Reductions in central venous pressure by lower body negative pressure or blood loss elicit similar hemodynamic responses

• Published in: Journal of applied physiology (1985) Vol. 117; no. 2; pp. 131 - 141
• Main Authors: Johnson, Blair D, van Helmond, Noud, Curry, Timothy B, van Buskirk, Camille M, Convertino, Victor A, Joyner, Michael J
• Format: Journal Article
• Language: English
• Published: United States American Physiological Society 15.07.2014
• Subjects: Adult; Arginine Vasopressin - metabolism; Arterial Pressure - physiology; Blood; Blood Gas Analysis - methods; Catecholamines - metabolism; Central Venous Pressure - physiology; Heart Rate - physiology; Hematocrit - methods; Hemodynamics - physiology; Hemoglobins - metabolism; Hemorrhage - metabolism; Hemorrhage - physiopathology; Humans; Lower Body Negative Pressure - methods; Male; Norepinephrine - metabolism; Pressure; Regression analysis; Veins & arteries; blood pressure; heart rate; central hypovolemia; hemorrhage; stroke volume

The purpose of this study was to compare hemodynamic and blood analyte responses to reduced central venous pressure (CVP) and pulse pressure (PP) elicited during graded lower body negative pressure (LBNP) to those observed during graded blood loss (BL) in conscious humans. We hypothesized that the s...