High density infill in cracks and protrusions from the articular calcified cartilage in osteoarthritis in standardbred horse carpal bones

• Published in: International journal of molecular sciences Vol. 16; no. 5; pp. 9600 - 9611
• Main Authors: Laverty, Sheila, Lacourt, Mathieu, Gao, Chan, Henderson, Janet E, Boyde, Alan
• Format: Journal Article
• Language: English
• Published: Switzerland MDPI AG 28.04.2015; MDPI
• Subjects: Animals; Arthritis; bone; Calcinosis - complications; Calcinosis - diagnostic imaging; Calcinosis - pathology; Carpal Bones - diagnostic imaging; Carpal Bones - pathology; Cartilage; Cartilage, Articular - diagnostic imaging; Cartilage, Articular - pathology; chondrocyte apoptosis; Communication; dystrophic calcification; Horses; osteoarthritis; Osteoarthritis - complications; Osteoarthritis - diagnostic imaging; Osteoarthritis - pathology; Radiographic Image Interpretation, Computer-Assisted; Stress, Mechanical; Studies; Tomography; X-Ray Microtomography; zone of calcified cartilage

We studied changes in articular calcified cartilage (ACC) and subchondral bone (SCB) in the third carpal bones (C3) of Standardbred racehorses with naturally-occurring repetitive loading-induced osteoarthritis (OA). Two osteochondral cores were harvested from dorsal sites from each of 15 post-mortem...