Insights From Invasive Cardiopulmonary Exercise Testing of Patients With Myalgic Encephalomyelitis/Chronic Fatigue Syndrome

• Published in: Chest Vol. 160; no. 2; pp. 642 - 651
• Main Authors: Joseph, Phillip, Arevalo, Carlo, Oliveira, Rudolf K.F., Faria-Urbina, Mariana, Felsenstein, Donna, Oaklander, Anne Louise, Systrom, David M.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.08.2021; American College of Chest Physicians
• Subjects: Biopsy; dysautonomia; dyspnea; Education and Clinical Practice: Original Research; Exercise Test - methods; exercise testing; Fatigue Syndrome, Chronic - physiopathology; Female; Humans; Male; Middle Aged; Phenotype; physiology; Small Fiber Neuropathy - physiopathology; MM; RAP; iCPET; dysautonomia; physiology; dyspnea; PLF; PAWP; exercise testing; Qc; VO2; SFN; POTS; ME/CFS

Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) affects tens of millions worldwide; the causes of exertional intolerance are poorly understood. The ME/CFS label overlaps with postural orthostatic tachycardia (POTS) and fibromyalgia, and objective evidence of small fiber neuropathy (SFN)...