SARS-CoV-2 receptor ACE2-dependent implications on the cardiovascular system: From basic science to clinical implications

• Published in: Journal of molecular and cellular cardiology Vol. 144; pp. 47 - 53
• Main Authors: Groß, Sonja, Jahn, Christopher, Cushman, Sarah, Bär, Christian, Thum, Thomas
• Format: Journal Article
• Language: English
• Published: England Elsevier Ltd 01.07.2020; The Authors. Published by Elsevier Ltd
• Subjects: ACE2; Angiotensin-Converting Enzyme 2; Antiviral Agents - pharmacology; Betacoronavirus - pathogenicity; Cardiovascular disease; Cardiovascular Diseases - complications; Cardiovascular Diseases - physiopathology; Coronavirus Infections - drug therapy; Coronavirus Infections - etiology; COVID-19; Host-Pathogen Interactions; Humans; Molecular Targeted Therapy; Pandemics; Peptidyl-Dipeptidase A - metabolism; Pneumonia, Viral - drug therapy; Pneumonia, Viral - etiology; Renin-Angiotensin System - physiology; Risk Factors; SARS-CoV-2; COVID-19; ACE2; Cardiovascular disease; SARS-CoV-2

The current COVID-19 pandemic started several months ago and is still exponentially growing in most parts of the world – this is the most recent and alarming update. COVID-19 requires the collaboration of nearly 200 countries to curb the spread of SARS-CoV-2 while gaining time to explore and improve...