Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium Bacillus licheniformis YB9 with the Capability of Modulating Intestinal Microbial Flora of Mice
Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to d...
Saved in:
| Published in | Toxins Vol. 12; no. 3; p. 184 |
|---|---|
| Main Authors | , , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Switzerland
MDPI AG
15.03.2020
MDPI |
| Subjects | |
| Online Access | Get full text |
Cover
Loading…
| Abstract | Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a
strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium
and the excessive
caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals. |
|---|---|
| AbstractList | Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a
strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium
and the excessive
caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals. Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a Bacillus licheniformis strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 [degrees]C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium Turicibacter and the excessive Lactobacillus caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals. Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a Bacillus licheniformis strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium Turicibacter and the excessive Lactobacillus caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals. Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious threats to human and animal health and leads to tremendous economic losses globally. Much attention has been paid to using microorganisms to detoxify DON. In this study, a Bacillus licheniformis strain named YB9 with a strong ability to detoxify DON was isolated and characterized from a moldy soil sample. YB9 could degrade more than 82.67% of 1 mg/L DON within 48 h at 37 °C and showed strong survival and DON degradation rate at simulated gastric fluid. The effects of YB9 on mice with DON intragastrical administration were further investigated by biochemical and histopathological examination and the gut microbiota was analyzed by 16S rRNA Illumina sequencing technology. The results showed that DON increased the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), and creatinine (Cr), decreased those of immunoglobulin G (IgG) and IgM in serum, and resulted in severe pathological damage of the liver, kidney, and spleen. By contrast, YB9 supplementation obviously inhibited or attenuated the damages caused by DON in mice. In addition, YB9 addition repaired the DON-induced dysbiosis of intestinal flora, characterized by recovering the balance of Firmicutes and Bacteroidetes to the normal level and decreasing the abundance of the potentially harmful bacterium Turicibacter and the excessive Lactobacillus caused by DON. Taken together, DON-degrading strain YB9 might be used as potential probiotic additive for improving food and feed safety and modulating the intestinal microbial flora of humans and animals. |
| Audience | Academic |
| Author | Hou, Qiuqiu Shen, Lixin Zhang, Jian Wang, Shiwei Sun, Yanmei Guo, Qianqian Wei, Hong |
| AuthorAffiliation | 2 State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China 1 Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi’an 710069, China; wangsw@nwu.edu.cn (S.W.); HouQiuq@163.com (Q.H.); sheldonamy@139.com (Q.G.); zhangjian940706@163.com (J.Z.); sunyanmei2001@126.com (Y.S.) |
| AuthorAffiliation_xml | – name: 2 State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China – name: 1 Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi’an 710069, China; wangsw@nwu.edu.cn (S.W.); HouQiuq@163.com (Q.H.); sheldonamy@139.com (Q.G.); zhangjian940706@163.com (J.Z.); sunyanmei2001@126.com (Y.S.) |
