Low Counts of Faecalibacterium prausnitzii in Colitis Microbiota

• Published in: Inflammatory bowel diseases Vol. 15; no. 8; pp. 1183 - 1189
• Main Authors: Sokol, H., Seksik, P., Furet, J. P., Firmesse, O., Nion-Larmurier, I., Beaugerie, L., Cosnes, J., Corthier, G., Marteau, P., Doré, J.
• Format: Journal Article
• Language: English
• Published: Oxford, UK Oxford University Press 01.08.2009; Wiley Subscription Services, Inc., A Wiley Company; Lippincott, Williams & Wilkins
• Subjects: Adult; Case-Control Studies; Chemical Sciences; Clostridium coccoides; Clostridium leptum; colitis; Colitis, Ulcerative - microbiology; Colitis, Ulcerative - pathology; Colon - microbiology; Colon - pathology; Colony Count, Microbial; Crohn Disease - microbiology; Crohn Disease - pathology; Crohn's disease; DNA, Bacterial - genetics; Faecalibacterium prausnitzii; fecal microbiota; Feces; Feces - chemistry; Feces - microbiology; Female; Firmicutes; Gram-Positive Bacterial Infections - microbiology; Gram-Positive Bacterial Infections - pathology; Humans; IBD; Inflammatory bowel disease; Male; Microbiota; Organic chemistry; quantitative PCR; Remission (Medicine); Remission Induction; Ruminococcus - genetics; Ruminococcus - isolation & purification; ulcerative colitis; fecal microbiota; IBD; Crohn's disease; ulcerative colitis; colitis; quantitative PCR

The intestinal microbiota is suspected to play a role in colitis and particularly in inflammatory bowel disease (IBD) pathogenesis. The aim was to compare the fecal microbiota composition of patients with colitis to that of healthy subjects (HS).Methodsfecal samples from 22 active Crohn's disea...