Mineralocorticoid receptors in control of emotional arousal and fear memory
The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are involved in processing of stressful events. A disbalance of MR:GR functions is thought to promote stress-related disorders. Here we studied...
Saved in:
Published in | Hormones and behavior Vol. 56; no. 2; pp. 232 - 238 |
---|---|
Main Authors | , , , , |
Format | Journal Article |
Language | English |
Published |
Amsterdam
Elsevier Inc
01.08.2009
Elsevier Elsevier BV |
Subjects | |
Online Access | Get full text |
Cover
Loading…
Abstract | The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are involved in processing of stressful events. A disbalance of MR:GR functions is thought to promote stress-related disorders. Here we studied the effect of stress on emotional and cognitive behaviors in mice with forebrain-specific inactivation of the MR gene (MR
CaMKCre, 4 months old; and control littermates). MR
CaMKCre mice responded to prior stress (5 min of restraint) with higher arousal and less locomotor activity in an exploration task. A fear conditioning paradigm allowed assessing in one experimental procedure both context- and cue-related fear. During conditioning, MR
CaMKCre mice expressed more cue-related freezing. During memory test, contextual freezing remained potentiated, while control mice distinguished between cue (more freezing) and context episodes (less freezing) in the second memory test. At this time, plasma corticosterone levels of MR
CaMKCre mice were 40% higher than in controls. We conclude that control of emotional arousal and adaptive behaviors is lost in the absence of forebrain MR, and thus, anxiety-related responses are and remain augmented. We propose that such a disbalance in MR:GR functions in MR
CaMKCre mice provides the conditions for an animal model for anxiety-related disorders. |
---|---|
AbstractList | The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are involved in processing of stressful events. A disbalance of MR:GR functions is thought to promote stress-related disorders. Here we studied the effect of stress on emotional and cognitive behaviors in mice with forebrain-specific inactivation of the MR gene (MR
CaMKCre, 4 months old; and control littermates). MR
CaMKCre mice responded to prior stress (5 min of restraint) with higher arousal and less locomotor activity in an exploration task. A fear conditioning paradigm allowed assessing in one experimental procedure both context- and cue-related fear. During conditioning, MR
CaMKCre mice expressed more cue-related freezing. During memory test, contextual freezing remained potentiated, while control mice distinguished between cue (more freezing) and context episodes (less freezing) in the second memory test. At this time, plasma corticosterone levels of MR
CaMKCre mice were 40% higher than in controls. We conclude that control of emotional arousal and adaptive behaviors is lost in the absence of forebrain MR, and thus, anxiety-related responses are and remain augmented. We propose that such a disbalance in MR:GR functions in MR
CaMKCre mice provides the conditions for an animal model for anxiety-related disorders. The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are involved in processing of stressful events. A disbalance of MR:GR functions is thought to promote stress-related disorders. Here we studied the effect of stress on emotional and cognitive behaviors in mice with forebrain-specific inactivation of the MR gene (MR(CaMKCre), 4 months old; and control littermates). MR(CaMKCre) mice responded to prior stress (5 min of restraint) with higher arousal and less locomotor activity in an exploration task. A fear conditioning paradigm allowed assessing in one experimental procedure both context- and cue-related fear. During conditioning, MR(CaMKCre) mice expressed more cue-related freezing. During memory test, contextual freezing remained potentiated, while control mice distinguished between cue (more freezing) and context episodes (less freezing) in the second memory