| Author_xml | – sequence: 1 givenname: Shiwei surname: Wang fullname: Wang, Shiwei organization: Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China – sequence: 2 givenname: Qiuqiu surname: Hou fullname: Hou, Qiuqiu organization: Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China – sequence: 3 givenname: Qianqian surname: Guo fullname: Guo, Qianqian organization: Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China – sequence: 4 givenname: Jian surname: Zhang fullname: Zhang, Jian organization: Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China – sequence: 5 givenname: Yanmei surname: Sun fullname: Sun, Yanmei organization: Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China – sequence: 6 givenname: Hong surname: Wei fullname: Wei, Hong organization: State Key Laboratory of Agricultural Microbiology, College of Animal Sciences and Technology, Key Laboratory of Agricultural Animal Genetics, Breeding, and Reproduction of the Ministry of Education & Key Laboratory of Swine Genetics and Breeding of Ministry of Agriculture and Rural Affairs, Huazhong Agricultural University, Wuhan 430070, China – sequence: 7 givenname: Lixin surname: Shen fullname: Shen, Lixin organization: Key Laboratory of Resources Biology and Biotechnology in Western China, Ministry of Education, College of Life Sciences, Northwest University, Xi'an 710069, China |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/32183451$$D View this record in MEDLINE/PubMed |
| BookMark | eNpVks1uEzEUhUeoiJbSLUtkifUU_4xnxhukNqUQqRUbWLCyPPZ14sixgz1TGh6I58RpSmm88dH18eer4_u6OgoxQFW9JficMYE_jPHehUwoZpj0zYvqhOKO1m3LydEzfVyd5bzCZTFGBOleVceMkp41nJxUf-Y5ejW6GJAKBs2WKik9QnK_98VokUJXEO-3wd0pDyH6-goWSRkXFuhy753WO-W8nzLyTi8hOBvT2mX041KgX25conEJaKY2anDejdsd9jaaafdywczDCLko5dGt0ykOrqhrH5N6MDoNb6qXVvkMZ4_7afX9-tO32Zf65uvn-eziptac0LFmxGBuGfRctUMPAyEELGOqp4wBpdT2VCvNDae854xgENia1mgq9EC4AnZazfdcE9VKbpJbq7SVUTn5UIhpIVUanfYggTJh-8ay1uCmI1Rp3XCDBwEdaTjtC-vjnrWZhjUYDWFMyh9AD0-CW8pFvJMd4Vg0tADePwJS_DmVhOQqTqmklCVlnWAtY13z37Uo3yNdsLHAdAlfy4uWigZTKtriOt-7Srw5J7BPfRAsd8MkD4epXHj3vPsn-7_RYX8BPmfKHw |
| CitedBy_id | crossref_primary_10_1007_s12010_023_04712_6 crossref_primary_10_3390_applmicrobiol4010007 crossref_primary_10_1016_j_tifs_2022_04_002 crossref_primary_10_1016_j_jhazmat_2023_131172 crossref_primary_10_3390_ani12131609 crossref_primary_10_3390_toxins14120859 crossref_primary_10_47836_pjst_32_3_12 crossref_primary_10_3390_toxins15080492 crossref_primary_10_1080_07388551_2021_1873239 crossref_primary_10_3390_fermentation7040307 crossref_primary_10_3390_toxins15020085 crossref_primary_10_1016_j_jia_2023_11_038 crossref_primary_10_3390_toxins15060367 crossref_primary_10_3389_fmicb_2022_935884 crossref_primary_10_3389_fmicb_2022_993451 crossref_primary_10_1016_j_biocontrol_2022_105052 crossref_primary_10_3390_microorganisms9102127 crossref_primary_10_1016_j_foodres_2024_114275 crossref_primary_10_1007_s12223_022_00967_4 crossref_primary_10_3390_biotech12020032 crossref_primary_10_1016_j_aninu_2024_03_006 crossref_primary_10_1186_s40104_022_00746_8 crossref_primary_10_3390_microbiolres13020023 crossref_primary_10_1007_s00217_020_03607_8 crossref_primary_10_1016_j_envint_2024_108525 crossref_primary_10_1080_10408398_2021_1954598 crossref_primary_10_5187_jast_2022_e40 crossref_primary_10_18470_1992_1098_2021_4_86_103 crossref_primary_10_3390_toxins14020090 crossref_primary_10_3390_toxins14110781 crossref_primary_10_3390_foods10020221 crossref_primary_10_3390_toxins13080552 crossref_primary_10_3390_biology12020238 |
| Cites_doi | 10.1371/journal.pone.0194866 10.1016/j.apsb.2014.12.005 10.4142/jvs.2008.9.3.257 10.3390/toxins9120383 10.1016/j.toxlet.2004.04.023 10.3390/toxins9100334 10.3390/toxins5050912 10.1002/rcm.2373 10.1080/19440049.2016.1253112 10.1016/j.taap.2019.04.009 10.1097/MCG.0b013e3181ee31c3 10.3390/molecules22050691 10.1128/genomeA.00019-17 10.1371/journal.pone.0207745 10.1016/j.toxicon.2016.11.007 10.1111/jam.14352 10.3390/toxins10030114 10.3390/ijms10010001 10.1016/j.fct.2016.03.020 10.1016/j.toxicon.2018.09.005 10.1271/bbb.50571 10.1186/s12917-015-0449-y 10.1016/j.chemosphere.2017.03.129 10.3390/toxins9040130 10.1007/s12550-016-0260-z 10.1007/s00204-016-1826-4 10.1002/jat.3428 10.1111/lam.12790 10.1248/bpb.30.1808 10.1016/j.taap.2019.04.020 10.1007/s11274-011-0785-4 10.1016/j.toxlet.2008.02.005 10.1016/j.etap.2014.11.028 10.3390/toxins8110306 10.1016/j.foodres.2019.108595 10.1016/j.etap.2015.08.029 10.1016/j.toxlet.2014.12.017 |
