Retinal thickness in patients with mild cognitive impairment and Alzheimer's disease

• Published in: Clinical neurology and neurosurgery Vol. 113; no. 7; pp. 523 - 526
• Main Authors: Kesler, Anat, Vakhapova, Veronika, Korczyn, Amos D, Naftaliev, Elvira, Neudorfer, Meira
• Format: Journal Article
• Language: English
• Published: Amsterdam Elsevier B.V 01.09.2011; Elsevier; Elsevier Limited
• Subjects: Aged; Aged, 80 and over; Alzheimer Disease - pathology; Alzheimer Disease - psychology; Alzheimer's disease; Axons - pathology; Biological and medical sciences; Cognition Disorders - pathology; Cognition Disorders - psychology; Dementia; Diagnostic and Statistical Manual of Mental Disorders; Female; Glaucoma; Humans; Male; Medical sciences; Mild cognitive impairment; Nerve Degeneration - pathology; Nerve Fibers - pathology; Nerve Fibers - ultrastructure; Neurology; Neuropsychological Tests; Neurosurgery; Optic nerve; Optical coherence tomography; Retina - pathology; Retina - ultrastructure; Retinal Ganglion Cells - pathology; Retinal nerve fiber layer thickness; Retinal Neurons - pathology; Retinal Neurons - ultrastructure; Studies; Surgery (general aspects). Transplantations, organ and tissue grafts. Graft diseases; Tomography, Optical Coherence; Optical coherence tomography; Retinal nerve fiber layer thickness; Mild cognitive impairment; Alzheimer's disease; Human; Nervous system diseases; Cognitive disorder; Alzheimer disease; Retina; Cerebral disorder; Surgery; Central nervous system disease; Degenerative disease; mild cognitive impairment; Nerve fiber

Abstract Objectives Mild cognitive impairment (MCI) may represent a transition to early Alzheimer's disease (AD). The retinal nerve fiber layer (RNFL) is composed of axons originating in retinal ganglion cells that eventually form the optic nerves. Previous studies have shown that degenerative...