Protein kinase D at the Golgi controls NLRP3 inflammasome activation - Zhang, Zhirong; Meszaros, Gergö; He, Wan-ting; Xu, Yanfang; de Fatima Magliarelli, Helena; Mailly, Laurent; Mihlan, Michael; Liu, Yansheng; Puig Gámez, Marta; Goginashvili, Alexander; Pasquier, Adrien; Bielska, Olga; et al. (The Journal of experimental medicine, 2017)
Keywords: Activation; Animals; Assembly; Cytosol; Deactivation; Diglycerides; Diglycerides - metabolism; Endoplasmic reticulum; Endoplasmic Reticulum - physiology; Golgi apparatus; Golgi Apparatus - physiology; Hazards; Humans; Immune response; Inactivation; Inflammasomes; Inflammasomes - physiology; Innate immunity; Kinases; Leukocytes (mononuclear); Leukocytes, Mononuclear - metabolism; Membranes; Mice; Mice, Inbred C57BL; Mice, Knockout; Mitochondria; Mutation; NLR Family, Pyrin Domain-Containing 3 Protein - physiology; Oligomerization; Peripheral blood mononuclear cells; Phosphorylation; Protein kinase; Protein Kinase C - physiology; Proteins; Signaling