| ContentType | Journal Article |
| Copyright | COPYRIGHT 2020 MDPI AG 2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. 2020 by the authors. 2020 |
| Copyright_xml | – notice: COPYRIGHT 2020 MDPI AG – notice: 2020. This work is licensed under http://creativecommons.org/licenses/by/3.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. – notice: 2020 by the authors. 2020 |
| DBID | CGR CUY CVF ECM EIF NPM AAYXX CITATION 3V. 7T7 7U7 7X7 7XB 88E 8FD 8FE 8FH 8FI 8FJ 8FK ABUWG AFKRA ATCPS AZQEC BBNVY BENPR BHPHI C1K CCPQU DWQXO FR3 FYUFA GHDGH GNUQQ HCIFZ K9. LK8 M0S M1P M7P P64 PATMY PIMPY PQEST PQQKQ PQUKI PYCSY 5PM DOA |
| DOI | 10.3390/toxins12030184 |
| DatabaseName | Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef ProQuest Central (Corporate) Industrial and Applied Microbiology Abstracts (Microbiology A) Toxicology Abstracts ProQuest Health & Medical Collection ProQuest Central (purchase pre-March 2016) Medical Database (Alumni Edition) Technology Research Database ProQuest SciTech Collection ProQuest Natural Science Collection Hospital Premium Collection Hospital Premium Collection (Alumni Edition) ProQuest Central (Alumni) (purchase pre-March 2016) ProQuest Central (Alumni) ProQuest Central UK/Ireland Agricultural & Environmental Science Collection ProQuest Central Essentials Biological Science Collection AUTh Library subscriptions: ProQuest Central ProQuest Natural Science Collection Environmental Sciences and Pollution Management ProQuest One Community College ProQuest Central Engineering Research Database Health Research Premium Collection Health Research Premium Collection (Alumni) ProQuest Central Student SciTech Premium Collection (Proquest) (PQ_SDU_P3) ProQuest Health & Medical Complete (Alumni) Biological Sciences Health & Medical Collection (Alumni Edition) PML(ProQuest Medical Library) Biological Science Database Biotechnology and BioEngineering Abstracts Environmental Science Database Publicly Available Content Database ProQuest One Academic Eastern Edition (DO NOT USE) ProQuest One Academic ProQuest One Academic UKI Edition Environmental Science Collection PubMed Central (Full Participant titles) DOAJ Directory of Open Access Journals |
| DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef Publicly Available Content Database ProQuest Central Student Technology Research Database ProQuest Central Essentials ProQuest Health & Medical Complete (Alumni) ProQuest Central (Alumni Edition) SciTech Premium Collection ProQuest One Community College ProQuest Natural Science Collection Environmental Sciences and Pollution Management ProQuest Central Health Research Premium Collection Health and Medicine Complete (Alumni Edition) Natural Science Collection ProQuest Central Korea Agricultural & Environmental Science Collection Biological Science Collection Industrial and Applied Microbiology Abstracts (Microbiology A) ProQuest Medical Library (Alumni) ProQuest Biological Science Collection Toxicology Abstracts ProQuest One Academic Eastern Edition ProQuest Hospital Collection Health Research Premium Collection (Alumni) Biological Science Database ProQuest SciTech Collection ProQuest Hospital Collection (Alumni) Biotechnology and BioEngineering Abstracts Environmental Science Collection ProQuest Health & Medical Complete ProQuest Medical Library ProQuest One Academic UKI Edition Environmental Science Database Engineering Research Database ProQuest One Academic ProQuest Central (Alumni) |
| DatabaseTitleList | MEDLINE CrossRef Publicly Available Content Database |
| Database_xml | – sequence: 1 dbid: DOA name: DOAJ Directory of Open Access Journals url: https://www.doaj.org/ sourceTypes: Open Website – sequence: 2 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 3 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database – sequence: 4 dbid: BENPR name: AUTh Library subscriptions: ProQuest Central url: https://www.proquest.com/central sourceTypes: Aggregation Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Anatomy & Physiology |
