Interleukin-6, C-reactive protein and interleukin-10 after antidepressant treatment in people with depression: a meta-analysis

Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inf...

Full description

Saved in:
Bibliographic Details
Published inPsychological medicine Vol. 42; no. 10; pp. 2015 - 2026
Main Authors Hiles, S. A., Baker, A. L., de Malmanche, T., Attia, J.
Format Journal Article
LanguageEnglish
Published Cambridge, UK Cambridge University Press 01.10.2012
Subjects
Adult and adolescent clinical studies
Age
Antidepressant drugs
Antidepressants
Antidepressive Agents - blood
Antidepressive Agents - therapeutic use
Anxiety
Biological and medical sciences
C-Reactive Protein
Clinical outcomes
Cross-Sectional Studies
Cytokines
Depression
Depressive Disorder - blood
Depressive Disorder - complications
Heterogeneity
Humans
Inflammation - blood
Inflammation - complications
Interleukin-10 - blood
Interleukin-6 - blood
Medical sciences
Mental depression
Meta-analysis
Mood disorders
Neuropharmacology
Pharmacology. Drug treatments
Proteins
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
Systematic review
Weight gain
meta-analysis
C-reactive protein
depression
interleukin
systematic review
inflammation
Mood disorder
Psychotropic
Cytokine
Depression
Inflammation
Review
Metaanalysis
Interleukin 6
Treatment
Interleukin 10
Antidepressant agent
C reactive protein
Online AccessGet full text

Cover

Abstract Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression. A computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change. Pooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities. The findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment.
AbstractList Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression. A computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change. Pooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities. The findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment.
Background: Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression. Method: A computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change. Results: Pooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities. Conclusions: The findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment. [PUBLICATION ABSTRACT]
Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression. A computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change. Pooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities. The findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment. Adapted from the source document.
Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression. A computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change. Pooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities. The findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment.
Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression.BACKGROUNDCross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of antidepressant treatment. Our aim was to explore via meta-analysis whether antidepressant treatment is associated with a reduction in three inflammatory markers associated with depression.A computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change.METHODA computerized search of EMBASE, Medline, PsycINFO and Cochrane Library databases was completed using subject headings for depression and either interleukin-6, C-reactive protein or interleukin-10, selecting studies which reported circulating levels of inflammatory markers before and after antidepressant treatment for people with depression. Outcome and moderator variables were coded for analysis, including inflammatory marker change, depression severity change, age, gender ratio, assay brand, treatment response and weight change.Pooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities.RESULTSPooled effect sizes showed a significant decrease in interleukin-6 (n=14, d=-0.42, p=0.02), marginally significant decrease in C-reactive protein (n=8, d=-0.57, p=0.05) and a non-significant decrease in interleukin-10 (n=3, d=-0.45, p=0.14) after treatment. High levels of heterogeneity were observed, which may be associated with clinical variations between the studies such as weight gain, anxiety, incomplete remission and other individual differences and co-morbidities.The findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment.CONCLUSIONSThe findings of this meta-analysis indicate that there may be a normalization of overactive inflammatory processes following antidepressant treatment.
Author Attia, J.
Baker, A. L.
Hiles, S. A.
de Malmanche, T.
Author_xml – sequence: 1
  givenname: S. A.
  surname: Hiles
  fullname: Hiles, S. A.
  email: sarah.hiles@uon.edu.au
  organization: Centre for Brain and Mental Health Research, Faculty of Health, University of Newcastle, New South Wales, Australia
– sequence: 2
  givenname: A. L.
  surname: Baker
  fullname: Baker, A. L.
  organization: Centre for Brain and Mental Health Research, Faculty of Health, University of Newcastle, New South Wales, Australia
– sequence: 3
  givenname: T.
  surname: de Malmanche
  fullname: de Malmanche, T.
  organization: Immunology, Hunter Area Pathology Service, John Hunter Hospital, New South Wales, Australia
– sequence: 4
  givenname: J.
  surname: Attia
  fullname: Attia, J.
