Single-dose pharmacokinetics, safety, and tolerability of the dual endothelin receptor antagonist aprocitentan in subjects with moderate hepatic impairment - Fontes, Magda S. C.; Dingemanse, Jasper; Halabi, Atef; Tomaszewska-Kiecana, Monika; Sidharta, Patricia N. (Scientific reports, 2022)
Keywords: 692/308; 692/308/153; 692/308/2779/109/1940; Area Under Curve; Endothelin Receptor Antagonists - adverse effects; Humanities and Social Sciences; Humans; Liver Diseases - drug therapy; Liver Diseases - metabolism; multidisciplinary; NCT; NCT04252495; Pyrimidines; Science; Science (multidisciplinary); Sulfonamides