| EISSN | 2072-6651 |
| ExternalDocumentID | oai_doaj_org_article_e239f84f36d04712acc45d0b9e714528 A629402296 10_3390_toxins12030184 32183451 |
| Genre | Research Support, Non-U.S. Gov't Journal Article |
| GeographicLocations | China |
| GeographicLocations_xml | – name: China |
| GrantInformation_xml | – fundername: he Provincial Natural Science Foundation of Shaanxi Province grantid: 2018ZDXM-SF-004 – fundername: Chinese National key R & D projects grantid: 2017YFD0500503 and 2017YFD0501000 – fundername: National Natural Science Foundation of China grantid: 81770434, 31770152, and 31400094 |
| GroupedDBID | --- 2XV 3V. 53G 5VS 7X7 7XC 88E 8FE 8FH 8FI 8FJ A8Z AADQD AAHBH ABDBF ABUWG ACGFO ACPRK ADBBV AEGXH AENEX AFKRA AFRAH AFZYC AIAGR ALIPV ALMA_UNASSIGNED_HOLDINGS AOIJS ATCPS BAWUL BBNVY BCNDV BENPR BHPHI BPHCQ BVXVI CCPQU CGR CUY CVF DIK E3Z EBD ECM EIF EMOBN ESTFP ESX F5P FYUFA GROUPED_DOAJ GX1 HCIFZ HH5 HMCUK HYE IAO IHR KQ8 LK8 M1P M48 M7P MODMG M~E NPM OK1 PATMY PGMZT PIMPY PQQKQ PROAC PSQYO PYCSY RIG RNS RPM SV3 TR2 TUS UKHRP AAYXX CITATION ITC 7T7 7U7 7XB 8FD 8FK AZQEC C1K DWQXO FR3 GNUQQ K9. P64 PQEST PQUKI 5PM |
| ID | FETCH-LOGICAL-c512t-31d05f3e85a6b8eb111ef33a8233e222f82cac5d52585310e90fd6dc29cb15ae3 |
| IEDL.DBID | RPM |
| ISSN | 2072-6651 |
| IngestDate | Tue Oct 22 15:13:21 EDT 2024 Tue Sep 17 21:19:52 EDT 2024 Sat Nov 09 07:45:27 EST 2024 Fri Feb 23 00:01:08 EST 2024 Thu Sep 26 21:31:41 EDT 2024 Sat Sep 28 08:38:34 EDT 2024 |
| IsDoiOpenAccess | true |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 3 |
| Keywords | deoxynivalenol degradation and detoxification intestinal microbial flora Bacillus licheniformis YB9 |
| Language | English |
| License | Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c512t-31d05f3e85a6b8eb111ef33a8233e222f82cac5d52585310e90fd6dc29cb15ae3 |
| Notes | Equal contributions to this work. |
| OpenAccessLink | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7150942/ |
| PMID | 32183451 |
| PQID | 2379363374 |
| PQPubID | 2032321 |
| ParticipantIDs | doaj_primary_oai_doaj_org_article_e239f84f36d04712acc45d0b9e714528 pubmedcentral_primary_oai_pubmedcentral_nih_gov_7150942 proquest_journals_2379363374 gale_infotracmisc_A629402296 crossref_primary_10_3390_toxins12030184 pubmed_primary_32183451 |
| PublicationCentury | 2000 |
| PublicationDate | 20200315 |
| PublicationDateYYYYMMDD | 2020-03-15 |
| PublicationDate_xml | – month: 3 year: 2020 text: 20200315 day: 15 |
| PublicationDecade | 2020 |
| PublicationPlace | Switzerland |
| PublicationPlace_xml | – name: Switzerland – name: Basel |
| PublicationTitle | Toxins |
| PublicationTitleAlternate | Toxins (Basel) |
| PublicationYear | 2020 |
| Publisher | MDPI AG MDPI |
| Publisher_xml | – name: MDPI AG – name: MDPI |
| References | Ren (ref_18) 2015; 39 Islam (ref_26) 2012; 28 Tardivel (ref_12) 2015; 232 Wang (ref_35) 2018; 155 Delmulle (ref_2) 2006; 20 Gajecka (ref_7) 2017; 125 Wan (ref_25) 2019; 126 Wache (ref_22) 2009; 10 ref_14 Zhao (ref_28) 2016; 92 ref_13 Ahad (ref_27) 2017; 5 Kim (ref_16) 2008; 9 DelPiano (ref_34) 2010; 44 ref_31 Liang (ref_9) 2015; 40 Springler (ref_5) 2017; 33 ref_17 Park (ref_24) 2006; 70 Peng (ref_11) 2019; 374 ref_37 Peng (ref_10) 2017; 37 Wang (ref_36) 2017; 65 Wang (ref_32) 2017; 34 Payros (ref_23) 2016; 90 Wang (ref_33) 2019; 372 Moon (ref_21) 2007; 30 Awad (ref_19) 2013; 5 Cao (ref_30) 2019; 127 Pestka (ref_20) 2004; 153 Pestka (ref_15) 2008; 178 ref_3 Ji (ref_8) 2017; 180 ref_29 Wang (ref_1) 2015; 5 ref_4 ref_6 |