  organization: Centre for Clinical Epidemiology and Biostatistics, Faculty of Health, University of Newcastle, New South Wales, Australia
BackLink http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=26309158$$DView record in Pascal Francis
https://www.ncbi.nlm.nih.gov/pubmed/22336436$$D View this record in MEDLINE/PubMed
BookMark eNqNkstu1TAQQC1URG8LH8AGRUJILAh4bMeJu0NXPCpVYgGso0kyAZfECbYD6qbfXkcNUBXxWHmsOWekeRyxAzc5Yuwh8OfAoXzxnnMphYESBOccRHWH7UBpk1emrA7Ybk3na_6QHYVwnhAJStxjh0JIqZXUO3Z56iL5gZYv1uX6WbbPPWEb7TfKZj9Fsi5D12X2BgU8wz59UyLajmZPIaQwi8mMI6UoSTNN80DZdxs_ZxtjJ3eSYTZSxBwdDhfBhvvsbo9DoAfbe8w-vn71Yf82P3v35nT_8ixvCxAxN1i1re5MrwkKUI0wpAC1BlM12JS80QhN35jeiLZqdFGiQmEaritdGN4LecyeXtdNTX1dKMR6tKGlYUBH0xJqUFAWyiiQ_0ZloY3UovwPVIh10lyohD6-hZ5Pi09TWCmty7ICsRZ8tFFLM1JXz96O6C_qH_tKwJMNwNDi0Ht0rQ2_OC25gaJKHFxzrZ9C8NT_RIDX6-3Uv91OcspbTmsjxrS26NEOfzXlZuLYeNt9ohvd_dG6AoaD1EM
CODEN PSMDCO
CitedBy_id crossref_primary_10_1124_pharmrev_122_000618
crossref_primary_10_1007_s12035_018_1016_x
crossref_primary_10_1016_j_bbi_2021_12_025
crossref_primary_10_1016_j_bbih_2021_100353
crossref_primary_10_1371_journal_pone_0111110
crossref_primary_10_1016_j_bbr_2017_05_064
crossref_primary_10_1089_cap_2019_0015
crossref_primary_10_1016_j_tips_2014_04_003
crossref_primary_10_1016_j_bbi_2022_07_006
crossref_primary_10_1038_s41380_020_00867_4
crossref_primary_10_1111_1756_185X_13104
crossref_primary_10_3928_00485713_20250114_03
crossref_primary_10_1097_JCP_0000000000001721
crossref_primary_10_1080_1354750X_2024_2308834
crossref_primary_10_1016_j_jpsychires_2019_03_013
crossref_primary_10_1016_j_bbi_2021_10_018
crossref_primary_10_1016_j_phrs_2023_106833
crossref_primary_10_1080_15622975_2016_1259498
crossref_primary_10_1080_14789450_2017_1336435
crossref_primary_10_1017_S0033291718000090
crossref_primary_10_3390_diseases8020023
crossref_primary_10_1007_s00213_016_4413_8
crossref_primary_10_1111_eci_13268
crossref_primary_10_1089_jwh_2017_6878
crossref_primary_10_1016_j_pnpbp_2017_04_021
crossref_primary_10_1007_s00213_015_3976_0
crossref_primary_10_1017_gmb_2021_3
crossref_primary_10_3390_jcm11144038
crossref_primary_10_1016_j_pnpbp_2017_04_026
crossref_primary_10_1136_bmjopen_2022_067321
crossref_primary_10_1038_s41409_019_0623_0
crossref_primary_10_1016_j_brat_2013_07_005
crossref_primary_10_14412_1995_4484_2019_318_327
crossref_primary_10_1159_000528605
crossref_primary_10_1016_j_bbi_2015_06_001
crossref_primary_10_17116_jnevro202112105284
crossref_primary_10_3390_jcm9123793
crossref_primary_10_1007_s00127_014_0887_z
crossref_primary_10_1002_brb3_885
crossref_primary_10_1007_s00406_021_01245_z
crossref_primary_10_1016_j_bbi_2019_02_021
crossref_primary_10_1016_j_phrs_2023_106893
crossref_primary_10_1111_pcn_12299
crossref_primary_10_1016_j_bbi_2014_03_020
crossref_primary_10_1016_j_exger_2016_10_001
crossref_primary_10_1016_j_jad_2024_06_102
crossref_primary_10_1038_s41380_018_0017_5
crossref_primary_10_1517_14728222_2014_888417
crossref_primary_10_1007_s00424_018_2228_7
crossref_primary_10_1016_j_psyneuen_2018_02_032
crossref_primary_10_1016_j_bbi_2023_09_026
crossref_primary_10_1007_s11920_021_01227_x
crossref_primary_10_1177_0269881114529377
crossref_primary_10_5127_pr_034413
crossref_primary_10_1016_j_bbr_2017_07_041
crossref_primary_10_1016_j_jpsychores_2021_110604
crossref_primary_10_1016_j_ajp_2023_103852
crossref_primary_10_1016_j_euroneuro_2020_07_007
crossref_primary_10_2147_NDT_S442654
crossref_primary_10_1002_wps_20117
crossref_primary_10_3390_dj8010020
crossref_primary_10_3390_brainsci14090850
crossref_primary_10_1016_j_jad_2023_07_016
crossref_primary_10_1016_j_bbi_2012_06_001
crossref_primary_10_1007_s00406_017_0847_1
crossref_primary_10_1080_08039488_2016_1242650
crossref_primary_10_1186_s12888_025_06650_5
crossref_primary_10_1007_s00213_015_4044_5
crossref_primary_10_1016_j_jad_2019_05_002
crossref_primary_10_1016_j_jadr_2022_100427
crossref_primary_10_1016_j_pnpbp_2013_09_017
crossref_primary_10_1021_acs_analchem_4c05967
crossref_primary_10_1016_j_jpsychores_2020_109975
crossref_primary_10_1016_j_pnpbp_2017_09_015
crossref_primary_10_1007_s12160_013_9567_6
crossref_primary_10_1177_1358863X18787640
crossref_primary_10_1186_1741_7015_11_129
crossref_primary_10_1016_j_jad_2017_02_008
crossref_primary_10_17816_MAJ63228
crossref_primary_10_1016_j_jpsychires_2017_10_002
crossref_primary_10_1016_j_lpm_2019_02_002
crossref_primary_10_1111_1754_9485_12583
crossref_primary_10_1186_s12974_025_03403_9
crossref_primary_10_3109_01612840_2013_875086
crossref_primary_10_1097_PSY_0000000000000289
crossref_primary_10_3389_fendo_2021_667773