test. At this time, plasma corticosterone levels of MR(CaMKCre) mice were 40% higher than in controls. We conclude that control of emotional arousal and adaptive behaviors is lost in the absence of forebrain MR, and thus, anxiety-related responses are and remain augmented. We propose that such a disbalance in MR:GR functions in MR(CaMKCre) mice provides the conditions for an animal model for anxiety-related disorders. The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are involved in processing of stressful events. A disbalance of MR:GR functions is thought to promote stress-related disorders. Here we studied the effect of stress on emotional and cognitive behaviors in mice with forebrain-specific inactivation of the MR gene (MR super(C) super(a) super(M) super(K) super(C) super(r) super(e), 4 months old; and control littermates). MR super(C) super(a) super(M) super(K) super(C) super(r) super(e) mice responded to prior stress (5 min of restraint) with higher arousal and less locomotor activity in an exploration task. A fear conditioning paradigm allowed assessing in one experimental procedure both context- and cue-related fear. During conditioning, MR super(C) super(a) super(M) super(K) super(C) super(r) super(e) mice expressed more cue-related freezing. During memory test, contextual freezing remained potentiated, while control mice distinguished between cue (more freezing) and context episodes (less freezing) in the second memory test. At this time, plasma corticosterone levels of MR super(C) super(a) super(M) super(K) super(C) super(r) super(e) mice were 40% higher than in controls. We conclude that control of emotional arousal and adaptive behaviors is lost in the absence of forebrain MR, and thus, anxiety-related responses are and remain augmented. We propose that such a disbalance in MR:GR functions in MR super(C) super(a) super(M) super(K) super(C) super(r) super(e) mice provides the conditions for an animal model for anxiety-related disorders. The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are involved in processing of stressful events. A disbalance of MR:GR functions is thought to promote stress-related disorders. Here we studied the effect of stress on emotional and cognitive behaviors in mice with forebrain-specific inactivation of the MR gene (MRCaMKCre , 4 months old; and control littermates). MRCaMKCre mice responded to prior stress (5 min of restraint) with higher arousal and less locomotor activity in an exploration task. A fear conditioning paradigm allowed assessing in one experimental procedure both context- and cue-related fear. During conditioning, MRCaMKCre mice expressed more cue-related freezing. During memory test, contextual freezing remained potentiated, while control mice distinguished between cue (more freezing) and context episodes (less freezing) in the second memory test. At this time, plasma corticosterone levels of MRCaMKCre mice were 40% higher than in controls. We conclude that control of emotional arousal and adaptive behaviors is lost in the absence of forebrain MR, and thus, anxiety-related responses are and remain augmented. We propose that such a disbalance in MR:GR functions in MRCaMKCre mice provides the conditions for an animal model for anxiety-related disorders. [PUBLICATION ABSTRACT] |
Author | Brinks, V. Gass, P. de Kloet, E.R. Oitzl, M.S. Berger, S. |
Author_xml | – sequence: 1 givenname: V. surname: Brinks fullname: Brinks, V. organization: Division of Medical Pharmacology, LACDR/LUMC, Gorlaeus Laboratories, PO Box 9502, Leiden University, 2300 RA Leiden, The Netherlands – sequence: 2 givenname: S. surname: Berger fullname: Berger, S. organization: German Cancer Research Center, Division Molecular Biology of the Cell I, Im Neuenheimer Feld 280, Heidelberg, Germany – sequence: 3 givenname: P. surname: Gass fullname: Gass, P. organization: Central Institute of Mental Health, J 5, D-68159, Mannheim, Germany – sequence: 4 givenname: E.R. surname: de Kloet fullname: de Kloet, E.R. organization: Division of Medical Pharmacology, LACDR/LUMC, Gorlaeus Laboratories, PO Box 9502, Leiden University, 2300 RA Leiden, The Netherlands – sequence: 5 givenname: M.S. surname: Oitzl fullname: Oitzl, M.S. email: m.oitzl@lacdr.leidenuniv.nl organization: Division of Medical Pharmacology, LACDR/LUMC, Gorlaeus Laboratories, PO Box 9502, Leiden University, 2300 RA Leiden, The Netherlands |
