28
  givenname: Francesco
  surname: Izzo
  fullname: Izzo, Francesco
  organization: Division of Hepatobiliary Surgery, Istituto Nazionale dei Tumori, IRCCS, Fondazione Pascale, Naples, Italy
– sequence: 29
  givenname: Antonio
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  fullname: Avallone, Antonio
  organization: Division of Abdominal Oncology, Istituto Nazionale dei Tumori, IRCCS, Fondazione Pascale, Naples, Italy
– sequence: 30
  givenname: Jesus
  surname: Banales
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  organization: Department of Liver and Gastrointestinal Diseases, Biodonostia Research Institute - Donostia University Hospital, University of the Basque Country (UPV/EHU), San Sebastian, Spain
– sequence: 31
  givenname: Massimo
  surname: Rossi
  fullname: Rossi, Massimo
  organization: Hepato-bilio-pancreatic and Liver Transplant Unit, Department of Surgery, "Sapienza" University of Rome, Italy
– sequence: 32
  givenname: Carlo
  surname: Catalano
  fullname: Catalano, Carlo
  organization: Department of Radiological, Oncological and Anatomopathological Sciences, "Sapienza" University of Rome, Rome, Italy
– sequence: 33
  givenname: Andrea
  surname: Laghi
  fullname: Laghi, Andrea
  organization: Department of Medical-Surgical Sciences and Translational Medicine, "Sapienza" University of Rome, Rome, Italy
– sequence: 34
  givenname: Giulia
  surname: D'amati
  fullname: D'amati, Giulia
  organization: Department of Radiological, Oncological and Pathological Sciences, "Sapienza" University of Rome, Rome, Italy
– sequence: 35
  givenname: Maria Grazia
  surname: Mancino
  fullname: Mancino, Maria Grazia
  organization: UOC Gastroenterologia ed Endoscopia Digestiva AORN Sant'Anna e San Sebastiano, Caserta, Italy
Copyright 2020 Editrice Gastroenterologica Italiana S.r.l.
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Issue 11
Keywords Gene mutations
Staging
Intrahepatic cholangiocarcinoma
Perihilar cholangiocarcinoma
Histology
Distal cholangiocarcinoma
Risk factors
Language English
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Snippet Cholangiocarcinoma (CCA) is the second most common primary liver cancer, characterized by a poor prognosis and resistance to chemotherapeutics. The progressive...
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SubjectTerms Distal cholangiocarcinoma
Gene mutations
Histology
Intrahepatic cholangiocarcinoma
Perihilar cholangiocarcinoma
Risk factors
Staging
Title Italian Clinical Practice Guidelines on Cholangiocarcinoma – Part I: Classification, diagnosis and staging
URI https://www.clinicalkey.com/#!/content/1-s2.0-S1590865820303339
https://dx.doi.org/10.1016/j.dld.2020.06.045
https://www.ncbi.nlm.nih.gov/pubmed/32893173
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