Topologically convergent and divergent functional connectivity patterns in unmedicated unipolar depression and bipolar disorder

• Published in: Translational psychiatry Vol. 7; no. 7; p. e1165
• Main Authors: Wang, Y, Wang, J, Jia, Y, Zhong, S, Zhong, M, Sun, Y, Niu, M, Zhao, L, Pan, J, Huang, L, Huang, R
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 04.07.2017; Nature Publishing Group
• Subjects: 59/36; 59/57; 692/699/476/1333; 692/699/476/1414; Adolescent; Adult; Behavioral Sciences; Biological Psychology; Bipolar disorder; Bipolar Disorder - physiopathology; Brain - physiopathology; Connectome; Depressive Disorder - physiopathology; Female; Humans; Magnetic Resonance Imaging; Male; Medicine; Medicine & Public Health; Mental depression; Middle Aged; Models, Neurological; Neural Pathways - physiopathology; Neurosciences; Original; original-article; Pharmacotherapy; Psychiatry; Young Adult

Bipolar disorder (BD), particularly BD II, is frequently misdiagnosed as unipolar depression (UD), leading to inappropriate treatment and poor clinical outcomes. Although depressive symptoms may be expressed similarly in UD and BD, the similarities and differences in the architecture of brain functi...