crossref_primary_10_3390_ijms24043125
crossref_primary_10_1016_j_bbi_2018_05_012
crossref_primary_10_1007_s10865_015_9637_2
crossref_primary_10_3389_fpsyt_2022_1052710
crossref_primary_10_1007_s40266_021_00858_2
crossref_primary_10_1016_j_npbr_2018_10_001
crossref_primary_10_1002_JLB_MR0119_023R
crossref_primary_10_1016_j_psyneuen_2014_09_031
crossref_primary_10_3389_fphar_2022_848939
crossref_primary_10_3390_cells12232749
crossref_primary_10_1016_j_jff_2020_103905
crossref_primary_10_3390_jcm10184142
crossref_primary_10_1089_cap_2015_0147
crossref_primary_10_1016_j_injr_2013_09_005
crossref_primary_10_1080_08039488_2023_2274341
crossref_primary_10_3389_fphar_2021_615695
crossref_primary_10_1002_npr2_12327
crossref_primary_10_1007_s11920_014_0492_6
crossref_primary_10_1016_j_psychres_2017_08_076
crossref_primary_10_1016_j_bbi_2018_11_015
crossref_primary_10_1016_j_euroneuro_2015_06_007
crossref_primary_10_1016_j_jad_2016_06_035
crossref_primary_10_1016_j_jad_2017_11_061
crossref_primary_10_1016_j_bbi_2015_03_016
crossref_primary_10_1016_j_pharmthera_2015_01_001
crossref_primary_10_1017_S0033291716002828
crossref_primary_10_2337_dc16_0710
crossref_primary_10_1176_appi_focus_16206
crossref_primary_10_1016_j_jneuroim_2015_03_012
crossref_primary_10_1016_j_psyneuen_2021_105130
crossref_primary_10_1021_acs_jafc_7b04835
crossref_primary_10_1038_s41398_019_0521_7
crossref_primary_10_1039_D2FO01478E
crossref_primary_10_1016_j_ajp_2017_02_016
crossref_primary_10_3390_jcm9123918
crossref_primary_10_1016_j_psychres_2022_114725
crossref_primary_10_1017_S0033291715000070
crossref_primary_10_1038_s41398_017_0009_2
crossref_primary_10_1016_j_fct_2019_03_004
crossref_primary_10_33808_clinexphealthsci_824534
crossref_primary_10_3390_ijms19010233
crossref_primary_10_1080_15622975_2021_1961502
crossref_primary_10_1097_PSY_0000000000000384
crossref_primary_10_1017_S1092852919001469
crossref_primary_10_1159_000533470
crossref_primary_10_1002_da_22512
crossref_primary_10_1016_j_bbi_2016_12_025
crossref_primary_10_1089_jir_2018_0134
crossref_primary_10_1016_j_bbi_2017_09_005
crossref_primary_10_3389_fpsyt_2020_571636
crossref_primary_10_1016_j_jpsychires_2017_05_004
crossref_primary_10_1177_0269881119874461
crossref_primary_10_1007_s10571_017_0564_3
crossref_primary_10_1016_j_psyneuen_2024_107145
crossref_primary_10_1080_15622975_2016_1208843
crossref_primary_10_1016_j_jad_2014_03_023
crossref_primary_10_1016_j_mcn_2020_103567
crossref_primary_10_1016_j_psc_2023_02_010
crossref_primary_10_1016_j_pnpbp_2019_109657
crossref_primary_10_1017_S1092852921000729
crossref_primary_10_5812_jrps_148619
crossref_primary_10_1038_npp_2014_9
crossref_primary_10_1016_j_bbi_2018_09_024
crossref_primary_10_3389_fpsyt_2023_1325220
crossref_primary_10_1016_j_sleep_2013_04_017
crossref_primary_10_1186_s12993_016_0116_x
crossref_primary_10_1055_a_1717_2381
crossref_primary_10_1016_j_bbi_2019_12_017
crossref_primary_10_1186_s12974_015_0454_x
crossref_primary_10_1016_j_neuron_2020_06_002
crossref_primary_10_1186_1465_9921_14_53
crossref_primary_10_1007_s00281_019_00730_x
crossref_primary_10_7759_cureus_62991
Cites_doi 10.1097/01.jcp.0000168879.03169.ce
10.1038/clpt.2009.121
10.1136/bmj.327.7414.557
10.1016/j.biopsych.2009.09.033
10.1006/cyto.1997.0238
10.1037/0033-2909.86.3.638
10.1017/S1461145702003164
10.1016/j.bbi.2007.01.010
10.1016/j.pnpbp.2009.03.020
10.1016/0165-0327(95)00028-L
10.1016/j.bbi.2010.03.003
10.4088/JCP.v67n1114
10.1155/2010/573594
10.1002/9780470743386
10.1016/j.genhosppsych.2009.10.009
10.1016/j.euroneuro.2010.02.006
10.1159/000054867
10.1016/j.jad.2005.03.005
10.1016/S0924-977X(01)00081-5
10.1159/000119332
10.1097/PSY.0b013e3181907c1b
10.1080/10253890701850759
10.1055/s-0029-1202263
10.1016/j.biopsych.2005.05.001
10.1056/NEJM199902113400607
10.1016/j.euroneuro.2008.08.001
10.1007/s004060170058
10.1291/hypres.30.285
10.1002/hup.1103
10.1111/j.1749-6632.1995.tb32372.x
10.1111/j.1440-1681.2008.05077.x
10.1016/j.psychres.2009.04.013
10.1006/brbi.2000.0597
10.1007/s00213-003-1566-z
10.1016/j.diabres.2004.11.007
10.1016/j.biopsych.2009.01.030
10.4088/JCP.09r05346blu
10.1136/bmj.315.7109.629
10.1002/hup.191
10.1016/j.biopsych.2008.11.029
10.1016/S0893-133X(99)00134-7
10.1002/hup.717
10.1007/s11011-008-9118-1
10.1146/annurev.immunol.19.1.683
10.2147/NDT.S16382
10.1136/bmj.309.6957.780
10.1192/bjp.bp.105.011015
ContentType Journal Article
Copyright Copyright © Cambridge University Press 2012
2015 INIST-CNRS
Copyright_xml – notice: Copyright © Cambridge University Press 2012
– notice: 2015 INIST-CNRS
DBID AAYXX
CITATION
IQODW
CGR
CUY
CVF
ECM
EIF
NPM
0-V
3V.
