Telomere length in small‐for‐gestational‐age babies

• Published in: BJOG : an international journal of obstetrics and gynaecology Vol. 113; no. 3; pp. 318 - 323
• Main Authors: Akkad, A, Hastings, R, Konje, JC, Bell, SC, Thurston, H, Williams, B
• Format: Journal Article
• Language: English
• Published: Oxford, UK Blackwell Publishing Ltd 01.03.2006; Blackwell
• Subjects: Adult; Biological and medical sciences; Blotting, Southern; Case-Control Studies; Chromosome Disorders - genetics; Chromosome Disorders - pathology; Cohort Studies; Diseases of mother, fetus and pregnancy; Female; Fetal Blood - chemistry; Fetal growth restriction; Fetal Growth Retardation - blood; Fetal Growth Retardation - genetics; Fetal Growth Retardation - pathology; Fetal origins; Gestational Age; Gynecology. Andrology. Obstetrics; Humans; Infant, Newborn; Infant, Small for Gestational Age - blood; Infant, Small for Gestational Age - physiology; Male; Medical sciences; Parity; Pregnancy; Pregnancy. Fetus. Placenta; Prospective Studies; small for gestational age; Telomere - pathology; telomere shortening; Human; Fetal diseases; Intrauterine growth retardation; Pregnancy disorders; Length; Gynecology; Infant; Obstetrics; Telomere

Objective  Short telomeres are associated with adult cardiovascular disease. Our aim was to determine whether small‐for‐gestational‐age (SGA) newborns have shortened telomeres compared with appropriately grown controls. Design  Prospective cohort study. Setting  Large tertiary referral unit in Trent...