BackLink | http://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&idt=21810044$$DView record in Pascal Francis https://www.ncbi.nlm.nih.gov/pubmed/19447109$$D View this record in MEDLINE/PubMed |
BookMark | eNqFkU9r3DAQxUVJaDZpP0GhmEJ7szsjS7J96CGE_iMpvbTQm5DlMdFiS1vJW9hvH7m7tNBDcxoG_ebpzbxLduaDJ8ZeIFQIqN5uq8N9T_cVB-gqkBVA_YRtEDpZqlY1Z2wDgG0pQf24YJcpbXOLUoin7AI7IZpMbtjtF-cpminYEBdngxuKSJZ2S4ipcL6wwS8xTEUYC5rD4oI3U2Fi2Ke1-qEYycRizm_x8Iydj2ZK9PxUr9j3D--_3Xwq775-_HxzfVdaibiUBhUXNXDDCaSEHhWoJjsdBoGtrPt-sF3fjShwbMdetiiNbE1LnCuEelD1FXtz1N3F8HNPadGzS5amyXjKxrRqJBd500dBDijqDpsMvvoH3IZ9zKsmnU_VNp3CVa0-QjaGlCKNehfdbOJBI-g1Eb3VvxPRayIapM6J5KmXJ-l9P9Pwd-YUQQZenwCTrJnGaLx16Q_HsUUAsX7_7shRPu0vR1En68hbGlxObNFDcP818gDRxKqK |
CODEN | HOBEAO |
CitedBy_id | crossref_primary_10_1016_j_neurobiolaging_2014_09_008 crossref_primary_10_1080_10253890_2023_2204366 crossref_primary_10_1016_j_psyneuen_2013_11_010 crossref_primary_10_1016_j_nlm_2012_04_006 crossref_primary_10_1016_j_bbr_2012_10_003 crossref_primary_10_1016_j_psyneuen_2010_10_003 crossref_primary_10_1016_j_neubiorev_2009_07_006 crossref_primary_10_1016_j_tics_2015_12_003 crossref_primary_10_1038_mp_2016_16 crossref_primary_10_1530_JOE_17_0155 crossref_primary_10_1016_j_neuropharm_2020_108337 crossref_primary_10_1016_j_neuropharm_2012_05_048 crossref_primary_10_1210_en_2009_0753 crossref_primary_10_1016_j_ejphar_2009_10_017 crossref_primary_10_1016_j_psyneuen_2018_09_036 crossref_primary_10_1016_j_bbr_2010_08_019 crossref_primary_10_3389_fnbeh_2020_00012 crossref_primary_10_1007_s00213_016_4380_0 crossref_primary_10_1016_j_psyneuen_2010_05_011 crossref_primary_10_1016_j_psyneuen_2012_09_014 crossref_primary_10_1016_j_bbr_2010_06_001 crossref_primary_10_1016_j_neubiorev_2011_01_005 crossref_primary_10_1016_j_yhbeh_2011_11_008 crossref_primary_10_1002_pchj_58 crossref_primary_10_1038_npp_2014_181 crossref_primary_10_3389_fnbeh_2019_00181 crossref_primary_10_1016_j_nlm_2010_08_006 crossref_primary_10_1002_mgg3_1345 crossref_primary_10_1016_j_brainres_2011_03_055 crossref_primary_10_1016_j_pnpbp_2010_06_025 crossref_primary_10_1111_ejn_12337 crossref_primary_10_1007_s00213_019_05388_9 crossref_primary_10_1111_j_1460_9568_2012_08237_x crossref_primary_10_1038_s41398_022_02118_2 crossref_primary_10_1016_j_bbr_2022_113938 crossref_primary_10_1038_s41598_020_69968_y crossref_primary_10_1371_journal_pone_0086236 crossref_primary_10_1038_mp_2012_123 crossref_primary_10_1016_j_ejphar_2013_04_053 crossref_primary_10_1016_j_mce_2021_111501 crossref_primary_10_1016_j_psyneuen_2014_10_022 crossref_primary_10_1152_ajpendo_00227_2011 crossref_primary_10_1016_j_nlm_2018_10_002 crossref_primary_10_1007_s10571_011_9774_2 crossref_primary_10_1124_pr_112_005892 crossref_primary_10_1016_j_steroids_2014_08_014 |
Cites_doi | 10.1073/pnas.0606067104 10.1016/j.tics.2006.02.002 10.1002/j.1939-4640.2004.tb03170.x 10.1196/annals.1296.039 10.1016/S0306-4530(03)00090-8 10.1016/S0079-6123(07)67019-8 10.1046/j.1460-9568.2003.02436.x 10.1023/A:1022010904600 10.1111/j.1460-9568.1996.tb01264.x 10.1016/j.bandc.2007.02.007 10.1038/ncpendmet0403 10.1038/nrn1683 10.1258/002367700780387714 10.1016/S0031-9384(01)00518-2 10.1016/0306-4530(95)00003-7 10.1196/annals.1286.037 10.1073/pnas.0503878102 10.1017/S1461145703004000 10.1038/sj.npp.1300898 10.1152/ajpendo.00721.2007 10.1111/j.1460-9568.2008.06220.x 10.1111/j.1460-9568.2007.05427.x 10.1016/j.expneurol.2008.12.011 10.1152/ajpendo.00521.2004 10.1098/rspb.2006.3704 10.1016/j.tics.2007.08.006 10.1016/j.ejphar.2007.07.072 10.1016/0306-4530(94)00069-7 10.1002/hipo.20467 10.1523/JNEUROSCI.20-18-06983.2000 10.1016/S0166-2236(99)01438-1 10.1073/pnas.231313998 10.1016/j.biopsych.2006.09.009 10.1016/j.bbr.2005.06.020 10.1016/S0149-7634(01)00002-1 10.1016/S0006-8993(99)01054-9 10.1016/j.bbr.2007.08.025 10.1155/2007/90163 10.1016/j.nlm.2006.02.001 10.1111/j.1460-9568.1994.tb00604.x 10.1016/S0304-3940(99)00858-7 10.1016/j.bbi.2007.07.012 10.1037/0735-7044.106.1.62 10.1073/pnas.0507572102 10.1159/000125210 |
