Metabolite profiling of human blood by surface-enhanced Raman spectroscopy for surgery assessment and tumor screening in breast cancer

• Published in: Analytical and bioanalytical chemistry Vol. 412; no. 7; pp. 1611 - 1618
• Main Authors: Lin, Duo, Wang, Yunyi, Wang, Tingyin, Zhu, Youzhi, Lin, Xueliang, Lin, Yao, Feng, Shangyuan
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.03.2020; Springer; Springer Nature B.V
• Subjects: Algorithms; Analysis; Analytical Chemistry; Biochemistry; Blood; blood sampling; Breast cancer; breast neoplasms; Breast Neoplasms - blood; Breast Neoplasms - diagnosis; Breast Neoplasms - surgery; Cancer; Characterization and Evaluation of Materials; Chemistry; Chemistry and Materials Science; death; Diagnosis; Diagnostic systems; Early Detection of Cancer; Female; Food Science; Free surfaces; hematologic tests; Humans; Laboratory Medicine; Mammography; Mass Screening; Medical examination; Metabolites; Metal Nanoparticles - chemistry; Methods; Middle Aged; Monitoring/Environmental Analysis; Nanoparticles; nanosilver; patients; Peripheral blood; Principal Component Analysis; Raman spectroscopy; Research Paper; risk; screening; Sensitivity and Specificity; Silver; Silver - chemistry; Spectroscopy; Spectrum analysis; Spectrum Analysis, Raman - methods; Surgery; Tumors; volunteers; China; Surgery assessment; Blood analysis; Screening; Breast cancer; Silver nanoparticles; Surface-enhanced Raman spectroscopy

Mammography, a standard screening method for breast cancer, is effective for reducing the rate of death; however, it suffers from frequent false positive alarm and radiation risk. Besides, surgery treatment has a vital impact on the clinical outcomes of breast cancer, offering enormous benefits for...