7QJ
7QP
7QR
7RV
7TK
7X7
7XB
88E
88G
8FD
8FI
8FJ
8FK
8G5
ABUWG
AFKRA
ALSLI
AZQEC
BENPR
CCPQU
DWQXO
FR3
FYUFA
GHDGH
GNUQQ
GUQSH
HEHIP
K9.
KB0
M0S
M1P
M2M
M2O
M2S
MBDVC
NAPCQ
P64
PHGZM
PHGZT
PJZUB
PKEHL
POGQB
PPXIY
PQEST
PQQKQ
PQUKI
PRINS
PRQQA
PSYQQ
Q9U
7X8
DOI 10.1017/S0033291712000128
DatabaseName CrossRef
Pascal-Francis
Medline
MEDLINE
MEDLINE (Ovid)
MEDLINE
MEDLINE
PubMed
ProQuest Social Sciences Premium Collection
ProQuest Central (Corporate)
Applied Social Sciences Index & Abstracts (ASSIA)
Calcium & Calcified Tissue Abstracts
Chemoreception Abstracts
Nursing & Allied Health Database
Neurosciences Abstracts
Health & Medical Collection
ProQuest Central (purchase pre-March 2016)
Medical Database (Alumni Edition)
Psychology Database (Alumni)
Technology Research Database
Hospital Premium Collection
Hospital Premium Collection (Alumni Edition)
ProQuest Central (Alumni) (purchase pre-March 2016)
ProQuest Research Library
ProQuest Central (Alumni)
ProQuest Central UK/Ireland
Social Science Premium Collection
ProQuest Central Essentials
ProQuest Central
ProQuest One
ProQuest Central Korea
Engineering Research Database
Health Research Premium Collection
Health Research Premium Collection (Alumni)
ProQuest Central Student
ProQuest Research Library
Sociology Collection
ProQuest Health & Medical Complete (Alumni)
Nursing & Allied Health Database (Alumni Edition)
Health & Medical Collection (Alumni)
Medical Database
Psychology Database
Research Library
Sociology Database
Research Library (Corporate)
Nursing & Allied Health Premium
Biotechnology and BioEngineering Abstracts
ProQuest Central Premium
ProQuest One Academic (New)
ProQuest Health & Medical Research Collection
ProQuest One Academic Middle East (New)
ProQuest Sociology & Social Sciences Collection
ProQuest One Health & Nursing
ProQuest One Academic Eastern Edition (DO NOT USE)
ProQuest One Academic
ProQuest One Academic UKI Edition
ProQuest Central China
ProQuest One Social Sciences
ProQuest One Psychology
ProQuest Central Basic
MEDLINE - Academic
DatabaseTitle CrossRef
MEDLINE
Medline Complete
MEDLINE with Full Text
PubMed
MEDLINE (Ovid)
ProQuest One Psychology
Research Library Prep
ProQuest Central Student
ProQuest Central Essentials
Sociology & Social Sciences Collection
ProQuest Central China
Health Research Premium Collection
Health & Medical Research Collection
Chemoreception Abstracts
ProQuest Central (New)
ProQuest Sociology
ProQuest Medical Library (Alumni)
Social Science Premium Collection
ProQuest One Academic Eastern Edition
ProQuest Hospital Collection
Sociology Collection
Health Research Premium Collection (Alumni)
Neurosciences Abstracts
ProQuest Hospital Collection (Alumni)
Biotechnology and BioEngineering Abstracts
Nursing & Allied Health Premium
ProQuest Health & Medical Complete
ProQuest Social Sciences Premium Collection
ProQuest One Academic UKI Edition
ProQuest Nursing & Allied Health Source (Alumni)
Engineering Research Database
ProQuest One Academic
Calcium & Calcified Tissue Abstracts
ProQuest One Academic (New)
Technology Research Database
ProQuest One Academic Middle East (New)
ProQuest Health & Medical Complete (Alumni)
ProQuest Central (Alumni Edition)
ProQuest One Community College
ProQuest One Health & Nursing
Research Library (Alumni Edition)
Applied Social Sciences Index and Abstracts (ASSIA)
ProQuest Central
Health and Medicine Complete (Alumni Edition)
ProQuest Central Korea
ProQuest Research Library
ProQuest Sociology Collection
ProQuest One Social Sciences
ProQuest Central Basic
ProQuest Nursing & Allied Health Source
ProQuest Psychology Journals (Alumni)
ProQuest Medical Library
ProQuest Psychology Journals
ProQuest Central (Alumni)
MEDLINE - Academic
DatabaseTitleList MEDLINE
ProQuest One Psychology
Applied Social Sciences Index and Abstracts (ASSIA)
Neurosciences Abstracts
MEDLINE - Academic
Database_xml – sequence: 1
  dbid: NPM
  name: PubMed
  url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed
  sourceTypes: Index Database
– sequence: 2
  dbid: EIF
  name: MEDLINE
  url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search
  sourceTypes: Index Database
– sequence: 3
  dbid: BENPR
  name: ProQuest Central
  url: https://www.proquest.com/central
  sourceTypes: Aggregation Database
DeliveryMethod fulltext_linktorsrc
Discipline Medicine
DocumentTitleAlternate Inflammatory markers and antidepressants
S. A. Hiles et al.
EISSN 1469-8978
EndPage 2026
ExternalDocumentID 2858701181
22336436
26309158
10_1017_S0033291712000128
Genre Research Support, Non-U.S. Gov't
Meta-Analysis
Journal Article
GroupedDBID ---
-1D
-1F
-2P
-2V
-E.