| References_xml | – ident: ref_31 doi: 10.1371/journal.pone.0194866 – volume: 5 start-page: 38 year: 2015 ident: ref_1 article-title: Safety issues and new rapid detection methods in traditional Chinese medicinal materials publication-title: Acta Pharm. Sin. B doi: 10.1016/j.apsb.2014.12.005 contributor: fullname: Wang – volume: 9 start-page: 257 year: 2008 ident: ref_16 article-title: Plasma haptoglobin and immunoglobulins as diagnostic indicators of deoxynivalenol intoxication publication-title: J. Vet. Sci. doi: 10.4142/jvs.2008.9.3.257 contributor: fullname: Kim – ident: ref_14 doi: 10.3390/toxins9120383 – volume: 153 start-page: 61 year: 2004 ident: ref_20 article-title: Cellular and molecular mechanisms for immune modulation by deoxynivalenol and other trichothecenes: Unraveling a paradox publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2004.04.023 contributor: fullname: Pestka – ident: ref_4 doi: 10.3390/toxins9100334 – volume: 5 start-page: 912 year: 2013 ident: ref_19 article-title: The toxicological impacts of the Fusarium mycotoxin, deoxynivalenol, in poultry flocks with special reference to immunotoxicity publication-title: Toxins doi: 10.3390/toxins5050912 contributor: fullname: Awad – volume: 20 start-page: 771 year: 2006 ident: ref_2 article-title: Development of a liquid chromatography/tandem mass spectrometry method for the simultaneous determination of 16 mycotoxins on cellulose filters and in fungal cultures publication-title: Rapid Commun. Mass Spectrom. doi: 10.1002/rcm.2373 contributor: fullname: Delmulle – volume: 34 start-page: 103 year: 2017 ident: ref_32 article-title: In vivo toxicity assessment of deoxynivalenol-contaminated wheat after ozone degradation publication-title: Food Addit. Contam. Part A Chem. Anal. Control Expo. Risk Assess. doi: 10.1080/19440049.2016.1253112 contributor: fullname: Wang – volume: 372 start-page: 47 year: 2019 ident: ref_33 article-title: Metagenomic analysis of gut microbiota alteration in a mouse model exposed to mycotoxin deoxynivalenol publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2019.04.009 contributor: fullname: Wang – volume: 44 start-page: S30 year: 2010 ident: ref_34 article-title: The use of probiotics in healthy volunteers with evacuation disorders and hard stools: A double-blind, randomized, placebo-controlled study publication-title: J. Clin. Gastroenterol. doi: 10.1097/MCG.0b013e3181ee31c3 contributor: fullname: DelPiano – ident: ref_6 doi: 10.3390/molecules22050691 – volume: 5 start-page: e17 year: 2017 ident: ref_27 article-title: Draft genome sequence of Citrobacter freundii strain A47, resistant to the mycotoxin deoxynivalenol publication-title: Genome Announc. doi: 10.1128/genomeA.00019-17 contributor: fullname: Ahad – ident: ref_37 doi: 10.1371/journal.pone.0207745 – volume: 125 start-page: 32 year: 2017 ident: ref_7 article-title: Changes in the metabolic profile and body weight of pre-pubertal gilts during prolonged monotonic exposure to low doses of zearalenone and deoxynivalenol publication-title: Toxicon doi: 10.1016/j.toxicon.2016.11.007 contributor: fullname: Gajecka – volume: 127 start-page: 880 year: 2019 ident: ref_30 article-title: Bacillus licheniformis, a potential probiotic, inhibits obesity by modulating colonic microflora in C57BL/6J mice model publication-title: J. Appl. Microbiol. doi: 10.1111/jam.14352 contributor: fullname: Cao – ident: ref_17 doi: 10.3390/toxins10030114 – volume: 10 start-page: 1 year: 2009 ident: ref_22 article-title: Impact of deoxynivalenol on the intestinal microflora of pigs publication-title: Int. J. Mol. Sci. doi: 10.3390/ijms10010001 contributor: fullname: Wache – volume: 92 start-page: 143 year: 2016 ident: ref_28 article-title: Protective effect of Devosia sp. ANSB714 on growth performance, serum chemistry, immunity function and residues in kidneys of mice exposed to deoxynivalenol publication-title: Food Chem. Toxicol doi: 10.1016/j.fct.2016.03.020 contributor: fullname: Zhao – volume: 155 start-page: 9 year: 2018 ident: ref_35 article-title: Isolation and characterization of the Bacillus cereus BC7 strain, which is capable of zearalenone removal and intestinal flora modulation in mice publication-title: Toxicon doi: 10.1016/j.toxicon.2018.09.005 contributor: fullname: Wang – volume: 70 start-page: 1764 year: 2006 ident: ref_24 article-title: Effect of cooking process on the deoxynivalenol content and its subsequent