ContentType | Journal Article |
Copyright | 2009 Elsevier Inc. 2009 INIST-CNRS Copyright © 2009 Elsevier B.V. All rights reserved. |
Copyright_xml | – notice: 2009 Elsevier Inc. – notice: 2009 INIST-CNRS – notice: Copyright © 2009 Elsevier B.V. All rights reserved. |
DBID | IQODW CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QG 7TK K9. 7X8 |
DOI | 10.1016/j.yhbeh.2009.05.003 |
DatabaseName | Pascal-Francis Medline MEDLINE MEDLINE (Ovid) MEDLINE MEDLINE PubMed CrossRef Animal Behavior Abstracts Neurosciences Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
DatabaseTitle | MEDLINE Medline Complete MEDLINE with Full Text PubMed MEDLINE (Ovid) CrossRef ProQuest Health & Medical Complete (Alumni) Neurosciences Abstracts Animal Behavior Abstracts MEDLINE - Academic |
DatabaseTitleList | MEDLINE Neurosciences Abstracts ProQuest Health & Medical Complete (Alumni) MEDLINE - Academic |
Database_xml | – sequence: 1 dbid: NPM name: PubMed url: https://proxy.k.utb.cz/login?url=http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?db=PubMed sourceTypes: Index Database – sequence: 2 dbid: EIF name: MEDLINE url: https://proxy.k.utb.cz/login?url=https://www.webofscience.com/wos/medline/basic-search sourceTypes: Index Database |
DeliveryMethod | fulltext_linktorsrc |
Discipline | Medicine Anatomy & Physiology |
EISSN | 1095-6867 |
EndPage | 238 |
ExternalDocumentID | 1807807451 10_1016_j_yhbeh_2009_05_003 19447109 21810044 S0018506X09001093 |
Genre | Research Support, Non-U.S. Gov't Journal Article Feature |
GroupedDBID | --- --K --M -DZ -~X .55 .GJ .~1 0R~ 1B1 1RT 1~. 1~5 29I 4.4 457 4G. 53G 5GY 5VS 7-5 71M 8P~ 9JM 9JO AACTN AADFP AADPK AAEDT AAEDW AAGJA AAGUQ AAIAV AAIKJ AAKOC AALRI AAOAW AAQFI AAQXK AAXLA AAXUO ABCQJ ABFNM ABFRF ABGSF ABIVO ABJNI ABMAC ABOYX ABUDA ABXDB ABYKQ ACDAQ ACGFS ACNCT ACPRK ACRLP ACXNI ADBBV ADEZE ADFGL ADMUD ADUVX AEBSH AEFWE AEHWI AEKER AENEX AFKWA AFTJW AFXIZ AFYLN AGHFR AGRDE AGUBO AGWIK AGYEJ AHHHB AHMBA AHPSJ AIEXJ AIKHN AITUG AJBFU AJOXV ALMA_UNASSIGNED_HOLDINGS AMFUW AMRAJ ASPBG AVWKF AXJTR AZFZN BKOJK BLXMC C45 CAG COF CS3 DM4 DOVZS EBS EFBJH EFLBG EJD EO8 EO9 EP2 EP3 F5P FDB FEDTE FGOYB FIRID FNPLU FYGXN G-2 G-Q GBLVA HLW HMQ HMW HVGLF HZ~ H~9 IHE J1W KOM LG5 LX2 M2U M3U M41 MO0 MOBAO MVM N9A O-L O9- OAUVE OKEIE OVD OZT P-8 P-9 PC. PQQKQ Q38 R2- RIG ROL RPZ SBG SCC SDF SDG SDP SES SEW SNS SPCBC SPS SSB SSN SSU SSY SSZ T5K TEORI TWZ UAP UNMZH UQL VQP WH7 WUQ X7M XOL XPP ZGI ZKB ZMT ZU3 ~02 ~G- 08R AAPBV AAUGY ABPIF ABPTK IQODW AAXKI AFJKZ AKRWK CGR CUY CVF ECM EIF NPM AAYXX CITATION 7QG 7TK K9. 7X8 |
ID | FETCH-LOGICAL-c511t-a1624302a2e0550b16067018dd41853bbdc9b9f141f8fb5815a58a8e226103d63 |
IEDL.DBID | AIKHN |
ISSN | 0018-506X |
IngestDate | Sat Aug 17 02:04:56 EDT 2024 Sun Sep 29 07:14:52 EDT 2024 Fri Sep 13 04:07:04 EDT 2024 Thu Sep 26 19:08:39 EDT 2024 Sat Sep 28 07:46:27 EDT 2024 Sun Oct 22 16:09:15 EDT 2023 Fri Feb 23 02:27:52 EST 2024 |
IsPeerReviewed | true |
IsScholarly | true |
Issue | 2 |
Keywords | Forebrain Emotion Mineralocorticoid receptor Unconditioned behavior Stress Fear conditioning Affect affectivity Memory Central nervous system Emotion emotionality Prosencephalon Fear Arousal Behavior Conditioning |
Language | English |
License | CC BY 4.0 |
LinkModel | DirectLink |
MergedId | FETCHMERGED-LOGICAL-c511t-a1624302a2e0550b16067018dd41853bbdc9b9f141f8fb5815a58a8e226103d63 |
Notes | ObjectType-Article-2 SourceType-Scholarly Journals-1 ObjectType-Feature-1 content type line 23 ObjectType-Article-1 ObjectType-Feature-2 |
PMID | 19447109 |
PQID | 194879614 |
PQPubID | 45959 |
PageCount | 7 |
ParticipantIDs | proquest_miscellaneous_67524154 proquest_miscellaneous_20143917 proquest_journals_194879614 crossref_primary_10_1016_j_yhbeh_2009_05_003 pubmed_primary_19447109 pascalfrancis_primary_21810044 elsevier_sciencedirect_doi_10_1016_j_yhbeh_2009_05_003 |
