The role of macrophages in anti-inflammatory activity of antidepressant drugs
[Display omitted] Depression is a common disease influencing patients’ quality of life, whose etiology involves complex interactions of environmental, genetic and immunological factors. The latter factors include proinflammatory activation of monocytes and macrophages and increased serum levels of p...
Saved in:
| Published in | Immunobiology (1979) Vol. 222; no. 6; pp. 823 - 830 |
|---|---|
| Main Authors | , , , , , |
| Format | Journal Article |
| Language | English |
| Published |
Netherlands
Elsevier GmbH
01.06.2017
|
| Subjects | |
| Online Access | Get full text |
| ISSN | 0171-2985 1878-3279 |
| DOI | 10.1016/j.imbio.2016.07.001 |
Cover
Loading…
| Abstract | [Display omitted]
Depression is a common disease influencing patients’ quality of life, whose etiology involves complex interactions of environmental, genetic and immunological factors. The latter factors include proinflammatory activation of monocytes and macrophages and increased serum levels of proinflammatory cytokines, altogether formulated as the “macrophage theory of depression”. Our current review summarizes the impact of the most commonly used antidepressant drugs on the immune response with special emphasis on the role of macrophages in the clinically observed effects. The anti-inflammatory action of antidepressants mainly results from their direct interaction with immune cells and from changes in the concentration and the relations of neurotransmitters sensed by these cells. The summarized data revealed that Mφs are one of the leading cell populations involved in drug-mediated immune effects that can be observed both in subjects with depression as well as in individuals not suffering from depression. Thus, currently reviewed immunomodulatory effects of the experimental use of different antidepressant drugs suggest the possibility of utilizing them in complex therapeutic strategies dedicated to various inflammatory and immune-mediated diseases. It is worth noting that an excessive inflammatory reaction is also associated with the pathogenesis of various cardiovascular, metabolic and neuro-endocrine diseases. Thus, the inclusion of antidepressants in the complex therapy of these disorders may have beneficial effects through the enhancement of the mood of the patient and alleviation of chronic inflammation. On the other hand, presented data suggest that the influence of chronically used antidepressants on anti-microbial and anti-tumor immunity could also be taken into consideration. |
|---|---|
| AbstractList | [Display omitted]
Depression is a common disease influencing patients’ quality of life, whose etiology involves complex interactions of environmental, genetic and immunological factors. The latter factors include proinflammatory activation of monocytes and macrophages and increased serum levels of proinflammatory cytokines, altogether formulated as the “macrophage theory of depression”. Our current review summarizes the impact of the most commonly used antidepressant drugs on the immune response with special emphasis on the role of macrophages in the clinically observed effects. The anti-inflammatory action of antidepressants mainly results from their direct interaction with immune cells and from changes in the concentration and the relations of neurotransmitters sensed by these cells. The summarized data revealed that Mφs are one of the leading cell populations involved in drug-mediated immune effects that can be observed both in subjects with depression as well as in individuals not suffering from depression. Thus, currently reviewed immunomodulatory effects of the experimental use of different antidepressant drugs suggest the possibility of utilizing them in complex therapeutic strategies dedicated to various inflammatory and immune-mediated diseases. It is worth noting that an excessive inflammatory reaction is also associated with the pathogenesis of various cardiovascular, metabolic and neuro-endocrine diseases. Thus, the inclusion of antidepressants in the complex therapy of these disorders may have beneficial effects through the enhancement of the mood of the patient and alleviation of chronic inflammation. On the other hand, presented data suggest that the influence of chronically used antidepressants on anti-microbial and anti-tumor immunity could also be taken into consideration. Depression is a common disease influencing patients' quality of life, whose etiology involves complex interactions of environmental, genetic and immunological factors. The latter factors include proinflammatory activation of monocytes and macrophages and increased serum levels of proinflammatory cytokines, altogether formulated as the "macrophage theory of depression". Our current review summarizes the impact of the most commonly used antidepressant drugs on the immune response with special emphasis on the role of macrophages in the clinically observed effects. The anti-inflammatory action of antidepressants mainly results from their direct interaction with immune cells and from changes in the concentration and the relations of neurotransmitters sensed by these cells. The summarized data revealed that Mφs are one of the leading cell populations involved in drug-mediated immune effects that can be observed both in subjects with depression as well as in individuals not suffering from depression. Thus, currently reviewed immunomodulatory effects of the experimental use of different antidepressant drugs suggest the possibility of utilizing them in complex therapeutic strategies dedicated to various inflammatory and immune-mediated diseases. It is worth noting that an excessive inflammatory reaction is also associated with the pathogenesis of various cardiovascular, metabolic and neuro-endocrine diseases. Thus, the inclusion of antidepressants in the complex therapy of these disorders may have beneficial effects through the enhancement of the mood of the patient and alleviation of chronic inflammation. On the other hand, presented data suggest that the influence of chronically used antidepressants on anti-microbial and anti-tumor immunity could also be taken into consideration. Graphical abstract |
| Author | Kozlowski, Michael Filipczak-Bryniarska, Iwona Nazimek, Katarzyna Strobel, Spencer Bryniarski, Krzysztof Bryniarski, Paweł |
| Author_xml | – sequence: 1 givenname: Katarzyna surname: Nazimek fullname: Nazimek, Katarzyna email: katarzyna.nazimek@uj.edu.pl organization: Department of Immunology, Jagiellonian University Medical College, 18 Czysta St, PL 31-121 Krakow, Poland – sequence: 2 givenname: Spencer surname: Strobel fullname: Strobel, Spencer email: spencer.d.strobel@gmail.com organization: Students’ Scientific Society, Department of Immunology, Jagiellonian University Medical College, 18 Czysta St, PL 31-121 Krakow, Poland – sequence: 3 givenname: Paweł surname: Bryniarski fullname: Bryniarski, Paweł email: pablo.bryniarski@uj.edu.pl organization: Students’ Scientific Society, Department of Immunology, Jagiellonian University Medical College, 18 Czysta St, PL 31-121 Krakow, Poland – sequence: 4 givenname: Michael surname: Kozlowski fullname: Kozlowski, Michael email: mj.kozlowski@yahoo.com organization: Department of Immunology, Jagiellonian University Medical College, 18 Czysta St, PL 31-121 Krakow, Poland – sequence: 5 givenname: Iwona surname: Filipczak-Bryniarska fullname: Filipczak-Bryniarska, Iwona email: i.filipczak-bryniarska@uj.edu.pl organization: Department of Pain Treatment and Palliative Care, Jagiellonian University Medical College, 10 Sniadeckich St, PL 31-531 Krakow, Poland – sequence: 6 givenname: Krzysztof surname: Bryniarski fullname: Bryniarski, Krzysztof email: mmbrynia@cyf-kr.edu.pl organization: Department of Immunology, Jagiellonian University Medical College, 18 Czysta St, PL 31-121 Krakow, Poland |
| BackLink | https://www.ncbi.nlm.nih.gov/pubmed/27453459$$D View this record in MEDLINE/PubMed |
| BookMark | eNqFkV9rFDEUxYNU7Lb6CQSZLzBj_kwmCaIgRatQ8cH6HDKZmzbrTLIk2cJ--2a69qWgfUpCzu9czrln6CTEAAi9JbgjmAzvt51fRh87Wh8dFh3G5AXaEClky6hQJ2iDiSAtVZKforOct1WgqJCv0CkVPWc9Vxv04_oWmhRnaKJrFmNT3N2aG8iND40Jxbc-uNksiykxHRpji7_z5bCK198JdglyrtdmSvub_Bq9dGbO8ObveY5-f_1yffGtvfp5-f3i81VrOSGltcAclbznBjvoHRmcIYaLAXouh0EqpZiQE7VcgTITGyUQMYzjqKyTQ296do7eHX13-3GBSe-SX0w66MdcVaCOghoo5wROW19M8TGUZPysCdZrh3qrHzrUa4caC10rqix7wj7a_5_6eKSg5r7zkHS2HoKFySewRU_RP8N_esLb2QdvzfwHDpC3cZ9CrVQTnanG-te623W1ZGCYUcyrwYd_Gzw7_h7NBLVo |
| CitedBy_id | crossref_primary_10_1124_pharmrev_122_000618 crossref_primary_10_1080_15622975_2017_1355473 crossref_primary_10_1007_s00213_016_4408_5 crossref_primary_10_1186_s12974_025_03403_9 crossref_primary_10_1002_advs_202105672 crossref_primary_10_1186_s12888_024_05782_4 crossref_primary_10_1016_j_brainres_2019_146398 crossref_primary_10_3390_ijms23010074 crossref_primary_10_1016_j_cyto_2025_156909 crossref_primary_10_3390_molecules23071611 crossref_primary_10_1016_j_jad_2020_03_022 crossref_primary_10_1186_s12888_017_1411_2 crossref_primary_10_1523_JNEUROSCI_0984_22_2022 crossref_primary_10_3390_ijms23031772 crossref_primary_10_1016_j_neuint_2019_02_003 crossref_primary_10_1186_s12906_019_2497_5 crossref_primary_10_2174_0929867326666190328151539 crossref_primary_10_1007_s11033_022_08219_x crossref_primary_10_1016_j_brs_2017_10_013 crossref_primary_10_1016_j_psychres_2021_114216 crossref_primary_10_1007_s12325_019_01053_x crossref_primary_10_1055_a_1203_5172 crossref_primary_10_3390_ijms20040949 crossref_primary_10_1016_j_bbi_2021_02_009 crossref_primary_10_1016_j_jre_2018_09_001 crossref_primary_10_1177_02698811211069110 crossref_primary_10_3390_microorganisms9122583 crossref_primary_10_1016_j_jad_2021_05_083 crossref_primary_10_7759_cureus_46143 crossref_primary_10_1038_s41598_017_15348_y crossref_primary_10_3390_ijms23169247 crossref_primary_10_1016_j_intimp_2024_113918 crossref_primary_10_1016_j_pharep_2019_04_016 crossref_primary_10_3390_ijms222111374 crossref_primary_10_1371_journal_pone_0276619 crossref_primary_10_1016_j_dci_2023_104666 crossref_primary_10_4049_jimmunol_1901531 crossref_primary_10_1038_s41598_021_89040_7 crossref_primary_10_1016_j_yexmp_2018_08_002 crossref_primary_10_1038_s41398_023_02383_9 crossref_primary_10_1016_j_biocel_2022_106186 crossref_primary_10_1007_s10620_022_07679_2 crossref_primary_10_3389_fphar_2021_652688 crossref_primary_10_1016_j_jpsychires_2021_12_051 crossref_primary_10_1080_15622975_2019_1618494 crossref_primary_10_3390_ijms23073812 crossref_primary_10_3389_fimmu_2020_01869 crossref_primary_10_1097_FBP_0000000000000585 crossref_primary_10_1097_TA_0000000000003646 crossref_primary_10_3389_fcvm_2017_00048 crossref_primary_10_3389_fnins_2022_852506 crossref_primary_10_1038_s41380_021_01149_3 crossref_primary_10_7759_cureus_34158 crossref_primary_10_2174_1570159X16666180426151746 crossref_primary_10_1016_j_nbd_2019_104578 crossref_primary_10_1016_j_exppara_2018_08_004 crossref_primary_10_3389_fneur_2021_721126 crossref_primary_10_1139_cjpp_2020_0307 crossref_primary_10_1002_hup_2855 |