-~6
-~N
.FH
.GJ
.XZ
0-V
08P
09C
09E
0E1
0R~
123
29P
3V.
4.4
41~
53G
5RE
5VS
6~7
74X
74Y
7RV
7X7
7~V
88E
8FI
8FJ
8G5
8R4
8R5
9M5
AAAZR
AABES
AABWE
AACJH
AAGFV
AAKTX
AAMNQ
AARAB
AASVR
AATMM
AAUIS
AAUKB
AAWTL
AAYEP
ABBXD
ABBZL
ABGDZ
ABITZ
ABIVO
ABJNI
ABKKG
ABLJU
ABQTM
ABQWD
ABROB
ABTCQ
ABUWG
ABVFV
ABVKB
ABVZP
ABWCF
ABXAU
ABZCX
ABZUI
ACBMC
ACDLN
ACETC
ACGFO
ACGFS
ACHQT
ACIMK
ACIWK
ACPRK
ACRPL
ACUIJ
ACYZP
ACZBM
ACZUX
ADAZD
ADBBV
ADDNB
ADFEC
ADFRT
ADKIL
ADNMO
ADOVH
ADOVT
ADVJH
AEBAK
AEBPU
AEHGV
AEMFK
AEMTW
AENCP
AENEX
AENGE
AEPLO
AEYHU
AEYYC
AFFNX
AFFUJ
AFKQG
AFKRA
AFLOS
AFLVW
AFUTZ
AFZFC
AGABE
AGJUD
AGLWM
AHIPN
AHLTW
AHMBA
AHQXX
AHRGI
AIGNW
AIHIV
AIOIP
AISIE
AJ7
AJCYY
AJPFC
AJQAS
AKZCZ
ALIPV
ALMA_UNASSIGNED_HOLDINGS
ALSLI
ALVPG
ANPSP
AQJOH
ARABE
ARALO
ARZZG
ASOEW
ATUCA
AUXHV
AYIQA
AZGZS
AZQEC
BBLKV
BCGOX
BENPR
BESQT
BGHMG
BJBOZ
BKEYQ
BLZWO
BMAJL
BPHCQ
BQFHP
BRIRG
BVXVI
C0O
C45
CAG
CBIIA
CCPQU
CCQAD
CCUQV
CDIZJ
CFAFE
CFBFF
CGQII
CHEAL
CJCSC
COF
CS3
DC4
DOHLZ
DU5
DWQXO
EBS
EGQIC
EJD
EX3
F5P
FA8
FYUFA
GNUQQ
GUQSH
HEHIP
HG-
HMCUK
HST
HZ~
H~9
I.6
I.7
I.9
IH6
IOEEP
IOO
IS6
I~P
J36
J38
J3A
J5H
JHPGK
JQKCU
JVRFK
KAFGG
KCGVB
KFECR
L7B
L98
LHUNA
LW7
M-V
M1P
M2M
M2O
M2S
M7~
M8.
N4W
NAPCQ
NEJ
NIKVX
NMFBF
NZEOI
O9-
OMB
OMC
OMH
OVD
OYBOY
P2P
PQQKQ
PROAC
PSQYO
PSYQQ
Q2X
RCA
RIG
ROL
RR0
S6-
S6U
SAAAG
SY4
T9M
TEORI
UAP
UCJ
UKHRP
UT1
UU6
VVN
WFFJZ
WH7
WOW
WQ3
WXU
WYP
YOC
YZZ
ZCA
ZDLDU
ZGI
ZJOSE
ZMEZD
ZXP
ZYDXJ
~V1
AAKNA
AAYXX
ABHFL
ABXHF
ACEJA
ACOZI
ADPDF
AGQPQ
AKMAY
ANOYL
CITATION
IPYYG
PHGZM
PHGZT
AGKLZ
IQODW
AAFWJ
CGR
CUY
CVF
ECM
EIF
NPM
PJZUB
POGQB
PPXIY
PRQQA
7QJ
7QP
7QR
7TK
7XB
8FD
8FK
FR3
K9.