cytotoxicity in wheat products publication-title: Biosci. Biotechnol. Biochem. doi: 10.1271/bbb.50571 contributor: fullname: Park – ident: ref_13 doi: 10.1186/s12917-015-0449-y – volume: 180 start-page: 267 year: 2017 ident: ref_8 article-title: The disorder metabolic profiling in kidney and spleen of mice induced by mycotoxins deoxynivalenol through gas chromatography mass spectrometry publication-title: Chemosphere doi: 10.1016/j.chemosphere.2017.03.129 contributor: fullname: Ji – ident: ref_29 doi: 10.3390/toxins9040130 – volume: 33 start-page: 25 year: 2017 ident: ref_5 article-title: Deoxynivalenol and its metabolite deepoxy-deoxynivalenol: Multi-parameter analysis for the evaluation of cytotoxicity and cellular effects publication-title: Mycotoxin Res. doi: 10.1007/s12550-016-0260-z contributor: fullname: Springler – volume: 90 start-page: 2931 year: 2016 ident: ref_23 article-title: Toxicology of deoxynivalenol and its acetylated and modified forms publication-title: Arch. Toxicol. doi: 10.1007/s00204-016-1826-4 contributor: fullname: Payros – volume: 37 start-page: 518 year: 2017 ident: ref_10 article-title: Current sights for mechanisms of deoxynivalenol-induced hepatotoxicity and prospective views for future scientific research: A mini review publication-title: J. Appl. Toxicol. doi: 10.1002/jat.3428 contributor: fullname: Peng – volume: 65 start-page: 414 year: 2017 ident: ref_36 article-title: Isolation and characterization of a novel deoxynivalenol-transforming strain paradevosia shaoguanensis DDB001 from wheat field soil publication-title: Lett. Appl. Microbiol. doi: 10.1111/lam.12790 contributor: fullname: Wang – volume: 30 start-page: 1808 year: 2007 ident: ref_21 article-title: Toxic alterations in chick embryonic liver and spleen by acute exposure to Fusarium-producing mycotoxin deoxynivalenol publication-title: Biol. Pharm. Bull. doi: 10.1248/bpb.30.1808 contributor: fullname: Moon – volume: 374 start-page: 20 year: 2019 ident: ref_11 article-title: Heme oxygenase-1 attenuates low-dose of deoxynivalenol-induced liver inflammation potentially associating with microbiota publication-title: Toxicol. Appl. Pharmacol. doi: 10.1016/j.taap.2019.04.020 contributor: fullname: Peng – volume: 28 start-page: 7 year: 2012 ident: ref_26 article-title: Aerobic and anaerobic de-epoxydation of mycotoxin deoxynivalenol by bacteria originating from agricultural soil publication-title: World J. Microbiol. Biotechnol. doi: 10.1007/s11274-011-0785-4 contributor: fullname: Islam – volume: 178 start-page: 83 year: 2008 ident: ref_15 article-title: Immunochemical assessment of deoxynivalenol tissue distribution following oral exposure in the mouse publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2008.02.005 contributor: fullname: Pestka – volume: 39 start-page: 339 year: 2015 ident: ref_18 article-title: Deoxynivalenol induces apoptosis in chicken splenic lymphocytes via the reactive oxygen species-mediated mitochondrial pathway publication-title: Environ. Toxicol. Pharmacol. doi: 10.1016/j.etap.2014.11.028 contributor: fullname: Ren – ident: ref_3 doi: 10.3390/toxins8110306 – volume: 126 start-page: 108595 year: 2019 ident: ref_25 article-title: Modulation of gut microbiota by ilex kudingcha improves dextran sulfate sodium-induced colitis publication-title: Food Res. Int. doi: 10.1016/j.foodres.2019.108595 contributor: fullname: Wan – volume: 40 start-page: 686 year: 2015 ident: ref_9 article-title: Individual and combined effects of deoxynivalenol and zearalenone on mouse kidney publication-title: Environ. Toxicol. Pharmacol. doi: 10.1016/j.etap.2015.08.029 contributor: fullname: Liang – volume: 232 start-page: 601 year: 2015 ident: ref_12 article-title: The food born mycotoxin deoxynivalenol induces low-grade inflammation in mice in the absence of observed-adverse effects publication-title: Toxicol. Lett. doi: 10.1016/j.toxlet.2014.12.017 contributor: fullname: Tardivel |
| SSID | ssj0000331917 |
| Score | 2.454479 |
