Tramadol-Induced Mood Elevation in a Patient with No Previous Psychiatric History

Tramadol is a powerful analgesic medication with antidepressant effects like venlafaxine. Hypomanic features were reported in patients with psychiatric history of mood disturbance when tramadol was prescribed for them. However, it is extremely rare to notice such mood-elevating effect in patients wh...

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Published inCase reports in psychiatry Vol. 2018; no. 2018; pp. 1 - 3
Main Authors Osman, Mugtaba, Mustafa, Mashael
Format Journal Article
LanguageEnglish
Published Cairo, Egypt Hindawi Publishing Corporation 2018
Hindawi
John Wiley & Sons, Inc
Hindawi Limited
Subjects
Antidepressants
Case Report
Case reports
Delirium
Drug dosages
Drug therapy
Emotional disorders
Medical research
Narcotics
Pain
Patients
Pharmacology
Psychopharmacology
Serotonin
Tramadol
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Abstract Tramadol is a powerful analgesic medication with antidepressant effects like venlafaxine. Hypomanic features were reported in patients with psychiatric history of mood disturbance when tramadol was prescribed for them. However, it is extremely rare to notice such mood-elevating effect in patients who have no previous psychiatric history. We report on the observation of a distressing mood-elevating effect for tramadol in a patient with no previous psychiatric history. We present the case of a 26-year-old female patient who developed accelerated flow of speech, overactivity, and difficulty in sleeping following intake of tramadol 50 mg dose. These symptoms resolved four hours later and recurred as she retook tramadol. The patient has no history of mood disorder or any other psychiatric comorbidity. Clinicians should exercise caution when prescribing tramadol.
AbstractList Tramadol is a powerful analgesic medication with antidepressant effects like venlafaxine. Hypomanic features were reported in patients with psychiatric history of mood disturbance when tramadol was prescribed for them. However, it is extremely rare to notice such mood-elevating effect in patients who have no previous psychiatric history. We report on the observation of a distressing mood-elevating effect for tramadol in a patient with no previous psychiatric history. We present the case of a 26-year-old female patient who developed accelerated flow of speech, overactivity, and difficulty in sleeping following intake of tramadol 50 mg dose. These symptoms resolved four hours later and recurred as she retook tramadol. The patient has no history of mood disorder or any other psychiatric comorbidity. Clinicians should exercise caution when prescribing tramadol.
Audience Academic
Author Osman, Mugtaba
Mustafa, Mashael
AuthorAffiliation 1 Armed Forces Centre for Psychiatric Care, Armed Forces Hospital in Taif Region, Taif, Saudi Arabia
2 Armed Forces Centre for Health Rehabilitation in Taif, Armed Forces Hospital in Taif Region, Taif, Saudi Arabia
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  fullname: Osman, Mugtaba
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  fullname: Mustafa, Mashael
BackLink https://www.ncbi.nlm.nih.gov/pubmed/30364082$$D View this record in MEDLINE/PubMed
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CitedBy_id crossref_primary_10_1016_j_mehy_2020_110468
crossref_primary_10_1186_s43045_023_00374_6
crossref_primary_10_4236_ajac_2021_128018
crossref_primary_10_1021_acsptsci_0c00132
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Copyright Copyright © 2018 Mugtaba Osman and Mashael Mustafa.
COPYRIGHT 2018 John Wiley & Sons, Inc.
Copyright © 2018 Mugtaba Osman and Mashael Mustafa. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0
Copyright © 2018 Mugtaba Osman and Mashael Mustafa. 2018
Copyright_xml – notice: Copyright © 2018 Mugtaba Osman and Mashael Mustafa.
– notice: COPYRIGHT 2018 John Wiley & Sons, Inc.
– notice: Copyright © 2018 Mugtaba Osman and Mashael Mustafa. This is an open access article distributed under the Creative Commons Attribution License (the “License”), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License. https://creativecommons.org/licenses/by/4.0
– notice: Copyright © 2018 Mugtaba Osman and Mashael Mustafa. 2018
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SubjectTerms Antidepressants
Case Report
Case reports
Delirium
Drug dosages
Drug therapy
Emotional disorders
Medical research
Narcotics
Pain
Patients
Pharmacology
Psychopharmacology
Serotonin
Tramadol
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Title Tramadol-Induced Mood Elevation in a Patient with No Previous Psychiatric History
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