PublicationCentury | 2000 |
PublicationDate | 2009-08-01 |
PublicationDateYYYYMMDD | 2009-08-01 |
PublicationDate_xml | – month: 08 year: 2009 text: 2009-08-01 day: 01 |
PublicationDecade | 2000 |
PublicationPlace | Amsterdam |
PublicationPlace_xml | – name: Amsterdam – name: United States – name: New York |
PublicationTitle | Hormones and behavior |
PublicationTitleAlternate | Horm Behav |
PublicationYear | 2009 |
Publisher | Elsevier Inc Elsevier Elsevier BV |
Publisher_xml | – name: Elsevier Inc – name: Elsevier – name: Elsevier BV |
References | Atkinson, Wood, Castrique, Kershaw, Wiles, Lightman (bib1) 2008; 294 Mikics, Kruk, Haller (bib28) 2004; 29 Herrero, Sandi, Venero (bib17) 2006; 86 Lupien, Maheu, Tu, Fiocco, Schramek (bib27) 2007; 65 Brinks, van der Mark, de Kloet, Oitzl (bib5) 2007; 2007 Yau, Noble, Seckl (bib46) 1999; 277 Joels, Pu, Wiegert, Oitzl, Krugers (bib19) 2006; 10 Oitzl, de Kloet (bib30) 1992; 106 Xing, Russell, Webster, Post (bib45) 2004; 7 Ferguson, Sapolsky (bib14) 2008; 18 Wright, Conrad (bib44) 2008; 187 de Kloet, Joels, Holsboer (bib9) 2005; 6 Feldman, Weidenfeld (bib13) 1999; 821 Ohl, Roedel, Binder, Holsboer (bib29) 2003; 17 Oitzl, van Haarst, Sutanto, de Kloet (bib32) 1995; 20 Bowers, Bilbo, Dhabhar, Nelson (bib3) 2008; 22 Urani, Gass (bib41) 2003; 1007 van West, Van Den, Del-Favero, Souery, Norrback, Van, Sluijs, Adolfsson, Mendlewicz, Deboutte, Van, Claes (bib43) 2006; 31 Gass, Reichardt, Strekalova, Henn, Tronche (bib16) 2001; 73 Korte, de Boer, de Kloet, Bohus (bib25) 1995; 20 Korte (bib24) 2001; 25 Kellner, Wiedemann (bib22) 2008; 583 de Kloet, Oitzl, Joels (bib8) 1999; 22 Taylor, Liberzon (bib39) 2007; 11 Olijslagers, de Kloet, Elgersma, van Woerden, Joels, Karst (bib34) 2008; 27 Brinks, Van der Mark, de Kloet, Oitzl (bib4) 2007 Oitzl, Reichardt, Joels, de Kloet (bib33) 2001; 98 de Kloet, Derijk, Meijer (bib10) 2007; 3 Oitzl, Fluttert, de Kloet (bib31) 1994; 6 Sandi, Venero, Guaza (bib38) 1996; 8 Dong, Salva, Sottas, Niu, Holmes, Hardy (bib11) 2004; 25 van Haarst, Oitzl, de Kloet (bib42) 1997; 22 Lai, Horsburgh, Bae, Carter, Stenvers, Fowler, Yau, Gomez-Sanchez, Holmes, Kenyon, Seckl, Macleod (bib26) 2007; 25 Fluttert, Dalm, Oitzl (bib15) 2000; 34 Kabbaj, Devine, Savage, Akil (bib20) 2000; 20 Donley, Schulkin, Rosen (bib12) 2005; 164 Rozeboom, Akil, Seasholtz (bib37) 2007; 104 Tronel, Alberini (bib40) 2007; 62 Karst, Berger, Turiault, Tronche, Schutz, Joels (bib21) 2005; 102 Hodgson, Meddle, Roberts, Buchanan, Evans, Metzdorf, Gahr, Healy (bib18) 2007; 274 Ratka, Sutanto, Bloemers, de Kloet (bib36) 1989; 50 Pace, Spencer (bib35) 2005; 288 Brinks, de Kloet, Oitzl (bib7) 2009; 216 Kitraki, Kremmyda, Youlatos, Alexis, Kittas (bib23) 2004; 1018 Berger, Wolfer, Selbach, Alter, Erdmann, Reichardt, Chepkova, Welzl, Haas, Lipp, Schutz (bib2) 2006; 103 Brinks, de Kloet, Oitzl (bib6) 2008; 167 Urani (10.1016/j.yhbeh.2009.05.003_bib41) 2003; 1007 de Kloet (10.1016/j.yhbeh.2009.05.003_bib9) 2005; 6 Wright (10.1016/j.yhbeh.2009.05.003_bib44) 2008; 187 de Kloet (10.1016/j.yhbeh.2009.05.003_bib10) 2007; 3 Feldman (10.1016/j.yhbeh.2009.05.003_bib13) 1999; 821 Brinks (10.1016/j.yhbeh.2009.05.003_bib7) 2009; 216 Xing (10.1016/j.yhbeh.2009.05.003_bib45) 2004; 7 Ohl (10.1016/j.yhbeh.2009.05.003_bib29) 2003; 17 van Haarst (10.1016/j.yhbeh.2009.05.003_bib42) 1997; 22 Karst (10.1016/j.yhbeh.2009.05.003_bib21) 2005; 102 Pace (10.1016/j.yhbeh.2009.05.003_bib35) 2005; 288 Kellner (10.1016/j.yhbeh.2009.05.003_bib22) 2008; 583 Hodgson (10.1016/j.yhbeh.2009.05.003_bib18) 2007; 274 Brinks (10.1016/j.yhbeh.2009.05.003_bib6) 2008; 167 Korte (10.1016/j.yhbeh.2009.05.003_bib24) 2001; 25 Gass (10.1016/j.yhbeh.2009.05.003_bib16) 2001; 73 Mikics (10.1016/j.yhbeh.2009.05.003_bib28) 2004; 29 Kitraki (10.1016/j.yhbeh.2009.05.003_bib23) 2004; 1018 Fluttert (10.1016/j.yhbeh.2009.05.003_bib15) 2000; 34 Atkinson (10.1016/j.yhbeh.2009.05.003_bib1) 2008; 294 Yau (10.1016/j.yhbeh.2009.05.003_bib46) 1999; 277 Brinks (10.1016/j.yhbeh.2009.05.003_bib4) 2007 Kabbaj (10.1016/j.yhbeh.2009.05.003_bib20) 2000; 20 Donley (10.1016/j.yhbeh.2009.05.003_bib12) 2005; 164 Herrero (10.1016/j.yhbeh.2009.05.003_bib17) 2006; 86 de Kloet (10.1016/j.yhbeh.2009.05.003_bib8) 1999; 22 Rozeboom (10.1016/j.yhbeh.2009.05.003_bib37) 2007; 104 Bowers (10.1016/j.yhbeh.2009.05.003_bib3) 2008; 22 Lai (10.1016/j.yhbeh.2009.05.003_bib26) 2007; 25 Joels (10.1016/j.yhbeh.2009.05.003_bib19) 2006; 10 Ferguson (10.1016/j.yhbeh.2009.05.003_bib14) 2008; 18 Ratka (10.1016/j.yhbeh.2009.05.003_bib36) 1989; 50 Berger (10.1016/j.yhbeh.2009.05.003_bib2) 2006; 103 Dong (10.1016/j.yhbeh.2009.05.003_bib11) 2004; 25 Oitzl (10.1016/j.yhbeh.2009.05.003_bib32) 1995; 20 Oitzl (10.1016/j.yhbeh.2009.05.003_bib33) 2001; 98 Tronel (10.1016/j.yhbeh.2009.05.003_bib40) 2007; 62 Oitzl (10.1016/j.yhbeh.2009.05.003_bib30) 1992; 106 Taylor (10.1016/j.yhbeh.2009.05.003_bib39) 2007; 11 van West (10.1016/j.yhbeh.2009.05.003_bib43) 2006; 31 Lupien (10.1016/j.yhbeh.2009.05.003_bib27) 2007; 65 Brinks (10.1016/j.yhbeh.2009.05.003_bib5) 2007; 2007 Oitzl (10.1016/j.yhbeh.2009.05.003_bib31) 1994; 6 Olijslagers (10.1016/j.yhbeh.2009.05.003_bib34) 2008; 27 Sandi (10.1016/j.yhbeh.2009.05.003_bib38) 1996; 8 Korte (10.1016/j.yhbeh.2009.05.003_bib25) 1995; 20 |
References_xml | – volume: 164 start-page: 197 year: 2005 end-page: 205 ident: bib12 article-title: Glucocorticoid receptor antagonism in the basolateral amygdala and ventral hippocampus interferes with long-term memory of contextual fear publication-title: Behav. Brain Res. contributor: fullname: Rosen – volume: 25 start-page: 1832 year: 2007 end-page: 1842 ident: bib26 article-title: Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia publication-title: Eur. J. Neurosci. contributor: fullname: Macleod – volume: 29 start-page: 618 year: 2004 end-page: 635 ident: bib28 article-title: Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats publication-title: Psychoneuroendocrinology contributor: fullname: Haller – volume: 20 start-page: 6983 year: 2000 end-page: 6988 ident: bib20 article-title: Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules publication-title: J. Neurosci. contributor: fullname: Akil – volume: 102 start-page: 19204 year: 2005 end-page: 19207 ident: bib21 article-title: Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone publication-title: Proc. Natl. Acad. Sci. U. S. A contributor: fullname: Joels – volume: 20 start-page: 385 year: 1995 end-page: 394 ident: bib25 article-title: Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze publication-title: Psychoneuroendocrinology contributor: fullname: Bohus – volume: 294 start-page: E1011 year: 2008 end-page: E1022 ident: bib1 article-title: Corticosteroids mediate fast feedback of the rat hypothalamic–pituitary–adrenal axis via the mineralocorticoid receptor publication-title: Am. J. Physiol. Endocrinol. Metab. contributor: fullname: Lightman – volume: 583 start-page: 372 year: 2008 end-page: 378 ident: bib22 article-title: Mineralocorticoid receptors in brain, in health and disease: possibilities for new pharmacotherapy publication-title: Eur. J. Pharmacol. contributor: fullname: Wiedemann – volume: 25 start-page: 973 year: 2004 end-page: 981 ident: bib11 article-title: Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress publication-title: J. Androl contributor: fullname: Hardy – volume: 11 start-page: 413 year: 2007 end-page: 418 ident: bib39 article-title: Neural correlates of emotion regulation in psychopathology publication-title: Trends Cogn. Sci. contributor: fullname: Liberzon – volume: 62 start-page: 33 year: 2007 end-page: 39 ident: bib40 article-title: Persistent disruption of a traumatic memory by postretrieval inactivation of glucocorticoid receptors in the amygdala publication-title: Biol. Psychiatry contributor: fullname: Alberini – volume: 22 start-page: 422 year: 1999 end-page: 426 ident: bib8 article-title: Stress and cognition: are corticosteroids good or bad guys? publication-title: Trends Neurosci. contributor: fullname: Joels – volume: 6 