| Snippet | Deoxynivalenol (DON) is one of the most prevalent food- and feed-associated mycotoxins. It frequently contaminates agricultural commodities and poses serious... |
| SourceID | doaj pubmedcentral proquest gale crossref pubmed |
| SourceType | Open Website Open Access Repository Aggregation Database Index Database |
| StartPage | 184 |
| SubjectTerms | Agricultural commodities Alanine Alanine transaminase Alanine Transaminase - blood Animal health Animals Aspartate aminotransferase Aspartate Aminotransferases - blood Bacillus Bacillus licheniformis Bacillus licheniformis - isolation & purification Bacillus licheniformis - metabolism bacillus licheniformis yb9 Bacteria Biodegradation Biodegradation, Environmental Colon - drug effects Colon - microbiology Colon - pathology Commodities Creatinine Damage degradation and detoxification Deoxynivalenol Dietary Supplements Dysbacteriosis Dysbiosis - blood Dysbiosis - prevention & control Economic conditions Economic impact Flora Food Food additives Food safety Gastrointestinal Microbiome - drug effects IgG antibody Immunoglobulin G Immunoglobulin G - blood Immunoglobulin M intestinal microbial flora Intestinal microflora Intestine Investigations Kidneys Liver Liver - drug effects Liver - microbiology Liver - pathology Mice, Inbred BALB C Microbiota Microbiota (Symbiotic organisms) Microorganisms Morphology Mycotoxins Phylogenetics Physiological aspects Probiotics Probiotics - pharmacology rRNA 16S Soil contamination Soil Microbiology Spleen Trichothecenes - analysis Trichothecenes - toxicity |
| SummonAdditionalLinks | – databaseName: DOAJ Directory of Open Access Journals dbid: DOA link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwrV09b9swECWKTF2Ktklbt0nBoWgnIRIpSuJoOzHSAO7UAOkk8BMVoFBBbQPxH-rvzB3pGBYydOkmWIRw5j3e3SOOj4R80ZD0jZI-s5azrBS1zhRk8syxxnNjGkjqeN55-aO6uimvb8XtwVVf2BOW5IHTxJ07xqVvSs8rm0MgZcqYUthcS1cXpWDpmG8uD8hUjMGcIxFJKo0ceP35enjowqpgSAGacpSFolj_85B8kJPG_ZIHCWjxmrzaVY50mix-Q1648JYcTwOw5rst_UpjL2fcJD8mf78DpOKcUxUsne9VmdOhSzp4quiFGx62oQOouTD02QXKRmAmo7M0dnOHT13fb1a0x47RgKe4ABf010xS3MClUD3SOaTb2GG7xc8uBxsvBIPP4GYjBBA0etlFvSd4WvSAuTgQItQJuVlc_pxfZbsbGTIDhcEaArbNheeuEarSDYT5onCec9Uwzh1UGr5hRhlhBQMWAoWjk7m3lTVMGl0I5fg7chSG4D4Q6ovG6hrYjqk4-LFWRgH1K3LtvQaKpibk25OH2vskvNECYUFftmNfTsgMHbgfhYLZ8QeAUbuDUfsvGE3IKbq_xWUNPjYwmaadVkwCv2aygtdPsGh3i3zVMg7BreK8BhPeJ4TsjeBYepaimJB6hJ2RleM3ofsd5b3rAkUN2cf_8bc-kZcMNwiwAVGckqP1n407gypqrT_HBfMICUsd5A priority: 102 providerName: Directory of Open Access Journals – databaseName: ProQuest Health & Medical Collection dbid: 7X7 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Nb9QwELWgXLig0vIRWpAPCE5REztOnBPa3bIqSMuJSsspcvwBkVKndHel7h_q7-yMk10aVeIWbazEyjzPzJsdPxPysYagr1XpYmM4izNR1LGCSB5bJh3XWkJQx_3Oix_5xWX2fSmWQ8FtNbRV7nxicNSm01gjP2MckJRzXmRfrv_GeGoU_rs6HKHxlDxLWZJjS1exLPY1loRzpCO9ViMHdn-27m4bv4KxgGuZjWJRkOx_7JgfRKZx1-SDMDQ_JC-G_JFOeoO_JE-sPyLHEw_c-WpLP9HQ0RlK5cfk7hsAK3x5qryhs702c7_1knaOKnpuu9utbwBw1ndtfI7iERjP6LQfu7nCq6ZtNyvaYt-ox71cgA76a1pSLONSyCHpDIJu6LPd4mMXnQnHgsFjsOQIbgQnvWiC6hNczVtAXhgIfuoVuZx__Tm7iIdzGWIN6cEa3LZJhONWCpXXEpx9mlrHuZKMcwv5hpNMKy2MYMBFIH20ZeJMbjQrdZ0KZflrcuA7b98S6lJp6gI4j855JlihtAICmCa1czUQNRWRzzsLVde9_EYFtAVtWY1tGZEpGnA_CmWzww_dze9qWIWVZbx0MnM8NwlEZaa0zoRJ6tIWKbxeRuQUzV_h4gYba_iYuprkrASWzcocbu9gUQ1LfVX9A2ZE3vQI2U-CYwKaiTQixQg7o1mO7_jmTxD5LlKUNmTv_v_KE_KcYQEAGwzFKTlY32zse8iS1vWHsBTuAbp2Fgw priority: 102 providerName: ProQuest – databaseName: Scholars Portal Journals (Open Access) dbid: M48 link: http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lj9MwELZguXBBwPIoLMgHBKdAYseOc0Co7VItSOVEpeUUOX5ApawDfUjtH-J3MuOkZSNW3KLGckeZz_PNZ43HhLyqgfSNLn1iLWdJLoo60cDkiWPKc2MUkDqed55_kReL_POluPxb_9R_wPWN0g7vk1qsmre7X_sPsODfo-IEyf5u0-6WYZ0xzO5VfpvcYTmodCzj61P9GJU5R2mCd82lBUukFFnXw_GGKQYcFVv5_xuwrzHWsJryGj3N7pN7fV5Jxx0QHpBbLjwkp-MAmvpqT1_TWOkZt9BPye9PALjoEaqDpdNjz-buSCZtPdX03LW7fVgCEF1om-Qcm0ogz9FJN3Z7hU_LptmuaYP1pAHPeAFq6LdJSXF7l0JuSadAxrH-do_TzlsbrwuDaXArEsILGj1fxm5Q8DRrAJFxIMSvR2Qx-_h1epH09zUkBtKGDYRzmwrPnRJa1gpIIMuc51wrxrmDPMQrZrQRVjDQKJBWujL1VlrDSlNnQjv-mJyENrinhPpM2boALWQkzwUrtNEgDLO09r4GAadH5M3BQ9XPri1HBXIGfVkNfTkiE3TgcRS2044_tKvvVb86K8d46VXuubQpsDXTxuTCpnXpigz-Xo3IGbq_QhiCjw18TFONJStBfbNSwusDLKoDgivGIfRJzgsw4UmHkKMRHBPTXGQjUgywM7By-CYsf8Tm30WGLQ_Zs_9b9JzcZbgxgIWH4oycbFZb9wKyp039Mi6LP28JGys priority: 102 providerName: Scholars Portal |
