Expressions of natural cytotoxicity receptor, NKG2D and NKG2D ligands in endometriosis

• Published in: Journal of reproductive immunology Vol. 136; p. 102615
• Main Author: Xu, Hong
• Format: Journal Article
• Language: English
• Published: Ireland Elsevier B.V 01.11.2019
• Subjects: Adult; CD56 Antigen - immunology; Endometriosis - immunology; Endometriosis - pathology; Female; Gene Expression Regulation - immunology; GPI-Linked Proteins - immunology; Humans; Killer Cells, Natural - immunology; Killer Cells, Natural - pathology; Middle Aged; Natural cytotoxicity receptors; Natural Cytotoxicity Triggering Receptor 1 - immunology; Natural Cytotoxicity Triggering Receptor 3 - immunology; NK Cell Lectin-Like Receptor Subfamily K - immunology; NKG2D; NKG2D ligands; Ovarian endometriosis; Receptors, IgG - immunology; Ovarian endometriosis; NKG2D; NKG2D ligands; Natural cytotoxicity receptors

•The relationship between NCRs, NKG2D and NKG2D ligands and the pathogenesis of endometriosis is investigated.•In PF with endometriosis, expressions of NKp30 and NKG2D on CD56+NK cells were decreased, but expression of NKp46 on CD16+NK cells was increased.•It may indicate that pelvic endometriosis i...