Nose-To-Brain Delivery of PLGA-Diazepam Nanoparticles - Sharma, Deepak; Sharma, Rakesh Kumar; Sharma, Navneet; Gabrani, Reema; Sharma, Sanjeev K.; Ali, Javed; Dang, Shweta (AAPS PharmSciTech, 2015)
Keywords: Administration, Intranasal; Animals; Biochemistry; Biomedical and Life Sciences; Biomedicine; Biotechnology; Brain - diagnostic imaging; Brain - metabolism; Calorimetry, Differential Scanning; Cell Survival - drug effects; Cercopithecus aethiops; Chemical Precipitation; Diazepam - administration & dosage; Diazepam - chemistry; Diazepam - metabolism; Diazepam - toxicity; Drug Carriers; Drug Compounding; Lactic Acid - chemistry; Male; Nanoparticles; Nanotechnology - methods; Nasal Absorption; Nasal Mucosa - diagnostic imaging; Nasal Mucosa - metabolism; Particle Size; Pharmacology/Toxicology; Pharmacy; Polyglycolic Acid - chemistry; Radiopharmaceuticals - administration & dosage; Radiopharmaceuticals - chemistry; Radiopharmaceuticals - metabolism; Radiopharmaceuticals - toxicity; Rats, Sprague-Dawley; Research Article; Solubility; Spectroscopy, Fourier Transform Infrared; Surface-Active Agents - chemistry; Tissue Distribution; Vero Cells; process optimization; controlled release; nanoparticles; scintigraphy