Modulation of Autophagy in Cancer Cells by Dietary Polyphenols

• Published in: Antioxidants Vol. 10; no. 1; p. 123
• Main Authors: Musial, Claudia, Siedlecka-Kroplewska, Kamila, Kmiec, Zbigniew, Gorska-Ponikowska, Magdalena
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 01.01.2021; MDPI
• Subjects: Angiogenesis; Animal models; Antioxidants; apigenin; Apoptosis; Autophagy; Cancer; cancer cells; Cancer therapies; Cell cycle; Cell death; Cell growth; Chemoresistance; Chemotherapy; Colorectal cancer; Curcumin; dietary polyphenols; Enzymes; epigallocatechin gallate; Epigallocatechin-3-gallate; Homeostasis; Hypoxia; Inflammation; Kinases; Lung cancer; Metabolism; oleuropein; Oxidative stress; Phagocytosis; Polyphenols; Proteins; Reactive oxygen species; Resveratrol; Review; Reviews; Tumor microenvironment; Tumors; autophagy; epigallocatechin gallate; apigenin; cancer cells; oleuropein; flavonoids; resveratrol; dietary polyphenols; pterostilbene; punicalgin

The role of autophagy is to degrade damaged or unnecessary cellular structures. Both in vivo and in vitro studies suggest a dual role of autophagy in cancer-it may promote the development of neoplasms, but it may also play a tumor protective function. The mechanism of autophagy depends on the geneti...