| Title | Isolation and Characterization of a Deoxynivalenol-Degrading Bacterium Bacillus licheniformis YB9 with the Capability of Modulating Intestinal Microbial Flora of Mice |
| URI | https://www.ncbi.nlm.nih.gov/pubmed/32183451 https://www.proquest.com/docview/2379363374 https://pubmed.ncbi.nlm.nih.gov/PMC7150942 https://doaj.org/article/e239f84f36d04712acc45d0b9e714528 |
| Volume | 12 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1Lb9swDBba7rLLsK57ZOsCHYbt5CaWLFs-JmmDbkCKYliB7GTIeqwGHLloEqD5Q_udJeUkiLHbLoZhyzZhfiL5ERRFyJcSnL5WuYuM4SxKRFZGCjx5ZJl0XGsJTh3XO89u0uu75MdczI-I2K2FCUX7uqwufL248NV9qK18WOjBrk5scDubZDG2fWODY3IMAD2g6MH8co4cpG3QyIHSD1bNU-WXMcPoX-JGPBzjgkTEHV8UWvb_a5gPPFO3avLADU1fk1fb-JGOWjlPyZH1b8jZyAN3XmzoVxoqOkOq_Iz8_Q7ACn-eKm_oZN-buV16SRtHFb20zdPGVwA465s6usTmEejP6Lgdu17gWVXX6yWtsW7U41ouQAf9Pc4ppnEpxJB0Ak431Nlu8LWzxoRtweA1mHIEM4JCz6rQ9QnOpjUgLwwEO_WW3E2vfk2uo-2-DJGG8GAFZtsMheNWCpWWEox9HFvHuZKMcwvxhpNMKy2MYMBFIHy0-dCZ1GiW6zIWyvJ35MQ33n4g1MXSlBlwHp2CQlimtAICGA9L50ogaqpHvu00VDy07TcKoC2o1qKr1h4ZowL3o7BtdrjQPP4ptuApLOO5k4njqRmCV2ZK60SYYZnbLIbPyx45R_UXOLlBxxp-pi5GKcuBZbM8hds7WBTbqb4sGAcTl3KegQjvW4TshdgBrUeyDnY6UnbvAOZDk-8txj_-95OfyEuGuQGsPRTn5GT1uLafIYBalX2YNvOsT16Mr25uf_ZDGgKOs0T2w1R6BtJKIzo |
| link.rule.ids | 230,315,730,783,787,867,888,2109,2228,12068,21400,24330,27936,27937,31731,33756,43322,43817,53804,53806,74073,74630 |
| linkProvider | National Library of Medicine |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagHOCCgPIIFPABwSlqYseJc0K7W1Zb6PbUSsspcvyAlVKndHel7h_idzLjZJdGSNyixEosz3hmvsn4G0I-1OD0tSpdbAxncSaKOlbgyWPLpONaS3DqeN55fp7PLrOvC7HoE26rvqxyZxODoTatxhz5MeOgSTnnRfb5-leMXaPw72rfQuM-eYA8XNjBoFgU-xxLwjnCkY6rkQO6P163t0u_ShkCAZkNfFGg7P_XMN_xTMOqyTtuaPqEPO7jRzrqBP6U3LP-GTkcecDOV1v6kYaKzpAqPyS_T0GxwspT5Q2d7LmZu6OXtHVU0RPb3m79EhTO-raJT5A8Av0ZHXdjN1d4tWyazYo2WDfq8SwXaAf9Pi4ppnEpxJB0Ak431Nlu8bXz1oS2YPAaTDmCGcFJz5eB9Qmupg1oXhgIduo5uZx-uZjM4r4vQ6whPFiD2TaJcNxKofJagrFPU-s4V5JxbiHecJJppYURDLAIhI-2TJzJjWalrlOhLH9BDnzr7StCXSpNXQDm0TnPBCuUVgAA06R2rgagpiLyaSeh6rqj36gAtqAsq6EsIzJGAe5HIW12uNHe_Kj6XVhZxksnM8dzk4BXZkrrTJikLm2RwudlRI5Q_BVubpCxhsXU1ShnJaBsVubweKcWVb_VV9VfxYzIy05D9pPgGIBmIo1IMdCdwSyHT_zyZyD5LlKkNmSv___J9-Th7GJ-Vp2dnn97Qx4xTAZgsaE4Igfrm419CxHTun4XtsUf28oY8w |
| linkToPdf | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwfV1Lb9QwELagSIgLAsojbQEfEJyiTew4jxPaB6sW2IoDlZZT5PhRIqVO6e5K3T_E72TGyS6NkLhZiZVYmW8e32Q8JuRdBU5fycKGWnMWJiKrQgmePDQst1ypHJw67ndenKenF8nnpVj29U-rvqxyZxO9odatwhz5iHFAUsp5loxsXxbxbTb_eP0rxBOk8E9rf5zGffIgA5aCmM-W2T7fEnGO1KTr28iB6Y_W7W3tVjFDUpAnA7_k2_f_a6TveKlhBeUdlzR_Qh73sSQdd8J_Su4Z94wcjh3w6KstfU99dadPmx-S32cAMi8FKp2m032f5m4bJm0tlXRm2tutqwF8xrVNOMNGEujb6KSbu7nCUd00mxVtsIbU4b4uQAr9MSkopnQpxJN0Cg7Y19xu8bGLVvsjwuAxmH4Ek4KLXtS-AxSM5g2g0E8Em_WcXMw_fZ-ehv0ZDaGCUGENJlxHwnKTC5lWORj-ODaWc5kzzg3EHjZnSiqhBQNeAqGkKSKrU61YoapYSMNfkAPXOvOKUBvnusqA_6iUJ4JlUkkgg3FUWVsBaZMB-bCTUHndteIogcKgLMuhLAMyQQHuZ2ELbX-hvbkse40sDeOFzRPLUx2Bh2ZSqUToqCpMFsPr84CcoPhLVHSQsYKPqcpxygpg3KxI4fYOFmWv9qvyL0gD8rJDyH4RHIPRRMQByQbYGaxyeMfVP33D7yzGNofs6P-vfEsegkaUX8_OvxyTRwzzAlh3KE7IwfpmY15D8LSu3nit-APg8x0r |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Isolation+and+Characterization+of+a+Deoxynivalenol-Degrading+Bacterium+Bacillus+licheniformis+YB9+with+the+Capability+of+Modulating+Intestinal+Microbial+Flora+of+Mice&rft.jtitle=Toxins&rft.au=Wang%2C+Shiwei&rft.au=Hou%2C+Qiuqiu&rft.au=Guo%2C+Qianqian&rft.au=Zhang%2C+Jian&rft.date=2020-03-15&rft.pub=MDPI+AG&rft.issn=2072-6651&rft.eissn=2072-6651&rft.volume=10&rft.issue=3&rft.spage=1&rft_id=info:doi/10.3390%2Ftoxins12030184&rft.externalDocID=A629402296 |
| thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=2072-6651&client=summon |
| thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=2072-6651&client=summon |
| thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=2072-6651&client=summon |