| Cites_doi | 10.1016/j.intimp.2003.11.006 10.1177/1535370216643769 10.1016/j.cellsig.2015.03.013 10.1016/j.cellsig.2015.05.008 10.2174/157339510791823835 10.1002/hup.1103 10.1016/S1470-2045(04)01597-9 10.1016/S1734-1140(13)71481-6 10.1007/978-3-319-07320-0_9 10.1016/S0889-1591(02)00008-9 10.1016/S0024-3205(02)02207-5 10.1016/0192-0561(88)90122-1 10.1016/j.bbi.2011.12.011 10.1038/npp.2011.205 10.1016/j.expneurol.2007.03.022 10.1371/journal.ppat.1003946 10.1902/jop.2011.110370 10.1016/S1734-1140(12)70916-7 10.1016/j.jpsychires.2010.03.005 10.1016/S1734-1140(13)71529-9 10.1016/S1734-1140(12)70866-6 10.1016/S0165-0327(99)00076-2 10.1186/1752-1947-5-112 10.1186/s12872-015-0074-5 10.1017/S1461145714000819 10.1016/j.biopsych.2008.11.029 10.1016/j.bbi.2015.01.015 10.1016/j.ejphar.2014.11.022 10.1189/jlb.0212100 10.1002/hup.191 10.1016/S0165-5728(85)80008-4 10.1159/000107283 10.1007/s00586-015-4239-9 10.1111/j.1600-0773.1999.tb00895.x 10.1016/j.ijcard.2008.02.013 10.1016/S1734-1140(13)71528-7 10.1111/imm.12466 10.1016/j.bbi.2008.06.010 10.1176/ajp.151.4.516 10.1186/1756-0500-4-24 10.1016/j.psyneuen.2011.07.002 10.1017/S1461145708009425 10.1097/YCO.0b013e328315a561 10.1001/2013.jamapsychiatry.4 10.1371/journal.pone.0088316 10.1016/j.intimp.2006.03.015 10.1002/art.27304 10.1111/apha.12430 10.1359/JBMR.040606 10.1097/MCG.0000000000000049 10.1038/npp.2011.132 10.1016/j.intimp.2015.08.001 10.1186/1465-9921-8-35 10.1007/s12031-013-0174-6 10.1038/mp.2008.59 10.1016/j.intimp.2014.02.030 10.1016/j.pnpbp.2007.09.015 10.1097/YCO.0b013e32834b9db6 10.1038/sj.bjp.0705188 10.1371/journal.pone.0120559 10.1002/1529-0131(199912)42:12<2561::AID-ANR8>3.0.CO;2-U 10.1007/s00702-014-1328-6 10.1038/ki.2008.578 10.1016/0162-3109(94)90019-1 10.1002/ijc.25477 10.1016/j.neuroscience.2015.02.028 10.1097/00004714-200104000-00012 10.1016/S1734-1140(12)70934-9 10.1371/journal.pone.0075426 10.1016/j.intimp.2012.06.015 10.1016/S0014-2999(96)00984-3 10.1016/0306-9877(91)90272-Z 10.1111/acps.12576 10.1016/j.pharmthera.2011.01.014 10.1152/ajpgi.00267.2010 10.1016/0192-0561(95)00054-6 10.1016/j.ijcard.2008.10.010 10.1016/S0192-0561(99)00042-9 10.4049/jimmunol.1400710 10.1177/0091270010394852 10.1016/j.intimp.2015.02.029 10.2340/00015555-0288 10.1038/nn.2923 10.1192/bjp.bp.105.011015 10.1016/0162-3109(96)00111-7 10.1055/s-0042-103159 10.1074/jbc.M113.482299 10.1016/j.jneuroim.2004.10.013 10.1016/j.pharmthera.2010.12.002 10.1016/S0006-3223(96)00176-X 10.1016/S0278-5846(01)00155-5 10.1093/icvts/ivv175 10.1146/annurev-publhealth-031912-114409 10.5604/17322693.1004080 10.1023/A:1020819823917 10.1017/S1461145705005663 10.1016/S0893-133X(99)00134-7 10.1159/000339109 |
| ContentType | Journal Article |
| Copyright | 2016 Elsevier GmbH Elsevier GmbH Copyright © 2016 Elsevier GmbH. All rights reserved. |
| Copyright_xml | – notice: 2016 Elsevier GmbH – notice: Elsevier GmbH – notice: Copyright © 2016 Elsevier GmbH. All rights reserved. |
| DBID | AAYXX CITATION CGR CUY CVF ECM EIF NPM |
| DOI | 10.1016/j.imbio.2016.07.001 |
| DatabaseName | CrossRef Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed |
| DatabaseTitle | CrossRef MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) |
| DatabaseTitleList | MEDLINE |
| Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
| DeliveryMethod | fulltext_linktorsrc |
| Discipline | Biology |
| EISSN | 1878-3279 |
| EndPage | 830 |
| ExternalDocumentID | 27453459 10_1016_j_imbio_2016_07_001 S0171298516303205 1_s2_0_S0171298516303205 |
| Genre | Journal Article Review |
| GroupedDBID | --- --K --M -~X .1- .55 .FO .GJ .~1 0R~ 1B1 1P~ 1RT 1~. 1~5 29I 3O- 4.4 457 4G. 53G 5GY 5RE 5VS 7-5 71M 7X7 88E 88I 8AF 8AO 8FE 8FH 8FI 8FJ 8P~ 8R4 8R5 9JM AAAJQ AABNK AAEDT AAEDW AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AARKO AATTM AAXKI AAXUO AAYWO ABBQC ABFNM ABFRF ABGSF ABJNI ABMAC ABMZM ABOHT ABUDA ABUWG ABWVN ABXDB ACDAQ ACGFO ACGFS ACGOD ACIEU ACPRK ACRLP ACRPL ACVFH ADBBV ADCNI ADEZE ADKUU ADMUD ADNMO ADUVX ADVLN AEBSH AEFWE AEHWI AEIPS AEKER AENEX AEUPX AEVXI AFJKZ AFKRA AFPUW AFRHN AFTJW AFXIZ AGCQF AGEKW AGHFR AGQPQ AGRDE AGUBO AGYEJ AHHHB AHMBA AI. AIEXJ AIGII AIIUN AIKHN AITUG AJRQY AJUYK AKBMS AKRWK AKYEP ALMA_UNASSIGNED_HOLDINGS AMRAJ ANKPU ANZVX APXCP ASPBG AVWKF AXJTR AZFZN AZQEC BBNVY BENPR BES BHPHI BKOJK BLXMC BNPGV BPHCQ BVXVI CAG CCPQU CJTIS COF CS3 DU5 DWQXO EBS EFJIC EFKBS EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN FYUFA G-Q GBLVA GNUQQ GROUPED_DOAJ HCIFZ HMCUK HVGLF HZ~ IHE J1W KOM LK8 LUGTX M1P M2P M2Q M41 M7P MO0 M~E N9A O-L O9- O9~ OAUVE OZT P-8 P-9 P2P PC. PHGZM PHGZT PJZUB PPXIY PQGLB PQQKQ PROAC PSQYO PUEGO Q2X Q38 R2- ROL RPZ S0X SDF SDG SES SEW SPCBC SSH SSI SSU SSZ T5F T5J T5K UKHRP UNMZH VH1 X7M Y6R Z5R ZGI ZXP ~G- 3V. AACTN AFCTW AFKWA AJOXV ALIPV AMFUW RIG 0SF AAIAV ABLVK ABYKQ AHPSJ AJBFU DOVZS EFLBG LCYCR AAYXX AGRNS CITATION CGR CUY CVF ECM EIF NPM |
| ID | FETCH-LOGICAL-c511t-ce3f28545a0fe4f16fa1a576e458668999378d2c59e9ad3b8e176bbb9cf864a43 |
| IEDL.DBID | .~1 |
| ISSN | 0171-2985 |
| IngestDate | Mon Jul 21 06:05:56 EDT 2025 Thu Apr 24 23:12:52 EDT 2025 Thu Jul 17 06:02:59 EDT 2025 Fri Feb 23 02:14:25 EST 2024 Sun Feb 23 10:19:14 EST 2025 Tue Aug 26 18:10:40 EDT 2025 |
| IsDoiOpenAccess | false |
| IsOpenAccess | true |
| IsPeerReviewed | true |
| IsScholarly | true |
| Issue | 6 |
| Keywords | SSRI TCA MAO-A SNRI Immune suppression Selective serotonin re-uptake inhibitors Immune regulation Mφs Tricyclic antidepressant drugs Macrophages Serotonin-norepinephrine re-uptake inhibitors Antidepressant drugs serotonin-norepinephrine re-uptake inhibitors selective serotonin re-uptake inhibitors macrophages tricyclic antidepressant drugs monoamine oxidase-A |
| Language | English |
| License | Copyright © 2016 Elsevier GmbH. All rights reserved. |
| LinkModel | DirectLink |
| MergedId | FETCHMERGED-LOGICAL-c511t-ce3f28545a0fe4f16fa1a576e458668999378d2c59e9ad3b8e176bbb9cf864a43 |
| OpenAccessLink | https://ruj.uj.edu.pl/xmlui/handle/item/128345 |
| PMID | 27453459 |
| PageCount | 8 |
| ParticipantIDs | pubmed_primary_27453459 crossref_citationtrail_10_1016_j_imbio_2016_07_001 crossref_primary_10_1016_j_imbio_2016_07_001 elsevier_sciencedirect_doi_10_1016_j_imbio_2016_07_001 elsevier_clinicalkeyesjournals_1_s2_0_S0171298516303205 elsevier_clinicalkey_doi_10_1016_j_imbio_2016_07_001 |
| PublicationCentury | 2000 |
| PublicationDate | 2017-06-01 |
| PublicationDateYYYYMMDD | 2017-06-01 |
| PublicationDate_xml | – month: 06 year: 2017 text: 2017-06-01 day: 01 |
| PublicationDecade | 2010 |
| PublicationPlace | Netherlands |
| PublicationPlace_xml | – name: Netherlands |
| PublicationTitle | Immunobiology (1979) |
| PublicationTitleAlternate | Immunobiology |
| PublicationYear | 2017 |
| Publisher | Elsevier GmbH |
| Publisher_xml | – name: Elsevier GmbH |
| References | Lee, Kim (bib0290) 2006; 6 Curzytek, Kubera, Szczepanik, Basta-Kaim, Leskiewicz, Budziszewska, Lason, Maes (bib0065) 2013; 65 Castanon, Leonard, Neveu, Yirmiya (bib0050) 2002; 16 Miller, Maletic, Raison (bib0325) 2009; 65 Raedler (bib0390) 2011; 24 Yaron, Shirazi, Judovich, Levartovsky, Caspi, Yaron (bib0515) 1999; 42 Campelo, da Silva, Vieira, da Silva, Salgado (bib0040) 2011; 4 Sacre, Medghalchi, Gregory, Brennan, Williams (bib0430) 2010; 62 Smith (bib0445) 1991; 35 Sacerdote, Bianchi, Panerai (bib0425) 1997; 319 Cloonan, Williams (bib0055) 2011; 128 Lin, Song, Kenis, Bosmans, De Jongh, Scharpe, Maes (bib0310) 2000; 58 Baharav, Bar, Taler, Gil-Ad, Karp, Weinberger, Weizman (bib0010) 2012; 19 Ballin, Gershon, Tanay, Brener, Weizman, Meytes (bib0015) 1997; 33 Haenisch, Bönisch (bib0175) 2011; 129 Freire-Garabal, Núñez, Riveiro, Balboa, López, Zamorano, Rodrigo, Rey-Méndez (bib0140) 2002; 72 Stelzhammer, Haenisch, Chan, Cooper, Steiner, Steeb, Martins-de-Souza, Rahmoune, Guest, Bahn (bib0455) 2014; 17 Tynan, Weidenhofer, Hinwood, Cairns, Day, Walker (bib0485) 2012; 26 Beumer, Gibney, Drexhage, Pont-Lezica, Doorduin, Klein, Steiner, Connor, Harkin, Versnel, Drexhage (bib0030) 2012; 92 Branco-de-Almeida, Franco, Castro, dos Santos, Anbinder, Cortelli, Kajiya, Kawai, Rosalen (bib0035) 2012; 83 Nazimek, Kozlowski, Bryniarski, Strobel, Bryk, Myszka, Tyszka, Kuszmiersz, Nowakowski, Filipczak-Bryniarska (bib0355) 2016 Tousoulis, Drolias, Antoniades, Vasiliadou, Marinou, Latsios, Stefanadi, Gounari, Siasos, Papageorgiou, Trikas, Stefanadis (bib0480) 2009; 134 Dharmshaktu, Tayal, Kalra (bib0090) 2012; 52 Filipczak-Bryniarska, Nowak, Sikora, Nazimek, Woron, Wordliczek, Bryniarski (bib0130) 2012; 64 Leonard (bib0305) 2010; 6 Roman, Kusmierczyk, Klimek, Rogoz, Nalepa (bib0410) 2012; 64 Handa, Sekiguchi, Krupkova, Konno (bib0180) 2016; 25 Janssen, Caniato, Verster, Baune (bib0225) 2010; 25 Battaglino, Fu, Späte, Ersoy, Joe, Sedaghat, Stashenko (bib0020) 2004; 19 Kannen, Garcia, Silva, Gasser, Mönch, Alho, Heinsen, Scholz, Friedrich, Heinze, Waaga-Gasser, Stopper (bib0230) 2015; 27 Xia, DePierre, Nassberger (bib0510) 1996; 34 Tanaka, Doe, Horstmann, Ahmad, Ahmad, Min, Reynolds, Suram, Gaydos, Burnham, Vandivier (bib0475) 2014; 289 Leonard (bib0300) 2001; 25 Rabkin, Rabkin, Harrison, Wagner (bib0385) 1994; 151 Gobin, Van Steendam, Denys, Deforce (bib0155) 2014; 20 Herr, Mauler, Witsch, Stallmann, Schmitt, Mezger, Bode, Duerschmied (bib0205) 2014; 9 Achar, Maciel, Collares, Teixeira, Schor (bib0005) 2009; 75 Henderson, Edwards, Weston, Dewdney (bib0200) 1988; 10 Vollmar, Nessler, Kalluri, Hartung, Hemmer (bib0490) 2009; 12 Zhu, Bengtsson, Mix, Thorell, Olsson, Link (bib0525) 1994; 27 Waiskopf, Ofek, Gilboa-Geffen, Bekenstein, Bahat, Bennett, Podoly, Livnah, Hartmann, Soreq (bib0500) 2014; 53 Szuster-Ciesielska, Tustanowska-Stachura, Słotwińska, Marmurowska-Michałowska, Kandefer-Szerszeń (bib0470) 2003; 55 Su, Ma, Yu, Chien, Tsai, Huang, Lin, Chuang, Young, Wang, Tsao (bib0465) 2012; 14 Shajib, Khan (bib0435) 2015; 213 Hannestad, Dellagioia, Bloch (bib0185) 2011; 36 Eyre, Lavretsky, Kartika, Qassim, Baune (bib0125) 2016; 49 Descotes, Tedone, Evreux (bib0085) 1985; 9 Krishnadas, Krishnadas, Cavanagh (bib0250) 2011; 5 Su, Yi, Xu, Zhang (bib0460) 2015; 294 González, Fazzino, Castillo, Mata, Lima (bib0160) 2007; 14 Di Rosso, Palumbo, Genaro (bib0095) 2015 Mukherjee, Mukherjee, Mukhopadhyay, Naskar, Sundar, Dujardin, Roy (bib0335) 2014; 193 Ying, Karlsson, DePierre, Nassberger (bib0520) 2002; 18 Habib, Shaker, El-Gayar, Aboul-Fotouh (bib0165) 2015; 10 Dredge, Connor, Kelly, Leonard (bib0105) 1999; 21 Iskandar, Cassell, Kanuri, Gyawali, Gutierrez, Dassopoulos, Ciorba, Sayuk (bib0220) 2014; 48 Kessler, Bromet (bib0240) 2013; 34 Lekakis, Ikonomidis, Papoutsi, Moutsatsou, Nikolaou, Parissis, Kremastinos (bib0295) 2010; 139 Stanley, Barczak, Silvis, Luo, Sogi, Vokes, Bray, Carpenter, Moore, Siddiqi, Rubin, Hung (bib0450) 2014; 10 Landmann, Schaub, Link, Wacker (bib0280) 1997; 41 Prinz, Priller, Sisodia, Ransohoff (bib0375) 2011; 14 Slota, Shi, Chen, Bevans, Weng (bib0440) 2015; 46 Capuron, Miller (bib0045) 2011; 130 Vuohelainen, Hämäläinen, Paavonen, Karlsson, Moilanen, Mennander (bib0495) 2015; 21 Hashioka, Klegeris, Monji, Kato, Sawada, McGeer, Kanba (bib0195) 2007; 206 Roumestan, Michel, Bichon, Portet, Detoc, Henriquet, Jaffuel, Mathieu (bib0415) 2007; 8 Frick, Rapanelli, Cremaschi, Genaro (bib0145) 2009; 23 O’Brien, Scott, Dinan (bib0365) 2006; 188 Durairaj, Steury, Parameswaran (bib0110) 2015; 25 Freire-Garabal, Núñez, Balboa, López-Delgado, Gallego, García-Caballero, Fernández-Roel, Brenlla, Rey-Méndez (bib0135) 2003; 139 Hickie, Lloyd (bib0210) 1995; 17 Eller, Vasar, Shlik, Maron (bib0115) 2008; 32 El-Nour, Lundeberg, Abdel-Magid, Lonne-Rahm, Azmitia, Nordlind (bib0120) 2007; 87 Haroon, Raison, Miller (bib0190) 2012; 37 Nazimek, Ptak, Nowak, Ptak, Askenase, Bryniarski (bib0360) 2015; 146 Moon, McNeil, Freund (bib0330) 2011; 36 Wong, Dong, Maestre-Mesa, Licinio (bib0505) 2008; 13 Curzytek, Kubera, Majewska-Szczepanik, Szczepanik, Marcinska, Ptak, Duda, Leskiewicz, Basta-Kaim, Budziszewska, Lason, Maes (bib0060) 2013; 65 Kenis, Maes (bib0235) 2002; 5 Kubera, Kenis, Bosmans, Kajta, Basta-Kaim, Scharpe, Budziszewska, Maes (bib0265) 2004; 4 Lanquillon, Krieg, Bening-Abu-Shach, Vedder (bib0285) 2000; 22 Koh, Kim, Kim, Kim, Jung, Song, Kim (bib0245) 2011; 301 Roman, Kreiner, Nalepa (bib0405) 2013; 65 Zychowska, Rojewska, Makuch, Przewlocka, Mika (bib0530) 2015; 749 Belowski, Kowalski, Madej, Herman (bib0025) 2004; 56 de Las Casas-Engel, Corbi (bib0080) 2014; 824 Reiche, Nunes, Morimoto (bib0400) 2004; 5 Kubera, Basta-Kaim, Budziszewska, Rogóz, Skuza, Leskiewicz, Tetich, Jaworska-Feil, Maes, Lason (bib0255) 2006; 9 Rudd, Nicolas, Brown, Fischer-Stenger, Stewart (bib0420) 2005; 159 Nau, Yu, Martin, Nichols (bib0340) 2013; 8 Raison, Rutherford, Woolwine, Shuo, Schettler, Drake, Haroon, Miller (bib0395) 2013; 70 Petersein, Sack, Mergl, Schönherr, Schmidt, Lichtblau, Kirkby, Bauer, Himmerich (bib0370) 2015; 122 Himmerich, Milenović, Fulda, Plümäkers, Sheldrick, Michel, Kircher, Rink (bib0215) 2010; 44 Hadjimitova, Traykov, Goliyski, Ribarov (bib0170) 1999; 84 Nazimek, Filipczak-Bryniarska, Bryniarski (bib0350) 2015; 69 Curzytek, Kubera, Majewska-Szczepanik, Szczepanik, Ptak, Duda, Leśkiewicz, Basta-Kaim, Budziszewska, Regulska, Korzeniak, Głombik, Maes, Lasoń (bib0070) 2015; 28 Dinan (bib0100) 2009; 22 Nazimek, Bryniarski (bib0345) 2012; 66 Mathews, Mathews, Liebenberg (bib0320) 2015; 15 Purdel, Dănciulescu Miulescu, Neamţu, Avramescu, Ilie, Manda, Margină (bib0380) 2015; 56 Kulmatycki, Jamali (bib0275) 2006; 9 Ghosh, Mukherjee, Choudhury, Gupta, Adhikary, Baral, Chattopadhyay (bib0150) 2015; 27 Dahl, Ormstad, Aass, Sandvik, Malt, Andreassen (bib0075) 2016 Maes (bib0315) 2001; 16 Kubera, Lin, Kenis, Bosmans, van Bockstaele, Maes (bib0270) 2001; 21 Kubera, Curzytek, Majewska-Szczepanik, Szczepanik, Marcinska, Ptak, Leskiewicz, Maes, Basta-Kaim, Budziszewska, Detka, Duda, Lason (bib0260) 2012; 64 Nazimek (10.1016/j.imbio.2016.07.001_bib0355) 2016 Vuohelainen (10.1016/j.imbio.2016.07.001_bib0495) 2015; 21 Roumestan (10.1016/j.imbio.2016.07.001_bib0415) 2007; 8 Maes (10.1016/j.imbio.2016.07.001_bib0315) 2001; 16 Leonard (10.1016/j.imbio.2016.07.001_bib0300) 2001; 25 Dinan (10.1016/j.imbio.2016.07.001_bib0100) 2009; 22 Kannen (10.1016/j.imbio.2016.07.001_bib0230) 2015; 27 Haroon (10.1016/j.imbio.2016.07.001_bib0190) 2012; 37 Waiskopf (10.1016/j.imbio.2016.07.001_bib0500) 2014; 53 Roman (10.1016/j.imbio.2016.07.001_bib0410) 2012; 64 Habib (10.1016/j.imbio.2016.07.001_bib0165) 2015; 10 de Las Casas-Engel (10.1016/j.imbio.2016.07.001_bib0080) 2014; 824 Hadjimitova (10.1016/j.imbio.2016.07.001_bib0170) 1999; 84 Krishnadas (10.1016/j.imbio.2016.07.001_bib0250) 2011; 5 Kubera (10.1016/j.imbio.2016.07.001_bib0265) 2004; 4 Slota (10.1016/j.imbio.2016.07.001_bib0440) 2015; 46 Eller (10.1016/j.imbio.2016.07.001_bib0115) 2008; 32 O’Brien (10.1016/j.imbio.2016.07.001_bib0365) 2006; 188 Handa (10.1016/j.imbio.2016.07.001_bib0180) 2016; 25 Kenis (10.1016/j.imbio.2016.07.001_bib0235) 2002; 5 Mathews (10.1016/j.imbio.2016.07.001_bib0320) 2015; 15 Szuster-Ciesielska (10.1016/j.imbio.2016.07.001_bib0470) 2003; 55 Wong (10.1016/j.imbio.2016.07.001_bib0505) 2008; 13 Raedler (10.1016/j.imbio.2016.07.001_bib0390) 2011; 24 Sacre (10.1016/j.imbio.2016.07.001_bib0430) 2010; 62 Tynan (10.1016/j.imbio.2016.07.001_bib0485) 2012; 26 Ghosh (10.1016/j.imbio.2016.07.001_bib0150) 2015; 27 Reiche (10.1016/j.imbio.2016.07.001_bib0400) 2004; 5 Smith (10.1016/j.imbio.2016.07.001_bib0445) 1991; 35 Iskandar (10.1016/j.imbio.2016.07.001_bib0220) 2014; 48 Achar (10.1016/j.imbio.2016.07.001_bib0005) 2009; 75 Petersein (10.1016/j.imbio.2016.07.001_bib0370) 2015; 122 Raison (10.1016/j.imbio.2016.07.001_bib0395) 2013; 70 Henderson (10.1016/j.imbio.2016.07.001_bib0200) 1988; 10 Rabkin (10.1016/j.imbio.2016.07.001_bib0385) 1994; 151 Stelzhammer (10.1016/j.imbio.2016.07.001_bib0455) 2014; 17 Descotes (10.1016/j.imbio.2016.07.001_bib0085) 1985; 9 Baharav (10.1016/j.imbio.2016.07.001_bib0010) 2012; 19 Haenisch (10.1016/j.imbio.2016.07.001_bib0175) 2011; 129 Miller (10.1016/j.imbio.2016.07.001_bib0325) 2009; 65 Filipczak-Bryniarska (10.1016/j.imbio.2016.07.001_bib0130) 2012; 64 Kessler (10.1016/j.imbio.2016.07.001_bib0240) 2013; 34 Moon (10.1016/j.imbio.2016.07.001_bib0330) 2011; 36 Mukherjee (10.1016/j.imbio.2016.07.001_bib0335) 2014; 193 El-Nour (10.1016/j.imbio.2016.07.001_bib0120) 2007; 87 Rudd (10.1016/j.imbio.2016.07.001_bib0420) 2005; 159 Himmerich (10.1016/j.imbio.2016.07.001_bib0215) 2010; 44 Hickie (10.1016/j.imbio.2016.07.001_bib0210) 1995; 17 Gobin (10.1016/j.imbio.2016.07.001_bib0155) 2014; 20 Kubera (10.1016/j.imbio.2016.07.001_bib0260) 2012; 64 Durairaj (10.1016/j.imbio.2016.07.001_bib0110) 2015; 25 Campelo (10.1016/j.imbio.2016.07.001_bib0040) 2011; 4 Dharmshaktu (10.1016/j.imbio.2016.07.001_bib0090) 2012; 52 Eyre (10.1016/j.imbio.2016.07.001_bib0125) 2016; 49 Lanquillon (10.1016/j.imbio.2016.07.001_bib0285) 2000; 22 Belowski (10.1016/j.imbio.2016.07.001_bib0025) 2004; 56 Ballin (10.1016/j.imbio.2016.07.001_bib0015) 1997; 33 Stanley (10.1016/j.imbio.2016.07.001_bib0450) 2014; 10 Nazimek (10.1016/j.imbio.2016.07.001_bib0345) 2012; 66 Herr (10.1016/j.imbio.2016.07.001_bib0205) 2014; 9 Lee (10.1016/j.imbio.2016.07.001_bib0290) 2006; 6 Dahl (10.1016/j.imbio.2016.07.001_bib0075) 2016 Curzytek (10.1016/j.imbio.2016.07.001_bib0065) 2013; 65 Di Rosso (10.1016/j.imbio.2016.07.001_bib0095) 2015 Capuron (10.1016/j.imbio.2016.07.001_bib0045) 2011; 130 Hannestad (10.1016/j.imbio.2016.07.001_bib0185) 2011; 36 Frick (10.1016/j.imbio.2016.07.001_bib0145) 2009; 23 Battaglino (10.1016/j.imbio.2016.07.001_bib0020) 2004; 19 González (10.1016/j.imbio.2016.07.001_bib0160) 2007; 14 Lin (10.1016/j.imbio.2016.07.001_bib0310) 2000; 58 Yaron (10.1016/j.imbio.2016.07.001_bib0515) 1999; 42 Tousoulis (10.1016/j.imbio.2016.07.001_bib0480) 2009; 134 Beumer (10.1016/j.imbio.2016.07.001_bib0030) 2012; 92 Su (10.1016/j.imbio.2016.07.001_bib0460) 2015; 294 Xia (10.1016/j.imbio.2016.07.001_bib0510) 1996; 34 Nau (10.1016/j.imbio.2016.07.001_bib0340) 2013; 8 Zychowska (10.1016/j.imbio.2016.07.001_bib0530) 2015; 749 Freire-Garabal (10.1016/j.imbio.2016.07.001_bib0135) 2003; 139 Landmann (10.1016/j.imbio.2016.07.001_bib0280) 1997; 41 Nazimek (10.1016/j.imbio.2016.07.001_bib0350) 2015; 69 Sacerdote (10.1016/j.imbio.2016.07.001_bib0425) 1997; 319 Kubera (10.1016/j.imbio.2016.07.001_bib0255) 2006; 9 Ying (10.1016/j.imbio.2016.07.001_bib0520) 2002; 18 Shajib (10.1016/j.imbio.2016.07.001_bib0435) 2015; 213 Zhu (10.1016/j.imbio.2016.07.001_bib0525) 1994; 27 Branco-de-Almeida (10.1016/j.imbio.2016.07.001_bib0035) 2012; 83 Curzytek (10.1016/j.imbio.2016.07.001_bib0060) 2013; 65 Prinz (10.1016/j.imbio.2016.07.001_bib0375) 2011; 14 Cloonan (10.1016/j.imbio.2016.07.001_bib0055) 2011; 128 Tanaka (10.1016/j.imbio.2016.07.001_bib0475) 2014; 289 Kubera (10.1016/j.imbio.2016.07.001_bib0270) 2001; 21 Nazimek (10.1016/j.imbio.2016.07.001_bib0360) 2015; 146 Su (10.1016/j.imbio.2016.07.001_bib0465) 2012; 14 Roman (10.1016/j.imbio.2016.07.001_bib0405) 2013; 65 Lekakis (10.1016/j.imbio.2016.07.001_bib0295) 2010; 139 Curzytek (10.1016/j.imbio.2016.07.001_bib0070) 2015; 28 Koh (10.1016/j.imbio.2016.07.001_bib0245) 2011; 301 Freire-Garabal (10.1016/j.imbio.2016.07.001_bib0140) 2002; 72 Kulmatycki (10.1016/j.imbio.2016.07.001_bib0275) 2006; 9 Leonard (10.1016/j.imbio.2016.07.001_bib0305) 2010; 6 Hashioka (10.1016/j.imbio.2016.07.001_bib0195) 2007; 206 Purdel (10.1016/j.imbio.2016.07.001_bib0380) 2015; 56 Castanon (10.1016/j.imbio.2016.07.001_bib0050) 2002; 16 Vollmar (10.1016/j.imbio.2016.07.001_bib0490) 2009; 12 Janssen (10.1016/j.imbio.2016.07.001_bib0225) 2010; 25 Dredge (10.1016/j.imbio.2016.07.001_bib0105) 1999; 21 |
