Cold hibernated elastic memory foams for endovascular interventions

• Published in: Biomaterials Vol. 24; no. 3; pp. 491 - 497
• Main Authors: Metcalfe, Annick, Desfaits, Anne-Cécile, Salazkin, Igor, Yahia, L’Hocine, Sokolowski, Witold M, Raymond, Jean
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier Ltd 01.02.2003
• Subjects: Aneurysm; Aneurysm - therapy; Angiography; Animals; Biocompatible Materials; Carotid Artery Diseases - pathology; Carotid Artery Diseases - physiopathology; Cold hibernated elastic memory (CHEM); Dogs; Embolization; Endothelium, Vascular - metabolism; Endovascular; Muscle, Smooth, Vascular - pathology; Mutagenicity Tests; Mutagens; Polyurethane; Polyurethanes - administration & dosage; Polyurethanes - chemistry; Polyurethanes - pharmacology; Shape memory polymer (SMP); Temperature; Time Factors; Embolization; Shape memory polymer (SMP); Cold hibernated elastic memory (CHEM); Polyurethane; Endovascular; Aneurysm

Cold hibernated elastic memory (CHEM) polyurethane-based foam is a new shape memory polymeric self-deployable structure. Standard cytotoxicity and mutagenicity tests were conducted on CHEM in vitro, to ensure biocompatibility before studying potential medical applications. In vivo, lateral wall aneu...