Blood pressure and calf muscle oxygen extraction during plantar flexion exercise in peripheral artery disease

• Published in: Journal of applied physiology (1985) Vol. 123; no. 1; pp. 2 - 10
• Main Authors: Luck, J. Carter, Miller, Amanda J., Aziz, Faisal, Radtka, John F., Proctor, David N., Leuenberger, Urs A., Sinoway, Lawrence I., Muller, Matthew D.
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 01.07.2017
• Subjects: Aged; Arteries; Arteriosclerosis; Atherosclerosis; Blood pressure; Blood Pressure - physiology; Cardiovascular diseases; Exercise; Exercise - physiology; Fatigue; Female; Heart rate; Hemoglobin; Humans; I.R. radiation; Infrared spectra; Infrared spectroscopy; Intermittent Claudication - diagnosis; Intermittent Claudication - physiopathology; Male; Microvasculature; Middle Aged; Muscle, Skeletal - physiology; Muscles; Near infrared radiation; Oxygen; Oxygen Consumption - physiology; Oxygen uptake; Oxygenation; Patients; Peripheral Arterial Disease - diagnosis; Peripheral Arterial Disease - physiopathology; Physical training; Physiological responses; Pilot Projects; Plant extracts; Plantar flexion; Plantar Plate - physiology; Range of Motion, Articular - physiology; Reduction; Skeletal muscle; Vascular diseases; Vein & artery diseases; heart rate; muscle metabolism; exercise physiology; sympathetic nervous system
• ISSN: 8750-7587; 1522-1601; 1522-1601
• DOI: 10.1152/japplphysiol.01110.2016

Peripheral artery disease (PAD) is an atherosclerotic vascular disease that affects 200 million people worldwide. Although PAD primarily affects large arteries, it is also associated with microvascular dysfunction, an exaggerated blood pressure (BP) response to exercise, and high cardiovascular mort...