| References_xml | – volume: 27 start-page: 1398 year: 2015 end-page: 1412 ident: bib0150 article-title: Reactive oxygen species in the tumor niche triggers altered activation of macrophages and immunosuppression: role of fluoxetine publication-title: Cell Signal. – volume: 128 start-page: 1712 year: 2011 end-page: 1723 ident: bib0055 article-title: The antidepressants maprotiline and fluoxetine induce type II autophagic cell death in drug-resistant Burkitt’s lymphoma publication-title: Int. J. Cancer – volume: 5 start-page: 401 year: 2002 end-page: 412 ident: bib0235 article-title: Effects of antidepressants on production of cytokines publication-title: Int. J. Neuropharmacol. – volume: 49 start-page: 85 year: 2016 end-page: 96 ident: bib0125 article-title: Modulatory effects of antidepressant classes on the innate and adaptive immune system in depression publication-title: Pharmacopsychiatry – volume: 25 start-page: 201 year: 2010 end-page: 215 ident: bib0225 article-title: A psychoneuroimmunological review on cytokines involved in antidepressant treatment response publication-title: Hum. Psychopharmacol. – volume: 64 start-page: 1368 year: 2012 end-page: 1380 ident: bib0410 article-title: Effects of co-administration of fluoxetine and risperidone on properties of peritoneal and pleural macrophages in rats subjected to the forced swimming test publication-title: Pharmacol. Rep. – volume: 15 start-page: 82 year: 2015 ident: bib0320 article-title: The mechanisms by which antidepressants may reduce coronary heart disease risk publication-title: BMC Cardiovasc. Disord. – volume: 159 start-page: 113 year: 2005 end-page: 118 ident: bib0420 article-title: Peritoneal macrophages express the serotonin transporter publication-title: J. Neuroimmunol. – volume: 749 start-page: 115 year: 2015 end-page: 123 ident: bib0530 article-title: The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain publication-title: Eur. J. Pharmacol. – volume: 34 start-page: 27 year: 1996 end-page: 37 ident: bib0510 article-title: Tricyclic antidepressants inhibit IL-6, IL-1 beta and TNF-alpha release in human blood monocytes and IL-2 and interferon-gamma in T cells publication-title: Immunopharmacology – volume: 146 start-page: 23 year: 2015 end-page: 32 ident: bib0360 article-title: Macrophages play an essential role in antigen-specific immune suppression mediated by T CD8 publication-title: Immunology – volume: 188 start-page: 449 year: 2006 end-page: 452 ident: bib0365 article-title: Antidepressant therapy and C-reactive protein levels publication-title: Br. J. Psychiatry – volume: 134 start-page: 238 year: 2009 end-page: 243 ident: bib0480 article-title: Antidepressive treatment as a modulator of inflammatory process in patients with heart failure: effects on proinflammatory cytokines and acute phase protein levels publication-title: Int. J. Cardiol. – volume: 10 start-page: e0120559 year: 2015 ident: bib0165 article-title: The effects of antidepressants fluoxetine and imipramine on vascular abnormalities and toll like receptor-4 expression in diabetic and non-diabetic rats exposed to chronic stress publication-title: PLoS One – volume: 14 start-page: 1227 year: 2011 end-page: 1235 ident: bib0375 article-title: Heterogeneity of CNS myeloid cells and their roles in neurodegeneration publication-title: Nat. Neurosci. – volume: 62 start-page: 683 year: 2010 end-page: 693 ident: bib0430 article-title: Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors publication-title: Arthr. Rheum. – volume: 9 start-page: 292 year: 2006 end-page: 306 ident: bib0275 article-title: Drug disease interactions: role of inflammatory mediators in depression and variability in antidepressant drug response publication-title: J. Pharm. Pharm. Sci. – volume: 289 start-page: 10466 year: 2014 end-page: 10475 ident: bib0475 article-title: Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells publication-title: J. Biol. Chem. – volume: 53 start-page: 306 year: 2014 end-page: 315 ident: bib0500 article-title: AChE and RACK1 promote the anti-inflammatory properties of fluoxetine publication-title: J. Mol. Neurosci. – volume: 56 start-page: 781 year: 2015 end-page: 788 ident: bib0380 article-title: Studies regarding the protective effects exhibited by antidepressants on cell models publication-title: Rom. J. Morphol. Embryol. – volume: 66 start-page: 507 year: 2012 end-page: 520 ident: bib0345 article-title: The biological activity of macrophages in health and disease publication-title: Postepy Hig. Med. Dosw. – volume: 8 start-page: e75426 year: 2013 ident: bib0340 article-title: Serotonin 5-HT publication-title: PLoS One – volume: 64 start-page: 1200 year: 2012 end-page: 1215 ident: bib0130 article-title: The influence of opioids on the humoral and cell-mediated immune responses in mice: the role of macrophages publication-title: Pharmacol. Rep. – volume: 9 start-page: e88316 year: 2014 ident: bib0205 article-title: Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice publication-title: PLoS One – volume: 8 start-page: 35 year: 2007 ident: bib0415 article-title: Anti-inflammatory properties of desipramine and fluoxetine publication-title: Respir. Res. – volume: 824 start-page: 89 year: 2014 end-page: 115 ident: bib0080 article-title: Serotonin modulation of macrophage polarization: inflammation and beyond publication-title: Adv. Exp. Med. Biol. – volume: 139 start-page: 457 year: 2003 end-page: 463 ident: bib0135 article-title: Serotonin upregulates the activity of phagocytosis through 5-HT1A receptors publication-title: Br. J. Pharmacol. – volume: 23 start-page: 36 year: 2009 end-page: 40 ident: bib0145 article-title: Fluoxetine directly counteracts the adverse effects of chronic stress on T cell immunity by compensatory and specific mechanisms publication-title: Brain Behav. Immun. – volume: 14 start-page: 150 year: 2012 end-page: 156 ident: bib0465 article-title: Glycogen synthase kinase-3β regulates anti-inflammatory property of fluoxetine publication-title: Int. Immunopharmacol. – volume: 5 start-page: 112 year: 2011 ident: bib0250 article-title: Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature publication-title: J. Med. Case Rep. – volume: 10 start-page: 361 year: 1988 end-page: 367 ident: bib0200 article-title: Immunological studies on paroxetine, a novel anti-depressant drug publication-title: Int. J. Immunopharmacol. – volume: 28 start-page: 1091 year: 2015 end-page: 1096 ident: bib0070 article-title: Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction is connected with their suppressive effect on NKT and CD8(+) T cells but not on TCR delta T cells publication-title: Int. Immunopharmacol. – volume: 58 start-page: 69 year: 2000 end-page: 74 ident: bib0310 article-title: The in vitro immunosuppressive effects of moclobemide in healthy volunteers publication-title: J. Affect. Disord. – volume: 4 start-page: 185 year: 2004 end-page: 192 ident: bib0265 article-title: Stimulatory effect of antidepressants on the production of IL-6 publication-title: Int. Immunopharmacol. – volume: 56 start-page: 837 year: 2004 end-page: 842 ident: bib0025 article-title: Influence of antidepressant drugs on macrophage cytotoxic activity in rats publication-title: Pol. J. Pharmacol. – volume: 55 start-page: 353 year: 2003 end-page: 362 ident: bib0470 article-title: In vitro immunoregulatory effects of antidepressants in healthy volunteers publication-title: Pol. J. Pharmacol. – volume: 26 start-page: 469 year: 2012 end-page: 479 ident: bib0485 article-title: A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia publication-title: Brain Behav. Immun. – volume: 25 start-page: 485 year: 2015 end-page: 492 ident: bib0110 article-title: Paroxetine differentially modulates LPS-induced TNFa and IL-6 production in mouse macrophages publication-title: Int. Immunopharmacol. – volume: 130 start-page: 226 year: 2011 end-page: 238 ident: bib0045 article-title: Immune system to brain signaling: neuropsychopharmacological implications publication-title: Pharmacol. Ther. – volume: 129 start-page: 352 year: 2011 end-page: 368 ident: bib0175 article-title: Depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters publication-title: Pharmacol. Ther. – volume: 52 start-page: 6 year: 2012 end-page: 17 ident: bib0090 article-title: Efficacy of antidepressants as analgesics: a review publication-title: J. Clin. Pharmacol. – volume: 13 start-page: 800 year: 2008 end-page: 812 ident: bib0505 article-title: Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response publication-title: Mol. Psychiatry – volume: 6 start-page: 205 year: 2010 end-page: 212 ident: bib0305 article-title: The concept of depression as a dysfunction of the immune system publication-title: Curr. Immunol. Rev. – volume: 5 start-page: 617 year: 2004 end-page: 625 ident: bib0400 article-title: Stress, depression, the immune system, and cancer publication-title: Lancet Oncol. – volume: 92 start-page: 959 year: 2012 end-page: 975 ident: bib0030 article-title: The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes publication-title: J. Leukoc. Biol. – volume: 22 start-page: 32 year: 2009 end-page: 36 ident: bib0100 article-title: Inflammatory markers in depression publication-title: Curr. Opin. Psychiatry – volume: 48 start-page: 423 year: 2014 end-page: 429 ident: bib0220 article-title: Tricyclic antidepressants for management of residual symptoms in inflammatory bowel disease publication-title: J. Clin. Gastroenterol. – volume: 24 start-page: 519 year: 2011 end-page: 525 ident: bib0390 article-title: Inflammatory mechanisms in major depressive disorder publication-title: Curr. Opin. Psychiatry – volume: 70 start-page: 31 year: 2013 end-page: 41 ident: bib0395 article-title: A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers publication-title: JAMA Psychiatry – volume: 18 start-page: 425 year: 2002 end-page: 437 ident: bib0520 article-title: Tricyclic antidepressants prevent the differentiation of monocytes into macrophage-like cells in vitro publication-title: Cell. Biol. Toxicol. – volume: 35 start-page: 298 year: 1991 end-page: 306 ident: bib0445 article-title: The macrophage theory of depression publication-title: Med. Hypotheses – year: 2016 ident: bib0355 article-title: Repeatedly administered antidepressant drugs modulate humoral and cellular immune response in mice through action on macrophages publication-title: Exp. Biol. Med. (Maywood) – volume: 17 start-page: 677 year: 1995 end-page: 683 ident: bib0210 article-title: Are cytokines associated with neuropsychiatric syndromes in humans? publication-title: Int. J. Immunopharmacol. – volume: 34 start-page: 119 year: 2013 end-page: 138 ident: bib0240 article-title: The epidemiology of depression across cultures publication-title: Annu. Rev. Public Health – volume: 6 start-page: 1298 year: 2006 end-page: 1304 ident: bib0290 article-title: The role of IL-12 and TGF-beta1 in the pathophysiology of major depressive disorder publication-title: Int. Immunopharmacol. – volume: 193 start-page: 4083 year: 2014 end-page: 4094 ident: bib0335 article-title: Imipramine exploits histone deacetylase 11 to increase the IL-12/IL-10 ratio in macrophages infected with antimony-resistant Leishmania