MBDVC
P64
PKEHL
PQEST
PQUKI
PRINS
Q9U
7X8
PUEGO
ID FETCH-LOGICAL-c512t-9a8cc6d9f6e1514b29e41a66198bab70b6a1bfb9f92c8b657a4a29b0686590f23
IEDL.DBID 7X7
ISSN 0033-2917
1469-8978
IngestDate Fri Jul 11 06:06:49 EDT 2025
Mon Jul 21 09:24:17 EDT 2025
Sun Aug 24 03:27:37 EDT 2025
Fri Jul 25 06:04:24 EDT 2025
Mon Jul 21 06:02:03 EDT 2025
Wed Apr 02 07:21:10 EDT 2025
Thu Apr 24 23:03:27 EDT 2025
Tue Jul 01 04:15:44 EDT 2025
Tue Jan 21 06:24:49 EST 2025
IsDoiOpenAccess false
IsOpenAccess true
IsPeerReviewed true
IsScholarly true
Issue 10
Keywords meta-analysis
C-reactive protein
depression
interleukin
systematic review
inflammation
Mood disorder
Psychotropic
Cytokine
Depression
Inflammation
Review
Metaanalysis
Interleukin 6
Treatment
Interleukin 10
Antidepressant agent
C reactive protein
Language English
License https://www.cambridge.org/core/terms
CC BY 4.0
LinkModel DirectLink
MergedId FETCHMERGED-LOGICAL-c512t-9a8cc6d9f6e1514b29e41a66198bab70b6a1bfb9f92c8b657a4a29b0686590f23
Notes ObjectType-Article-2
SourceType-Scholarly Journals-1
ObjectType-Feature-1
content type line 14
ObjectType-Article-1
ObjectType-Feature-2
content type line 23
OpenAccessLink https://www.cambridge.org/core/services/aop-cambridge-core/content/view/FA113E446CFF114874D9F4C96798FF70/S0033291712000128a.pdf/div-class-title-interleukin-6-c-reactive-protein-and-interleukin-10-after-antidepressant-treatment-in-people-with-depression-a-meta-analysis-div.pdf
PMID 22336436
PQID 1266778123
PQPubID 35753
PageCount 12
ParticipantIDs proquest_miscellaneous_1417549413
proquest_miscellaneous_1356936273
proquest_miscellaneous_1222233024
proquest_journals_1266778123
pubmed_primary_22336436
pascalfrancis_primary_26309158
crossref_primary_10_1017_S0033291712000128
crossref_citationtrail_10_1017_S0033291712000128
cambridge_journals_10_1017_S0033291712000128
ProviderPackageCode CITATION
AAYXX
PublicationCentury 2000
PublicationDate 2012-10-01
PublicationDateYYYYMMDD 2012-10-01
PublicationDate_xml – month: 10
  year: 2012
  text: 2012-10-01
  day: 01
PublicationDecade 2010
PublicationPlace Cambridge, UK
PublicationPlace_xml – name: Cambridge, UK
– name: Cambridge
– name: England
PublicationTitle Psychological medicine
PublicationTitleAlternate Psychol Med
PublicationYear 2012
Publisher Cambridge University Press
Publisher_xml – name: Cambridge University Press
References S0033291712000128_ref050
S0033291712000128_ref018
S0033291712000128_ref017
S0033291712000128_ref016
S0033291712000128_ref015
S0033291712000128_ref019
S0033291712000128_ref010
S0033291712000128_ref053
S0033291712000128_ref052
Pudar Hozo (S0033291712000128_ref041) 2005; 5
S0033291712000128_ref014
S0033291712000128_ref013
S0033291712000128_ref012
S0033291712000128_ref011
S0033291712000128_ref007
S0033291712000128_ref006
S0033291712000128_ref049
S0033291712000128_ref004
S0033291712000128_ref048
S0033291712000128_ref009
S0033291712000128_ref008
S0033291712000128_ref043
S0033291712000128_ref042
S0033291712000128_ref040
S0033291712000128_ref047
S0033291712000128_ref003
S0033291712000128_ref046
S0033291712000128_ref002
S0033291712000128_ref045
S0033291712000128_ref001
S0033291712000128_ref044
Yao (S0033291712000128_ref051) 2004; 8
S0033291712000128_ref038
S0033291712000128_ref037
S0033291712000128_ref032
S0033291712000128_ref031
S0033291712000128_ref030
S0033291712000128_ref036
Kubera (S0033291712000128_ref024) 2000; 52
S0033291712000128_ref035
S0033291712000128_ref034
S0033291712000128_ref033
S0033291712000128_ref029
S0033291712000128_ref028
S0033291712000128_ref027
S0033291712000128_ref026
S0033291712000128_ref021
S0033291712000128_ref020
S0033291712000128_ref025
S0033291712000128_ref023
S0033291712000128_ref022
References_xml – ident: S0033291712000128_ref023
  doi: 10.1097/01.jcp.0000168879.03169.ce
– ident: S0033291712000128_ref040
  doi: 10.1038/clpt.2009.121
– ident: S0033291712000128_ref016
  doi: 10.1136/bmj.327.7414.557
– ident: S0033291712000128_ref010
  doi: 10.1016/j.biopsych.2009.09.033
– ident: S0033291712000128_ref030
  doi: 10.1006/cyto.1997.0238
– ident: S0033291712000128_ref042
  doi: 10.1037/0033-2909.86.3.638
– ident: S0033291712000128_ref050
– ident: S0033291712000128_ref022
  doi: 10.1017/S1461145702003164
– ident: S0033291712000128_ref018
