Flavonoid profiling of a traditional Chinese medicine formula of Huangqin Tang using high performance liquid chromatography

• Published in: Acta pharmaceutica Sinica. B Vol. 6; no. 2; pp. 148 - 157
• Main Authors: Li, Tao, Zhuang, Shuaixing, Wang, Yiwei, Wang, Yanli, Wang, Weihao, Zhang, Huihui, Chen, Li, Wang, Dunfang, Zhou, Zhongming, Yang, Weipeng
• Format: Journal Article
• Language: English
• Published: Netherlands Elsevier 01.03.2016
• Subjects: analysis;Multiple-component; analysis;Paw; Anti-inflammatory; Antipyretic; Carrageenin; edema;Carrageenin;Antipyretic;Anti-inflammatory; fingerprinting; Flavonoids; HPLC fingerprinting analysis; Multiple-component quantitative analysis; Original; Paw edema; quantitative; Radix; Radix Scutellariae; Scutellariae;Flavonoids;HPLC; Carrageenin; LC–MSn, liquid chromatography–tandem mass spectrometer; HPLC fingerprinting analysis; Multiple-component quantitative analysis; S/N, signal-to-noise ratio; CFDA, China Food and Drug Administration; RSD, relative standard deviation; PCA, principal component analysis; HPLC, high performance liquid chromatography; TCM, traditional Chinese medicine; HQT, Huangqin Tang; Flavonoids; Paw edema; LLOD, linearity, lower limit of detection; Radix Scutellariae; Antipyretic; ICH, International Conference on Harmonization; LLOQ, lower limit of quantification; Anti-inflammatory

The quality control processes for herbal medicines have been problematic. Flavonoids are the major active components of Huangqin Tang(HQT, a traditional Chinese medicine formula). In this study, we used a combinative method approach consisting of chromatographic fingerprinting(high performance liqui...