donovani and clears organ parasites in experimental infection publication-title: J. Immunol. – volume: 17 start-page: 1599 year: 2014 end-page: 1608 ident: bib0455 article-title: Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients publication-title: Int. J. Neuropsychopharmacol. – volume: 33 start-page: 720 year: 1997 end-page: 723 ident: bib0015 article-title: The antidepressant fluvoxamine increases natural killer cell counts in cancer patients publication-title: Isr. J. Med. Sci. – volume: 42 start-page: 2561 year: 1999 end-page: 2568 ident: bib0515 article-title: Fluoxetine and amitriptyline inhibit nitric oxide prostaglandin E2, and hyaluronic acid production in human synovial cells and synovial tissue cultures publication-title: Arthr. Rheum. – volume: 75 start-page: 596 year: 2009 end-page: 604 ident: bib0005 article-title: Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis publication-title: Kidney Int. – volume: 21 start-page: 199 year: 2001 end-page: 206 ident: bib0270 article-title: Anti-inflammatory effects of antidepressants through suppression of the interferon-gamma/interleukin-10 production ratio publication-title: J. Clin. Psychopharmacol. – volume: 9 start-page: 81 year: 1985 end-page: 85 ident: bib0085 article-title: Different effects of psychotropic drugs on delayed hypersensitivity responses in mice publication-title: J. Neuroimmunol. – volume: 25 start-page: 877 year: 2016 end-page: 887 ident: bib0180 article-title: The effect of serotonin-noradrenaline reuptake inhibitor duloxetine on the intervertebral disk-related radiculopathy in rats publication-title: Eur. Spine J. – volume: 319 start-page: 287 year: 1997 end-page: 290 ident: bib0425 article-title: In vivo and in vitro clomipramine treatment decreases the migration of macrophages in the rat publication-title: Eur. J. Pharmacol. – volume: 9 start-page: 297 year: 2006 end-page: 305 ident: bib0255 article-title: Effect of amantadine and imipramine on immunological parameters of rats subjected to a forced swimming test publication-title: Int. J. Neuropsychopharmacol. – volume: 25 start-page: 767 year: 2001 end-page: 780 ident: bib0300 article-title: The immune system, depression and the action of antidepressants publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry – volume: 36 start-page: 1431 year: 2011 end-page: 1440 ident: bib0330 article-title: Macrophages make me sick: how macrophage activation states influence sickness behavior publication-title: Psychoneuroendocrinology – volume: 84 start-page: 170 year: 1999 end-page: 173 ident: bib0170 article-title: Effects of some psychotropic drugs on the activated macrophage-induced luminol-dependent chemiluminescence publication-title: Pharmacol. Toxicol. – volume: 122 start-page: 109 year: 2015 end-page: 122 ident: bib0370 article-title: Impact of lithium alone and in combination with antidepressants on cytokine production in vitro publication-title: J. Neural. Transm. (Vienna) – volume: 22 start-page: 370 year: 2000 end-page: 379 ident: bib0285 article-title: Cytokine production and treatment response in major depressive disorder publication-title: Neuropsychopharmacology – volume: 27 start-page: 1781 year: 2015 end-page: 1788 ident: bib0230 article-title: Oncostatic effects of fluoxetine in experimental colon cancer models publication-title: Cell Signal. – volume: 64 start-page: 714 year: 2012 end-page: 722 ident: bib0260 article-title: Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction publication-title: Pharmacol. Rep. – year: 2015 ident: bib0095 article-title: Immunomodulatory effects of fluoxetine: a new potential pharmacological action for a classic antidepressant drug? publication-title: Pharmacol. Res. – volume: 4 start-page: 24 year: 2011 ident: bib0040 article-title: Effects of immunomodulatory drugs on TNF-α and IL-12 production by purified epidermal langerhans cells and peritoneal macrophages publication-title: BMC Res. Notes – volume: 87 start-page: 390 year: 2007 end-page: 396 ident: bib0120 article-title: Serotonergic mechanisms in human allergic contact dermatitis publication-title: Acta Derm. Venereol. – volume: 37 start-page: 137 year: 2012 end-page: 162 ident: bib0190 article-title: Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior publication-title: Neuropsychopharmacology – volume: 36 start-page: 2452 year: 2011 end-page: 2459 ident: bib0185 article-title: The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis publication-title: Neuropsychopharmacology – volume: 65 start-page: 1237 year: 2013 end-page: 1246 ident: bib0060 article-title: Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs publication-title: Pharmacol. Rep. – volume: 65 start-page: 1663 year: 2013 end-page: 1672 ident: bib0405 article-title: Macrophages and depression—a misalliance or well-arranged marriage? publication-title: Pharmacol. Rep. – volume: 10 start-page: e1003946 year: 2014 ident: bib0450 article-title: Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth publication-title: PLoS Pathog. – volume: 69 start-page: 1114 year: 2015 end-page: 1129 ident: bib0350 article-title: The role of medicaments, exosomes and miRNA molecules in modulation of macrophage immune activity publication-title: Postepy Hig. Med. Dosw. – volume: 21 start-page: 663 year: 1999 end-page: 673 ident: bib0105 article-title: Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats publication-title: Int. J. Immunopharmacol. – volume: 14 start-page: 8 year: 2007 end-page: 15 ident: bib0160 article-title: Serotonin, 5-HT1A serotonin receptors and proliferation of lymphocytes in major depression patients publication-title: Neuroimmunomodulation – volume: 83 start-page: 664 year: 2012 end-page: 671 ident: bib0035 article-title: Fluoxetine inhibits inflammatory response and bone loss in a rat model of ligature-induced periodontitis publication-title: J. Periodontol. – volume: 27 start-page: 225 year: 1994 end-page: 244 ident: bib0525 article-title: Effect of monoamine reuptake inhibiting antidepressants on major histocompatibility complex expression on macrophages in normal rats and rats with experimental allergic neuritis (EAN) publication-title: Immunopharmacology – volume: 301 start-page: G9 year: 2011 end-page: 19 ident: bib0245 article-title: Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. – volume: 19 start-page: 309 year: 2012 end-page: 318 ident: bib0010 article-title: Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis publication-title: Neuroimmunomodulation – volume: 41 start-page: 675 year: 1997 end-page: 681 ident: bib0280 article-title: Unaltered monocyte function in patients with major depression before and after three months of antidepressive therapy publication-title: Biol. Psychiatry – volume: 19 start-page: 1420 year: 2004 end-page: 1431 ident: bib0020 article-title: Serotonin regulates osteoclast differentiation through its transporter publication-title: J. Bone Miner. Res. – volume: 65 start-page: 732 year: 2009 end-page: 741 ident: bib0325 article-title: Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression publication-title: Biol. Psychiatry – volume: 20 start-page: 148 year: 2014 end-page: 156 ident: bib0155 article-title: Selective serotonin reuptake inhibitors as a novel class of immunosuppressants publication-title: Int. Immunopharmacol. – volume: 294 start-page: 60 year: 2015 end-page: 68 ident: bib0460 article-title: Fluoxetine and S-citalopram inhibit M1 activation and promote M2 activation of microglia in vitro publication-title: Neuroscience – volume: 139 start-page: 150 year: 2010 end-page: 158 ident: bib0295 article-title: Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules publication-title: Int. J. Cardiol. – volume: 32 start-page: 445 year: 2008 end-page: 450 ident: bib0115 article-title: Pro-inflammatory cytokines and treatment response to escitalopram in major depressive disorder publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry – volume: 206 start-page: 33 year: 2007 end-page: 42 ident: bib0195 article-title: Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide publication-title: Exp. Neurol. – year: 2016 ident: bib0075 article-title: Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels publication-title: Acta Psychiatr. Scand. – volume: 151 start-page: 516 year: 1994 end-page: 523 ident: bib0385 article-title: Effect of imipramine on mood and enumerative measures of immune status in depressed patients with HIV illness publication-title: Am. J. Psychiatry – volume: 65 start-page: 1673 year: 2013 end-page: 1680 ident: bib0065 article-title: Crosstalk between contact hypersensitivity reaction and antidepressant drugs publication-title: Pharmacol. Rep. – volume: 21 start-page: 441 year: 2015 end-page: 449 ident: bib0495 article-title: Inhibition of monoamine oxidase A increases recovery after experimental cardiac arrest publication-title: Interact. Cardiovasc. Thorac. Surg. – volume: 46 start-page: 168 year: 2015 end-page: 179 ident: bib0440 article-title: Norepinephrine preferentially modulates memory CD8T cell function inducing inflammatory cytokine production and reducing proliferation in response to activation publication-title: Brain Behav. Immun. – volume: 16 start-page: 569 year: 2002 end-page: 574 ident: bib0050 article-title: Effects of antidepressants on cytokine production and actions publication-title: Brain Behav. Immun. – volume: 12 start-page: 525 year: 2009 end-page: 536 ident: bib0490 article-title: The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines publication-title: Int. J. Neuropsychopharmacol. – volume: 72 start-page: 173 year: 2002 end-page: 183 ident: bib0140 article-title: Effects of fluoxetine on the activity of phagocytosis in stressed mice publication-title: Life Sci. – volume: 44 start-page: 1052 year: 2010 end-page: 1057 ident: bib0215 article-title: Regulatory T cells increased while IL-1β decreased during antidepressant therapy publication-title: J. Psychiatr. Res. – volume: 16 start-page: 95 year: 2001 end-page: 103 ident: bib0315 article-title: The immunomodulatory effects of antidepressants publication-title: Hum. Psychopharmacol. – volume: 213 start-page: 561 year: 2015 end-page: 574 ident: bib0435 article-title: The role of serotonin and its receptors in activation of immune responses and inflammation publication-title: Acta Physiol. (Oxf.) – volume: 4 start-page: 185 year: 2004 ident: 10.1016/j.imbio.2016.07.001_bib0265 article-title: Stimulatory effect of antidepressants on the production