  doi: 10.1016/j.bbi.2007.01.010
– ident: S0033291712000128_ref052
  doi: 10.1016/j.pnpbp.2009.03.020
– ident: S0033291712000128_ref031
  doi: 10.1016/0165-0327(95)00028-L
– ident: S0033291712000128_ref037
  doi: 10.1016/j.bbi.2010.03.003
– ident: S0033291712000128_ref026
  doi: 10.4088/JCP.v67n1114
– ident: S0033291712000128_ref008
  doi: 10.1155/2010/573594
– ident: S0033291712000128_ref003
  doi: 10.1002/9780470743386
– ident: S0033291712000128_ref004
  doi: 10.1016/j.genhosppsych.2009.10.009
– volume: 5
  year: 2005
  ident: S0033291712000128_ref041
  article-title: Estimating the mean and variance from the median, range, and the size of a sample
  publication-title: BMC Medical Research Methodology
– ident: S0033291712000128_ref006
  doi: 10.1016/j.euroneuro.2010.02.006
– ident: S0033291712000128_ref021
  doi: 10.1159/000054867
– ident: S0033291712000128_ref044
  doi: 10.1016/j.jad.2005.03.005
– ident: S0033291712000128_ref033
  doi: 10.1016/S0924-977X(01)00081-5
– ident: S0033291712000128_ref047
  doi: 10.1159/000119332
– ident: S0033291712000128_ref017
  doi: 10.1097/PSY.0b013e3181907c1b
– volume: 8
  start-page: 2978
  year: 2004
  ident: S0033291712000128_ref051
  article-title: Variety of cell-mediated immunity and the metabolic products of monoamine neural transmitter in depression patients before and after therapy
  publication-title: Chinese Journal of Clinical Rehabilitation
– ident: S0033291712000128_ref007
  doi: 10.1080/10253890701850759
– ident: S0033291712000128_ref048
  doi: 10.1055/s-0029-1202263
– ident: S0033291712000128_ref012
  doi: 10.1016/j.biopsych.2005.05.001
– ident: S0033291712000128_ref014
  doi: 10.1056/NEJM199902113400607
– ident: S0033291712000128_ref015
  doi: 10.1016/j.euroneuro.2008.08.001
– ident: S0033291712000128_ref043
  doi: 10.1007/s004060170058
– ident: S0033291712000128_ref009
  doi: 10.1291/hypres.30.285
– ident: S0033291712000128_ref019
  doi: 10.1002/hup.1103
– ident: S0033291712000128_ref046
  doi: 10.1111/j.1749-6632.1995.tb32372.x
– ident: S0033291712000128_ref028
  doi: 10.1111/j.1440-1681.2008.05077.x
– ident: S0033291712000128_ref020
  doi: 10.1016/j.psychres.2009.04.013
– ident: S0033291712000128_ref053
  doi: 10.1006/brbi.2000.0597
– ident: S0033291712000128_ref049
  doi: 10.1007/s00213-003-1566-z
– ident: S0033291712000128_ref038
  doi: 10.1016/j.diabres.2004.11.007
– ident: S0033291712000128_ref027
  doi: 10.1016/j.biopsych.2009.01.030
– ident: S0033291712000128_ref045
  doi: 10.4088/JCP.09r05346blu
– ident: S0033291712000128_ref011
  doi: 10.1136/bmj.315.7109.629
– volume: 52
  start-page: 237
  year: 2000
  ident: S0033291712000128_ref024
  article-title: Plasma levels of interleukin-6, interleukin-10, and interleukin-1 receptor antagonist in depression: comparison between the acute state and after remission
  publication-title: Polish Journal of Pharmacology
– ident: S0033291712000128_ref029
  doi: 10.1002/hup.191
– ident: S0033291712000128_ref034
  doi: 10.1016/j.biopsych.2008.11.029
– ident: S0033291712000128_ref025
  doi: 10.1016/S0893-133X(99)00134-7
– ident: S0033291712000128_ref001
  doi: 10.1002/hup.717
– ident: S0033291712000128_ref032
  doi: 10.1007/s11011-008-9118-1
– ident: S0033291712000128_ref035
  doi: 10.1146/annurev.immunol.19.1.683
– ident: S0033291712000128_ref013
  doi: 10.2147/NDT.S16382
– ident: S0033291712000128_ref002
  doi: 10.1136/bmj.309.6957.780
– ident: S0033291712000128_ref036
  doi: 10.1192/bjp.bp.105.011015
SSID ssj0013142
Score 2.4787636
SecondaryResourceType review_article
Snippet Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the context of...
Background: Cross-sectional studies support an association between depression and inflammatory markers. However, little is known of their relationship in the...
SourceID proquest
pubmed
pascalfrancis
crossref
cambridge
SourceType Aggregation Database
Index Database
Enrichment Source
Publisher
StartPage 2015
SubjectTerms Adult and adolescent clinical studies
Age
Antidepressant drugs
Antidepressants
Antidepressive Agents - blood
Antidepressive Agents - therapeutic use
Anxiety
Biological and medical sciences
C-Reactive Protein
Clinical outcomes
Cross-Sectional Studies
Cytokines
Depression
