A panel of anti-influenza virus nucleoprotein antibodies selected from phage-displayed synthetic antibody libraries with rapid diagnostic capability to distinguish diverse influenza virus subtypes

• Published in: Scientific reports Vol. 10; no. 1; p. 13318
• Main Authors: Yu, Chung-Ming, Chen, Ing-Chien, Tung, Chao-Ping, Peng, Hung-Pin, Jian, Jhih-Wei, Chiu, Yi-Kai, Tsou, Yueh-Liang, Chen, Hong-Sen, Huang, Yi-Jen, Hsiao, Wesley Wei-Wen, Wang, Yong Alison, Yang, An-Suei
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 07.08.2020; Nature Publishing Group
• Subjects: 631/1647; 631/61; Affinity; Amino acid sequence; Amino acids; Animals; Antibodies; Antibodies, Monoclonal - immunology; Antibodies, Viral - immunology; Antibody libraries; Antigens; Avian flu; Dogs; Enzyme-Linked Immunosorbent Assay; Humanities and Social Sciences; Humans; Immune response (humoral); Immunization; Immunoassay; Immunoassays; Immunodominance; Infections; Influenza; Influenza A virus - immunology; Influenza, Human - diagnosis; Influenza, Human - immunology; Libraries; Madin Darby Canine Kidney Cells; Mice; multidisciplinary; Peptide Library; Phages; Reagents; Science; Science (multidisciplinary); Viral Core Proteins - immunology; Viruses

Immunoassays based on sandwich immuno-complexes of capture and detection antibodies simultaneously binding to the target analytes have been powerful technologies in molecular analyses. Recent developments in single molecule detection technologies enable the detection limit of the sandwich immunoassa...