of IL-6 publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2003.11.006 – year: 2016 ident: 10.1016/j.imbio.2016.07.001_bib0355 article-title: Repeatedly administered antidepressant drugs modulate humoral and cellular immune response in mice through action on macrophages publication-title: Exp. Biol. Med. (Maywood) doi: 10.1177/1535370216643769 – year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0095 article-title: Immunomodulatory effects of fluoxetine: a new potential pharmacological action for a classic antidepressant drug? publication-title: Pharmacol. Res. – volume: 27 start-page: 1398 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0150 article-title: Reactive oxygen species in the tumor niche triggers altered activation of macrophages and immunosuppression: role of fluoxetine publication-title: Cell Signal. doi: 10.1016/j.cellsig.2015.03.013 – volume: 27 start-page: 1781 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0230 article-title: Oncostatic effects of fluoxetine in experimental colon cancer models publication-title: Cell Signal. doi: 10.1016/j.cellsig.2015.05.008 – volume: 6 start-page: 205 year: 2010 ident: 10.1016/j.imbio.2016.07.001_bib0305 article-title: The concept of depression as a dysfunction of the immune system publication-title: Curr. Immunol. Rev. doi: 10.2174/157339510791823835 – volume: 25 start-page: 201 year: 2010 ident: 10.1016/j.imbio.2016.07.001_bib0225 article-title: A psychoneuroimmunological review on cytokines involved in antidepressant treatment response publication-title: Hum. Psychopharmacol. doi: 10.1002/hup.1103 – volume: 5 start-page: 617 year: 2004 ident: 10.1016/j.imbio.2016.07.001_bib0400 article-title: Stress, depression, the immune system, and cancer publication-title: Lancet Oncol. doi: 10.1016/S1470-2045(04)01597-9 – volume: 65 start-page: 1237 year: 2013 ident: 10.1016/j.imbio.2016.07.001_bib0060 article-title: Inhibition of 2,4-dinitrofluorobenzene-induced contact hypersensitivity reaction by antidepressant drugs publication-title: Pharmacol. Rep. doi: 10.1016/S1734-1140(13)71481-6 – volume: 824 start-page: 89 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0080 article-title: Serotonin modulation of macrophage polarization: inflammation and beyond publication-title: Adv. Exp. Med. Biol. doi: 10.1007/978-3-319-07320-0_9 – volume: 16 start-page: 569 year: 2002 ident: 10.1016/j.imbio.2016.07.001_bib0050 article-title: Effects of antidepressants on cytokine production and actions publication-title: Brain Behav. Immun. doi: 10.1016/S0889-1591(02)00008-9 – volume: 72 start-page: 173 year: 2002 ident: 10.1016/j.imbio.2016.07.001_bib0140 article-title: Effects of fluoxetine on the activity of phagocytosis in stressed mice publication-title: Life Sci. doi: 10.1016/S0024-3205(02)02207-5 – volume: 10 start-page: 361 year: 1988 ident: 10.1016/j.imbio.2016.07.001_bib0200 article-title: Immunological studies on paroxetine, a novel anti-depressant drug publication-title: Int. J. Immunopharmacol. doi: 10.1016/0192-0561(88)90122-1 – volume: 33 start-page: 720 year: 1997 ident: 10.1016/j.imbio.2016.07.001_bib0015 article-title: The antidepressant fluvoxamine increases natural killer cell counts in cancer patients publication-title: Isr. J. Med. Sci. – volume: 26 start-page: 469 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0485 article-title: A comparative examination of the anti-inflammatory effects of SSRI and SNRI antidepressants on LPS stimulated microglia publication-title: Brain Behav. Immun. doi: 10.1016/j.bbi.2011.12.011 – volume: 37 start-page: 137 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0190 article-title: Psychoneuroimmunology meets neuropsychopharmacology: translational implications of the impact of inflammation on behavior publication-title: Neuropsychopharmacology doi: 10.1038/npp.2011.205 – volume: 206 start-page: 33 year: 2007 ident: 10.1016/j.imbio.2016.07.001_bib0195 article-title: Antidepressants inhibit interferon-gamma-induced microglial production of IL-6 and nitric oxide publication-title: Exp. Neurol. doi: 10.1016/j.expneurol.2007.03.022 – volume: 10 start-page: e1003946 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0450 article-title: Identification of host-targeted small molecules that restrict intracellular Mycobacterium tuberculosis growth publication-title: PLoS Pathog. doi: 10.1371/journal.ppat.1003946 – volume: 83 start-page: 664 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0035 article-title: Fluoxetine inhibits inflammatory response and bone loss in a rat model of ligature-induced periodontitis publication-title: J. Periodontol. doi: 10.1902/jop.2011.110370 – volume: 64 start-page: 1200 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0130 article-title: The influence of opioids on the humoral and cell-mediated immune responses in mice: the role of macrophages publication-title: Pharmacol. Rep. doi: 10.1016/S1734-1140(12)70916-7 – volume: 44 start-page: 1052 year: 2010 ident: 10.1016/j.imbio.2016.07.001_bib0215 article-title: Regulatory T cells increased while IL-1β decreased during antidepressant therapy publication-title: J. Psychiatr. Res. doi: 10.1016/j.jpsychires.2010.03.005 – volume: 65 start-page: 1673 year: 2013 ident: 10.1016/j.imbio.2016.07.001_bib0065 article-title: Crosstalk between contact hypersensitivity reaction and antidepressant drugs publication-title: Pharmacol. Rep. doi: 10.1016/S1734-1140(13)71529-9 – volume: 64 start-page: 714 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0260 article-title: Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction publication-title: Pharmacol. Rep. doi: 10.1016/S1734-1140(12)70866-6 – volume: 58 start-page: 69 year: 2000 ident: 10.1016/j.imbio.2016.07.001_bib0310 article-title: The in vitro immunosuppressive effects of moclobemide in healthy volunteers publication-title: J. Affect. Disord. doi: 10.1016/S0165-0327(99)00076-2 – volume: 55 start-page: 353 year: 2003 ident: 10.1016/j.imbio.2016.07.001_bib0470 article-title: In vitro immunoregulatory effects of antidepressants in healthy volunteers publication-title: Pol. J. Pharmacol. – volume: 5 start-page: 112 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0250 article-title: Sustained remission of rheumatoid arthritis with a specific serotonin reuptake inhibitor antidepressant: a case report and review of the literature publication-title: J. Med. Case Rep. doi: 10.1186/1752-1947-5-112 – volume: 15 start-page: 82 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0320 article-title: The mechanisms by which antidepressants may reduce coronary heart disease risk publication-title: BMC Cardiovasc. Disord. doi: 10.1186/s12872-015-0074-5 – volume: 17 start-page: 1599 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0455 article-title: Proteomic changes in serum of first onset, antidepressant drug-naïve major depression patients publication-title: Int. J. Neuropsychopharmacol. doi: 10.1017/S1461145714000819 – volume: 65 start-page: 732 year: 2009 ident: 10.1016/j.imbio.2016.07.001_bib0325 article-title: Inflammation and its discontents: the role of cytokines in the pathophysiology of major depression publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2008.11.029 – volume: 46 start-page: 168 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0440 article-title: Norepinephrine preferentially modulates memory CD8T cell function inducing inflammatory cytokine production and reducing proliferation in response to activation publication-title: Brain Behav. Immun. doi: 10.1016/j.bbi.2015.01.015 – volume: 749 start-page: 115 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0530 article-title: The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2014.11.022 – volume: 92 start-page: 959 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0030 article-title: The immune theory of psychiatric diseases: a key role for activated microglia and circulating monocytes publication-title: J. Leukoc. Biol. doi: 10.1189/jlb.0212100 – volume: 16 start-page: 95 year: 2001 ident: 10.1016/j.imbio.2016.07.001_bib0315 article-title: The immunomodulatory effects of antidepressants publication-title: Hum. Psychopharmacol. doi: 10.1002/hup.191 – volume: 9 start-page: 81 year: 1985 ident: 10.1016/j.imbio.2016.07.001_bib0085 article-title: Different effects of psychotropic drugs on delayed hypersensitivity responses in mice publication-title: J. Neuroimmunol. doi: 10.1016/S0165-5728(85)80008-4 – volume: 14 start-page: 8 year: 2007 ident: 10.1016/j.imbio.2016.07.001_bib0160 article-title: Serotonin, 5-HT1A serotonin receptors and proliferation of lymphocytes in major depression patients publication-title: Neuroimmunomodulation doi: 10.1159/000107283 – volume: 25 start-page: 877 year: 2016 ident: 10.1016/j.imbio.2016.07.001_bib0180 article-title: The effect of serotonin-noradrenaline reuptake inhibitor duloxetine on the intervertebral disk-related radiculopathy in rats publication-title: Eur. Spine J. doi: 10.1007/s00586-015-4239-9 – volume: 84 start-page: 170 year: 1999 ident: 10.1016/j.imbio.2016.07.001_bib0170 article-title: Effects of some psychotropic drugs on the activated macrophage-induced luminol-dependent chemiluminescence publication-title: Pharmacol. Toxicol. doi: 10.1111/j.1600-0773.1999.tb00895.x – volume: 134 start-page: 238 year: 2009 ident: 10.1016/j.imbio.2016.07.001_bib0480 article-title: Antidepressive treatment as a modulator of inflammatory process in patients with heart failure: effects on proinflammatory cytokines and acute phase protein levels publication-title: Int. J. Cardiol. doi: 10.1016/j.ijcard.2008.02.013 – volume: 65 start-page: 1663 year: 2013 ident: 10.1016/j.imbio.2016.07.001_bib0405 article-title: Macrophages and depression—a misalliance or well-arranged marriage? publication-title: Pharmacol. Rep. doi: 10.1016/S1734-1140(13)71528-7 – volume: 146 start-page: 23 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0360 article-title: Macrophages play an essential role in antigen-specific immune suppression mediated by T CD8+ cell-derived exosomes publication-title: Immunology doi: 10.1111/imm.12466 – volume: 23 start-page: 36 year: 2009 ident: 10.1016/j.imbio.2016.07.001_bib0145 article-title: Fluoxetine directly counteracts the adverse effects of chronic stress on T cell immunity by compensatory and specific mechanisms publication-title: Brain Behav. Immun. doi: 10.1016/j.bbi.2008.06.010 – volume: 151 start-page: 516 year: 1994 ident: 10.1016/j.imbio.2016.07.001_bib0385 