Depressive Disorder - blood
Depressive Disorder - complications
Heterogeneity
Humans
Inflammation - blood
Inflammation - complications
Interleukin-10 - blood
Interleukin-6 - blood
Medical sciences
Mental depression
Meta-analysis
Mood disorders
Neuropharmacology
Pharmacology. Drug treatments
Proteins
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer
Psychoanaleptics: cns stimulant, antidepressant agent, nootropic agent, mood stabilizer..., (alzheimer disease)
Psychology. Psychoanalysis. Psychiatry
Psychopathology. Psychiatry
Psychopharmacology
Systematic review
Weight gain
Title Interleukin-6, C-reactive protein and interleukin-10 after antidepressant treatment in people with depression: a meta-analysis
URI https://www.cambridge.org/core/product/identifier/S0033291712000128/type/journal_article
https://www.ncbi.nlm.nih.gov/pubmed/22336436
https://www.proquest.com/docview/1266778123
https://www.proquest.com/docview/1222233024
https://www.proquest.com/docview/1356936273
https://www.proquest.com/docview/1417549413
Volume 42
hasFullText 1
inHoldings 1
isFullTextHit
isPrint
link http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV3da9swED-2FsagjH222bqgwp5GxWRZlqy9jK20lELLGCvkLUiyDKGtkzbOa__2nmTFTRnzm5FOttBJdz_fne4Avkhei0ppS1llGBWoBKjFfyGKqlFX0iov4w258wt5einOJsUkGdyWKaxyLROjoK7mLtjIv2WoSZRCdZT_WNzSUDUqeFdTCY3nsB1Sl4WQLjVRj16ETHTZwmO9skytvZoxZTQ2hraMR2NMuZlb4YmO2lmYJS5X3dW5-D8QjQrp5DW8SkiS_OxY_wae-eYtvDhPvvJ3cB-Nfdd-dTVrqDwkRxTxYZRuJCZnmDXENBWZbVBljMSa4djRzlKMLD6SPhodqUkXc06CAZf0cbTNd2LIjW8NNSnLyXu4PDn-e3RKU7UF6lDpt1Sb0jlZ6Vp6RAHCcu1FZlB969Iaq5iVJrO11bXmrrSyUEYYrm24YlJoVvP8A2w188bvASlyl0vmOKsRoDjDragkihZb1jlzQrERHPZrPU1nZjnt4s3U9B_WjICt2TF1KXN5KKBxPTTkaz9k0aXtGCIeP-FxP4LLHOFUgQT7a6ZvTLffkCM46LvxcAaPi2n8fBVoAvzKEQcN0OSF1Agj1NB7BKI8oRFwjGC323SPk8QPIKyUH4cn-QleItbjXRziPmy1dyv_GfFUa8fx0Ixh-9fxxe8_DzfgGO8
linkProvider ProQuest
linkToHtml http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3daxQxEB_KFVQQ8dvTWiPoizS4m80mG0FEa8vV9g6RFvq2TbJZOKx7p3eH-OKf5N_oJPvRK-K-9W3ZneyGnWR-v2QmMwAvBCt5IZWhUaEjyhEEqMG1EEVoVIUw0olwQm48EaMT_uk0Pd2AP-1ZGB9W2drEYKiLmfV75K9jRBIpEY6Sd_Pv1FeN8t7VtoRGPSwO3a-fuGRbvD34iPp9ydj-3vHuiDZVBahFcFtSpTNrRaFK4RDtuGHK8VgjTKnMaCMjI3RsSqNKxWxmRCo110wZf5QiVVHpEx2gyd_kCS5lBrD5YW_y-cuF3yLmdX7yUCEtlq0fNSSpxpv-XszC9k-2ns3hEirenOsFKqisK2v8n_oGCNy_Dbca7kre14PtDmy46i5cGzfe-XvwO2wvnrvV12lFxQ7ZpchIgz0lIR3EtCK6Ksh0TSqOSKhSjg-W0yYqFy9JF_-O0qSOcid-y5h0kbvVG6LJN7fUVDd5Ve7DyZVo4gEMqlnlHgFJE4v6sCwqkRJZzQwvBBozk5VJZLmMhrDT_eu8maWLvI5wk_k_qhlC1Kojt02udF-y47yvyauuybxOFNInvH1Jx10LJhIkcCkKbLVKX-tuNwWG8Lx7jObA-3h05WYrL-MJX4LMq0cmSYVC4iL73sORV3KFFGcID-tBd9FJ_AASWfG4v5PP4ProeHyUHx1MDp_ADWSarI6C3ILB8sfKPUU2tzTbzRQicHbVs_Yvbp5Vbg
linkToPdf http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwtV3faxQxEA6lhSKI-LuntUbQF2loNptNNoUi0nq01hYfLNzbmmSzcFj3Tm-P4ot_mH-dk2R3e0Xct74tu5PbcJOZ79vMZAah14JVvJTKEFpqSjiAADHwLUQAGlUpjHQinJA7OxfHF_zjJJusoT_dWRifVtn5xOCoy5n1e-R7CSCJlABH6V7VpkV8Phq_m_8gvoOUj7R27TTiEjl1v67g821xcHIEun7D2PjDl8Nj0nYYIBaAriFK59aKUlXCAfJxw5TjiQbIUrnRRlIjdGIqoyrFbG5EJjXXTBl_rCJTtPJFD8D9b8g0S7yNyYm8jmAkPFYqD73SEtlFVEO5arjp7yUsbATlq3UdbuDj3blegKqq2GPj_yQ4gOH4PrrXslj8Pi67B2jN1Q_R5lkbp3-EfoeNxku3_DatidjFhwS4afCsOBSGmNZY1yWerkglFId-5fCgmbb5uXCJ-0x4kMYx3x37zWPc5_DW-1jj767RRLcVVh6ji1vRwxO0Xs9qt4VwltpUUMtoBeTIamZ4KcCtmbxKqeWSjtBu_18Xrb0uipjrJot_VDNCtFNHYduq6b55x-XQkLf9kHksGTIkvHNDx_0IJlKgchkIbHdKX5lubwwj9Kp_DI7BR3t07WZLL-OpXwocbEAmzYQCCiOHfocDw-QKyM4IPY2L7nqS8AKgtOLZ8CRfok2w1eLTyfnpc3QHKCeL6ZDbaL35uXQvgNY1ZifYD0Zfb9tg_wLV2Vg-
openUrl ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Interleukin-6%2C+C-reactive+protein+and+interleukin-10+after+antidepressant+treatment+in+people+with+depression%3A+a+meta-analysis&rft.jtitle=Psychological+medicine&rft.au=Hiles%2C+S+A&rft.au=Baker%2C+A+L&rft.au=de+Malmanche%2C+T&rft.au=Attia%2C+J&rft.date=2012-10-01&rft.issn=0033-2917&rft.volume=42&rft.issue=10&rft.spage=2015&rft.epage=2026&rft_id=info:doi/10.1017%2FS0033291712000128&rft.externalDBID=NO_FULL_TEXT
thumbnail_l http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0033-2917&client=summon
thumbnail_m http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0033-2917&client=summon
thumbnail_s http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0033-2917&client=summon