article-title: Effect of imipramine on mood and enumerative measures of immune status in depressed patients with HIV illness publication-title: Am. J. Psychiatry doi: 10.1176/ajp.151.4.516 – volume: 4 start-page: 24 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0040 article-title: Effects of immunomodulatory drugs on TNF-α and IL-12 production by purified epidermal langerhans cells and peritoneal macrophages publication-title: BMC Res. Notes doi: 10.1186/1756-0500-4-24 – volume: 36 start-page: 1431 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0330 article-title: Macrophages make me sick: how macrophage activation states influence sickness behavior publication-title: Psychoneuroendocrinology doi: 10.1016/j.psyneuen.2011.07.002 – volume: 12 start-page: 525 year: 2009 ident: 10.1016/j.imbio.2016.07.001_bib0490 article-title: The antidepressant venlafaxine ameliorates murine experimental autoimmune encephalomyelitis by suppression of pro-inflammatory cytokines publication-title: Int. J. Neuropsychopharmacol. doi: 10.1017/S1461145708009425 – volume: 22 start-page: 32 year: 2009 ident: 10.1016/j.imbio.2016.07.001_bib0100 article-title: Inflammatory markers in depression publication-title: Curr. Opin. Psychiatry doi: 10.1097/YCO.0b013e328315a561 – volume: 70 start-page: 31 year: 2013 ident: 10.1016/j.imbio.2016.07.001_bib0395 article-title: A randomized controlled trial of the tumor necrosis factor antagonist infliximab for treatment-resistant depression: the role of baseline inflammatory biomarkers publication-title: JAMA Psychiatry doi: 10.1001/2013.jamapsychiatry.4 – volume: 9 start-page: e88316 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0205 article-title: Acute fluoxetine treatment induces slow rolling of leukocytes on endothelium in mice publication-title: PLoS One doi: 10.1371/journal.pone.0088316 – volume: 6 start-page: 1298 year: 2006 ident: 10.1016/j.imbio.2016.07.001_bib0290 article-title: The role of IL-12 and TGF-beta1 in the pathophysiology of major depressive disorder publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2006.03.015 – volume: 62 start-page: 683 year: 2010 ident: 10.1016/j.imbio.2016.07.001_bib0430 article-title: Fluoxetine and citalopram exhibit potent antiinflammatory activity in human and murine models of rheumatoid arthritis and inhibit toll-like receptors publication-title: Arthr. Rheum. doi: 10.1002/art.27304 – volume: 5 start-page: 401 year: 2002 ident: 10.1016/j.imbio.2016.07.001_bib0235 article-title: Effects of antidepressants on production of cytokines publication-title: Int. J. Neuropharmacol. – volume: 213 start-page: 561 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0435 article-title: The role of serotonin and its receptors in activation of immune responses and inflammation publication-title: Acta Physiol. (Oxf.) doi: 10.1111/apha.12430 – volume: 56 start-page: 837 year: 2004 ident: 10.1016/j.imbio.2016.07.001_bib0025 article-title: Influence of antidepressant drugs on macrophage cytotoxic activity in rats publication-title: Pol. J. Pharmacol. – volume: 56 start-page: 781 issue: 2 Suppl year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0380 article-title: Studies regarding the protective effects exhibited by antidepressants on cell models publication-title: Rom. J. Morphol. Embryol. – volume: 19 start-page: 1420 year: 2004 ident: 10.1016/j.imbio.2016.07.001_bib0020 article-title: Serotonin regulates osteoclast differentiation through its transporter publication-title: J. Bone Miner. Res. doi: 10.1359/JBMR.040606 – volume: 48 start-page: 423 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0220 article-title: Tricyclic antidepressants for management of residual symptoms in inflammatory bowel disease publication-title: J. Clin. Gastroenterol. doi: 10.1097/MCG.0000000000000049 – volume: 36 start-page: 2452 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0185 article-title: The effect of antidepressant medication treatment on serum levels of inflammatory cytokines: a meta-analysis publication-title: Neuropsychopharmacology doi: 10.1038/npp.2011.132 – volume: 28 start-page: 1091 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0070 article-title: Inhibitory effect of antidepressant drugs on contact hypersensitivity reaction is connected with their suppressive effect on NKT and CD8(+) T cells but not on TCR delta T cells publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2015.08.001 – volume: 69 start-page: 1114 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0350 article-title: The role of medicaments, exosomes and miRNA molecules in modulation of macrophage immune activity publication-title: Postepy Hig. Med. Dosw. – volume: 8 start-page: 35 year: 2007 ident: 10.1016/j.imbio.2016.07.001_bib0415 article-title: Anti-inflammatory properties of desipramine and fluoxetine publication-title: Respir. Res. doi: 10.1186/1465-9921-8-35 – volume: 53 start-page: 306 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0500 article-title: AChE and RACK1 promote the anti-inflammatory properties of fluoxetine publication-title: J. Mol. Neurosci. doi: 10.1007/s12031-013-0174-6 – volume: 13 start-page: 800 year: 2008 ident: 10.1016/j.imbio.2016.07.001_bib0505 article-title: Polymorphisms in inflammation-related genes are associated with susceptibility to major depression and antidepressant response publication-title: Mol. Psychiatry doi: 10.1038/mp.2008.59 – volume: 20 start-page: 148 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0155 article-title: Selective serotonin reuptake inhibitors as a novel class of immunosuppressants publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2014.02.030 – volume: 32 start-page: 445 year: 2008 ident: 10.1016/j.imbio.2016.07.001_bib0115 article-title: Pro-inflammatory cytokines and treatment response to escitalopram in major depressive disorder publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry doi: 10.1016/j.pnpbp.2007.09.015 – volume: 9 start-page: 292 year: 2006 ident: 10.1016/j.imbio.2016.07.001_bib0275 article-title: Drug disease interactions: role of inflammatory mediators in depression and variability in antidepressant drug response publication-title: J. Pharm. Pharm. Sci. – volume: 24 start-page: 519 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0390 article-title: Inflammatory mechanisms in major depressive disorder publication-title: Curr. Opin. Psychiatry doi: 10.1097/YCO.0b013e32834b9db6 – volume: 139 start-page: 457 year: 2003 ident: 10.1016/j.imbio.2016.07.001_bib0135 article-title: Serotonin upregulates the activity of phagocytosis through 5-HT1A receptors publication-title: Br. J. Pharmacol. doi: 10.1038/sj.bjp.0705188 – volume: 10 start-page: e0120559 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0165 article-title: The effects of antidepressants fluoxetine and imipramine on vascular abnormalities and toll like receptor-4 expression in diabetic and non-diabetic rats exposed to chronic stress publication-title: PLoS One doi: 10.1371/journal.pone.0120559 – volume: 42 start-page: 2561 year: 1999 ident: 10.1016/j.imbio.2016.07.001_bib0515 article-title: Fluoxetine and amitriptyline inhibit nitric oxide prostaglandin E2, and hyaluronic acid production in human synovial cells and synovial tissue cultures publication-title: Arthr. Rheum. doi: 10.1002/1529-0131(199912)42:12<2561::AID-ANR8>3.0.CO;2-U – volume: 122 start-page: 109 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0370 article-title: Impact of lithium alone and in combination with antidepressants on cytokine production in vitro publication-title: J. Neural. Transm. (Vienna) doi: 10.1007/s00702-014-1328-6 – volume: 75 start-page: 596 year: 2009 ident: 10.1016/j.imbio.2016.07.001_bib0005 article-title: Amitriptyline attenuates interstitial inflammation and ameliorates the progression of renal fibrosis publication-title: Kidney Int. doi: 10.1038/ki.2008.578 – volume: 27 start-page: 225 year: 1994 ident: 10.1016/j.imbio.2016.07.001_bib0525 article-title: Effect of monoamine reuptake inhibiting antidepressants on major histocompatibility complex expression on macrophages in normal rats and rats with experimental allergic neuritis (EAN) publication-title: Immunopharmacology doi: 10.1016/0162-3109(94)90019-1 – volume: 128 start-page: 1712 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0055 article-title: The antidepressants maprotiline and fluoxetine induce type II autophagic cell death in drug-resistant Burkitt’s lymphoma publication-title: Int. J. Cancer doi: 10.1002/ijc.25477 – volume: 294 start-page: 60 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0460 article-title: Fluoxetine and S-citalopram inhibit M1 activation and promote M2 activation of microglia in vitro publication-title: Neuroscience doi: 10.1016/j.neuroscience.2015.02.028 – volume: 21 start-page: 199 year: 2001 ident: 10.1016/j.imbio.2016.07.001_bib0270 article-title: Anti-inflammatory effects of antidepressants through suppression of the interferon-gamma/interleukin-10 production ratio publication-title: J. Clin. Psychopharmacol. doi: 10.1097/00004714-200104000-00012 – volume: 64 start-page: 1368 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0410 article-title: Effects of co-administration of fluoxetine and risperidone on properties of peritoneal and pleural macrophages in rats subjected to the forced swimming test publication-title: Pharmacol. Rep. doi: 10.1016/S1734-1140(12)70934-9 – volume: 8 start-page: e75426 year: 2013 ident: 10.1016/j.imbio.2016.07.001_bib0340 article-title: Serotonin 5-HT2A receptor activation blocks TNF-α mediated inflammation in vivo publication-title: PLoS One doi: 10.1371/journal.pone.0075426 – volume: 14 start-page: 150 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0465 article-title: Glycogen synthase kinase-3β regulates anti-inflammatory property of fluoxetine publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2012.06.015 – volume: 319 start-page: 287 year: 1997 ident: 10.1016/j.imbio.2016.07.001_bib0425 article-title: In vivo and in vitro clomipramine treatment decreases the migration of macrophages in the rat publication-title: Eur. J. Pharmacol. doi: 10.1016/S0014-2999(96)00984-3 – volume: 35 start-page: 298 year: 1991 ident: 10.1016/j.imbio.2016.07.001_bib0445 article-title: The macrophage theory of depression publication-title: Med. Hypotheses doi: 10.1016/0306-9877(91)90272-Z – year: 2016 ident: 10.1016/j.imbio.2016.07.001_bib0075 article-title: Recovery from major depressive disorder episode after non-pharmacological treatment is associated with normalized cytokine levels publication-title: Acta Psychiatr. Scand. doi: 10.1111/acps.12576 – volume: 130 start-page: 226 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0045 article-title: Immune system to brain signaling: neuropsychopharmacological implications publication-title: Pharmacol. Ther. doi: 10.1016/j.pharmthera.2011.01.014 – volume: 301 start-page: G9 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0245 article-title: Fluoxetine inhibits NF-κB signaling in intestinal epithelial cells and ameliorates experimental colitis and colitis-associated colon cancer in mice publication-title: Am. J. Physiol. Gastrointest. Liver Physiol. doi: 10.1152/ajpgi.00267.2010 – volume: 17 start-page: 677 year: 1995 ident: 10.1016/j.imbio.2016.07.001_bib0210 article-title: Are cytokines associated with neuropsychiatric syndromes in humans? publication-title: Int. J. Immunopharmacol. doi: 10.1016/0192-0561(95)00054-6 – volume: 139 start-page: 150 year: 2010 ident: 10.1016/j.imbio.2016.07.001_bib0295 article-title: Selective serotonin re-uptake inhibitors decrease the cytokine-induced endothelial adhesion molecule expression, the endothelial adhesiveness to monocytes and the circulating levels of vascular adhesion molecules publication-title: Int. J. Cardiol. doi: 10.1016/j.ijcard.2008.10.010 – volume: 21 start-page: 663 year: 1999 ident: 10.1016/j.imbio.2016.07.001_bib0105 article-title: Differential effect of a single high dose of the tricyclic antidepressant imipramine on interleukin-1beta and tumor necrosis factor-alpha secretion following an in vivo lipopolysaccharide challenge in rats publication-title: Int. J. Immunopharmacol. doi: 10.1016/S0192-0561(99)00042-9 – volume: 193 start-page: 4083 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0335 article-title: Imipramine exploits histone deacetylase 11 to increase the IL-12/IL-10 ratio in macrophages infected with antimony-resistant Leishmania donovani and clears organ parasites in experimental infection publication-title: J. Immunol. doi: 10.4049/jimmunol.1400710 – volume: 52 start-page: 6 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0090 article-title: Efficacy of antidepressants as analgesics: a review publication-title: J. Clin. Pharmacol. doi: 10.1177/0091270010394852 – volume: 25 start-page: 485 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0110 article-title: Paroxetine differentially modulates LPS-induced TNFa and IL-6 production in mouse macrophages publication-title: Int. Immunopharmacol. doi: 10.1016/j.intimp.2015.02.029 – volume: 87 start-page: 390 year: 2007 ident: 10.1016/j.imbio.2016.07.001_bib0120 article-title: Serotonergic mechanisms in human allergic contact dermatitis publication-title: Acta Derm. Venereol. doi: 10.2340/00015555-0288 – volume: 14 start-page: 1227 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0375 article-title: Heterogeneity of CNS myeloid cells and their roles in neurodegeneration publication-title: Nat. Neurosci. doi: 10.1038/nn.2923 – volume: 188 start-page: 449 year: 2006 ident: 10.1016/j.imbio.2016.07.001_bib0365 article-title: Antidepressant therapy and C-reactive protein levels publication-title: Br. J. Psychiatry doi: 10.1192/bjp.bp.105.011015 – volume: 34 start-page: 27 year: 1996 ident: 10.1016/j.imbio.2016.07.001_bib0510 article-title: Tricyclic antidepressants inhibit IL-6, IL-1 beta and TNF-alpha release in human blood monocytes and IL-2 and interferon-gamma in T cells publication-title: Immunopharmacology doi: 10.1016/0162-3109(96)00111-7 – volume: 49 start-page: 85 year: 2016 ident: 10.1016/j.imbio.2016.07.001_bib0125 article-title: Modulatory effects of antidepressant classes on the innate and adaptive immune system in depression publication-title: Pharmacopsychiatry doi: 10.1055/s-0042-103159 – volume: 289 start-page: 10466 year: 2014 ident: 10.1016/j.imbio.2016.07.001_bib0475 article-title: Neuroendocrine signaling via the serotonin transporter regulates clearance of apoptotic cells publication-title: J. Biol. Chem. doi: 10.1074/jbc.M113.482299 – volume: 159 start-page: 113 year: 2005 ident: 10.1016/j.imbio.2016.07.001_bib0420 article-title: Peritoneal macrophages express the serotonin transporter publication-title: J. Neuroimmunol. doi: 10.1016/j.jneuroim.2004.10.013 – volume: 129 start-page: 352 year: 2011 ident: 10.1016/j.imbio.2016.07.001_bib0175 article-title: Depression and antidepressants: insights from knockout of dopamine, serotonin or noradrenaline re-uptake transporters publication-title: Pharmacol. Ther. doi: 10.1016/j.pharmthera.2010.12.002 – volume: 41 start-page: 675 year: 1997 ident: 10.1016/j.imbio.2016.07.001_bib0280 article-title: Unaltered monocyte function in patients with major depression before and after three months of antidepressive therapy publication-title: Biol. Psychiatry doi: 10.1016/S0006-3223(96)00176-X – volume: 25 start-page: 767 year: 2001 ident: 10.1016/j.imbio.2016.07.001_bib0300 article-title: The immune system, depression and the action of antidepressants publication-title: Prog. Neuropsychopharmacol. Biol. Psychiatry doi: 10.1016/S0278-5846(01)00155-5 – volume: 21 start-page: 441 year: 2015 ident: 10.1016/j.imbio.2016.07.001_bib0495 article-title: Inhibition of monoamine oxidase A increases recovery after experimental cardiac arrest publication-title: Interact. Cardiovasc. Thorac. Surg. doi: 10.1093/icvts/ivv175 – volume: 34 start-page: 119 year: 2013 ident: 10.1016/j.imbio.2016.07.001_bib0240 article-title: The epidemiology of depression across cultures publication-title: Annu. Rev. Public Health doi: 10.1146/annurev-publhealth-031912-114409 – volume: 66 start-page: 507 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0345 article-title: The biological activity of macrophages in health and disease publication-title: Postepy Hig. Med. Dosw. doi: 10.5604/17322693.1004080 – volume: 18 start-page: 425 year: 2002 ident: 10.1016/j.imbio.2016.07.001_bib0520 article-title: Tricyclic antidepressants prevent the differentiation of monocytes into macrophage-like cells in vitro publication-title: Cell. Biol. Toxicol. doi: 10.1023/A:1020819823917 – volume: 9 start-page: 297 year: 2006 ident: 10.1016/j.imbio.2016.07.001_bib0255 article-title: Effect of amantadine and imipramine on immunological parameters of rats subjected to a forced swimming test publication-title: Int. J. Neuropsychopharmacol. doi: 10.1017/S1461145705005663 – volume: 22 start-page: 370 year: 2000 ident: 10.1016/j.imbio.2016.07.001_bib0285 article-title: Cytokine production and treatment response in major depressive disorder publication-title: Neuropsychopharmacology doi: 10.1016/S0893-133X(99)00134-7 – volume: 19 start-page: 309 year: 2012 ident: 10.1016/j.imbio.2016.07.001_bib0010 article-title: Immunomodulatory effect of sertraline in a rat model of rheumatoid arthritis publication-title: Neuroimmunomodulation doi: 10.1159/000339109 |
| SSID | ssj0019278 |
| Score | 2.4133592 |
| SecondaryResourceType | review_article |
| Snippet | [Display omitted]
Depression is a common disease influencing patients’ quality of life, whose etiology involves complex interactions of environmental, genetic... Graphical abstract Depression is a common disease influencing patients' quality of life, whose etiology involves complex interactions of environmental, genetic and immunological... |
| SourceID | pubmed crossref elsevier |
| SourceType | Index Database Enrichment Source Publisher |
| StartPage | 823 |
| SubjectTerms | Advanced Basic Science Allergy and Immunology Animals Anti-Inflammatory Agents - therapeutic use Antidepressant drugs Antidepressive Agents - therapeutic use Depression - drug therapy Depression - immunology Humans Immune regulation Immune suppression Immunity Immunomodulation Inflammation Macrophages Macrophages - drug effects Macrophages - immunology Neurotransmitter Agents - metabolism Selective serotonin re-uptake inhibitors Serotonin-norepinephrine re-uptake inhibitors Tricyclic antidepressant drugs |
| Title | The role of macrophages in anti-inflammatory activity of antidepressant drugs |
| URI | https://www.clinicalkey.com/#!/content/1-s2.0-S0171298516303205 https://www.clinicalkey.es/playcontent/1-s2.0-S0171298516303205 https://dx.doi.org/10.1016/j.imbio.2016.07.001 https://www.ncbi.nlm.nih.gov/pubmed/27453459 |
| Volume | 222 |
| hasFullText | 1 |
| inHoldings | 1 |
| isFullTextHit | |
| isPrint | |
| link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3JTsMwELUQCIkLYt-RDxwJbRLbTY5VVVRA7QWQuFl2bEMQXUTaA5d-OzOJU4HYJG5ZPFnGk-dxPDOPkLOEt7LIWQboZ5KAWWaCBGAvUNYZZ7VB5lGMthiI3j27fuAPS6RT58JgWKXH_grTS7T2Rxpem41JnjdusdJLlILHIGJkAcdEc8ZaWD__Yr4I8wAHpkJjaBxg67ryUBnjlQ91jhmAYVXB0zPD_Dw6fRh6LjfIuvcZabt6rE2yZEdbZLVikXzbJn3oaopRgnTs6FAhJ9cToERB8xEFveUBGBH0-7BcT6eYyIB8EdgYz_pQWNik5nX2WOyQ-8vuXacXeJaEIANnaRpkNnaYBslVE3TuQuFUqGAWYRlPhIDpFDggiYkyntpUmVgnNmwJrXWauUQwxeJdsjwaj-w-oaCtxKZcK20Uc9ak3GjOtBLQaRGA-gGJau3IzJcQRyaLF1nHij3LUqUSVSqbuLQNQucLoUlVQeP35qxWu6yTQwHOJCD872Kt78Rs4T_JQoayiGRTfjGbAyIWkp8s7-9b7lVWsXgtmOHzmPH08L-XPCJrEboN5V-eY7I8fZ3ZE3B6pvq0tOpTstK-uukNYK8_774DLeoCsg |
| linkProvider | Elsevier |
| linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV1LT8MwDI5gCMEF8X5DDhwpW9ska49oAo3nBZC4RUmTQBF7aB0HLvx27DadQLwkblVr9-G4X53G9kfIQcLbWeQsA_QzScAsM0ECsBco64yz2iDzKGZbXIvuHTu_5_dTpFPXwmBapcf-CtNLtPZ7mt6azWGeN2-w00uUQsQgYmQB59NkhvG4ja599DbJ84AIpoJjkA5QvG49VCZ55T2dYwlgWLXw9NQwP3-ePnx7ThfJgg8a6XF1X0tkyvaXyWxFI_m6Qq5grCmmCdKBoz2FpFyPABMFzfsUDJcH4EUw8L1yQZ1iJQMSRqAwHvW5sLBJzejloVgld6cnt51u4GkSggyipXGQ2dhhHSRXLTC6C4VToYJphGU8EQLmUxCBJCbKeGpTZWKd2LAttNZp5hLBFIvXSKM_6NsNQsFaiU25Vtoo5qxJudGcaSVg1CJA9U0S1daRme8hjlQWz7JOFnuSpUklmlS2cG0blA4nSsOqhcbv4qw2u6yrQwHPJED872rt79Rs4d_JQoayiGRLfvGbTSImmp9c7-9LrldeMXksmOLzmPF067-n3Cdz3durS3l5dn2xTeYjjCHKXz47pDEevdhdiIDGeq_08HcKlAMX |
| openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=The+role+of+macrophages+in+anti-inflammatory+activity+of+antidepressant+drugs&rft.jtitle=Immunobiology+%281979%29&rft.au=Nazimek%2C+Katarzyna&rft.au=Strobel%2C+Spencer&rft.au=Bryniarski%2C+Pawe%C5%82&rft.au=Kozlowski%2C+Michael&rft.date=2017-06-01&rft.pub=Elsevier+GmbH&rft.issn=0171-2985&rft.volume=222&rft.issue=6&rft.spage=823&rft.epage=830&rft_id=info:doi/10.1016%2Fj.imbio.2016.07.001&rft.externalDocID=S0171298516303205 |
| thumbnail_m | http://utb.summon.serialssolutions.com/2.0.0/image/custom?url=https%3A%2F%2Fcdn.clinicalkey.com%2Fck-thumbnails%2F01712985%2FS0171298517X00053%2Fcov150h.gif |