start-page: 1072 year: 1994 end-page: 1079 ident: bib31 article-title: The effect of corticosterone on reactivity to spatial novelty is mediated by central mineralocorticosteroid receptors publication-title: Eur. J. Neurosci. contributor: fullname: de Kloet – volume: 20 start-page: 655 year: 1995 end-page: 675 ident: bib32 article-title: Corticosterone, brain mineralocorticoid receptors (MRs) and the activity of the hypothalamic–pituitary–adrenal (HPA) axis: the Lewis rat as an example of increased central MR capacity and a hyporesponsive HPA axis publication-title: Psychoneuroendocrinology contributor: fullname: de Kloet – volume: 187 start-page: 41 year: 2008 end-page: 47 ident: bib44 article-title: Enriched environment prevents chronic stress-induced spatial learning and memory deficits publication-title: Behav. Brain Res. contributor: fullname: Conrad – volume: 216 start-page: 375 year: 2009 end-page: 382 ident: bib7 article-title: Corticosterone facilitates extinction of fear memory in BALB/c mice but strengthens cue related fear in C57BL/6 mice publication-title: Exp. Neurol. contributor: fullname: Oitzl – volume: 6 start-page: 463 year: 2005 end-page: 475 ident: bib9 article-title: Stress and the brain: from adaptation to disease publication-title: Nat. Rev. Neurosci. contributor: fullname: Holsboer – volume: 10 start-page: 152 year: 2006 end-page: 158 ident: bib19 article-title: Learning under stress: how does it work? publication-title: Trends Cogn. Sci. contributor: fullname: Krugers – volume: 98 start-page: 12790 year: 2001 end-page: 12795 ident: bib33 article-title: . Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory publication-title: Proc. Natl. Acad. Sci. U. S. A contributor: fullname: de Kloet – volume: 25 start-page: 117 year: 2001 end-page: 142 ident: bib24 article-title: Corticosteroids in relation to fear, anxiety and psychopathology publication-title: Neurosci. Biobehav. Rev. contributor: fullname: Korte – volume: 3 start-page: 168 year: 2007 end-page: 179 ident: bib10 article-title: Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression? publication-title: Nat. Clin. Pract. Endocrinol. Metab. contributor: fullname: Meijer – volume: 22 start-page: 1323 year: 1997 end-page: 1328 ident: bib42 article-title: Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus publication-title: Neurochem. Res. contributor: fullname: de Kloet – volume: 288 start-page: E1082 year: 2005 end-page: E1088 ident: bib35 article-title: Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor publication-title: Am. J. Physiol. Endocrinol. Metab. contributor: fullname: Spencer – volume: 22 start-page: 105 year: 2008 end-page: 113 ident: bib3 article-title: Stressor-specific alterations in corticosterone and immune responses in mice publication-title: Brain Behav. Immunol. contributor: fullname: Nelson – volume: 73 start-page: 811 year: 2001 end-page: 825 ident: bib16 article-title: Mice with targeted mutations of glucocorticoid and mineralocorticoid receptors: models for depression and anxiety? publication-title: Physiol. Behav. contributor: fullname: Tronche – volume: 18 start-page: 1103 year: 2008 end-page: 1111 ident: bib14 article-title: Overexpression of mineralocorticoid and transdominant glucocorticoid receptor blocks the impairing effects of glucocorticoids on memory publication-title: Hippocampus contributor: fullname: Sapolsky – volume: 86 start-page: 150 year: 2006 end-page: 159 ident: bib17 article-title: Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors publication-title: Neurobiol. Learn. Mem. contributor: fullname: Venero – volume: 274 start-page: 239 year: 2007 end-page: 245 ident: bib18 article-title: Spatial ability is impaired and hippocampal mineralocorticoid receptor mRNA expression reduced in zebra finches ( publication-title: Proc. Biol. Sci. contributor: fullname: Healy – volume: 31 start-page: 620 year: 2006 end-page: 627 ident: bib43 article-title: Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression publication-title: Neuropsychopharmacology contributor: fullname: Claes – volume: 821 start-page: 33 year: 1999 end-page: 37 ident: bib13 article-title: Glucocorticoid receptor antagonists in the hippocampus modify the negative feedback following neural stimuli publication-title: Brain Res. contributor: fullname: Weidenfeld – volume: 34 start-page: 372 year: 2000 end-page: 378 ident: bib15 article-title: A refined method for sequential blood sampling by tail incision in rats publication-title: Lab. Anim contributor: fullname: Oitzl – volume: 65 start-page: 209 year: 2007 end-page: 237 ident: bib27 article-title: The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition publication-title: Brain Cogn. contributor: fullname: Schramek – volume: 7 start-page: 143 year: 2004 end-page: 153 ident: bib45 article-title: Decreased expression of mineralocorticoid receptor mRNA in the prefrontal cortex in schizophrenia and bipolar disorder publication-title: Int. J. Neuropsychopharmacol. contributor: fullname: Post – volume: 2007 start-page: 90163 year: 2007 ident: bib5 article-title: Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition publication-title: Neural Plast. contributor: fullname: Oitzl – volume: 1007 start-page: 379 year: 2003 end-page: 393 ident: bib41 article-title: Corticosteroid receptor transgenic mice: models for depression? publication-title: Ann. N. Y. Acad. Sci. contributor: fullname: Gass – volume: 50 start-page: 117 year: 1989 end-page: 123 ident: bib36 article-title: On the role of brain mineralocorticoid (type I) and glucocorticoid (type II) receptors in neuroendocrine regulation publication-title: Neuroendocrinology contributor: fullname: de Kloet – volume: 1018 start-page: 323 year: 2004 end-page: 327 ident: bib23 article-title: Spatial performance and corticosteroid receptor status in the 21-day restraint stress paradigm publication-title: Ann. N. Y. Acad. Sci. contributor: fullname: Kittas – volume: 27 start-page: 2542 year: 2008 end-page: 2550 ident: bib34 article-title: Rapid changes in hippocampal CA1 pyramidal cell function via pre-as well as postsynaptic membrane mineralocorticoid receptors publication-title: Eur. J. Neurosci. contributor: fullname: Karst – volume: 104 start-page: 4688 year: 2007 end-page: 4693 ident: bib37 article-title: Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice publication-title: Proc. Natl. Acad. Sci. U. S. A contributor: fullname: Seasholtz – volume: 277 start-page: 45 year: 1999 end-page: 48 ident: bib46 article-title: Continuous blockade of brain mineralocorticoid receptors impairs spatial learning in rats publication-title: Neurosci. Lett. contributor: fullname: Seckl – volume: 106 start-page: 62 year: 1992 end-page: 71 ident: bib30 article-title: Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning publication-title: Behav. Neurosci. contributor: fullname: de Kloet – volume: 103 start-page: 195 year: 2006 end-page: 200 ident: bib2 article-title: Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity publication-title: Proc. Natl. Acad. Sci. U. S. A contributor: fullname: Schutz – volume: 167 start-page: 257 year: 2008 end-page: 261 ident: bib6 article-title: Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice publication-title: Prog. Brain Res. contributor: fullname: Oitzl – volume: 17 start-page: 128 year: 2003 end-page: 136 ident: bib29 article-title: Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice publication-title: Eur. J. Neurosci. contributor: fullname: Holsboer – start-page: 1 year: 2007 end-page: 8 ident: bib4 article-title: Emotion and cognition in high and low stress sensitive mouse strains: a combined neuroendocrine and behavioral study in BALB/c and C57BL/6J mice publication-title: Front. Behav. Neurosci. contributor: fullname: Oitzl – volume: 8 start-page: 794 year: 1996 end-page: 800 ident: bib38 article-title: Novelty-related rapid locomotor effects of corticosterone in rats publication-title: Eur. J. Neurosci contributor: fullname: Guaza – volume: 104 start-page: 4688 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib37 article-title: Mineralocorticoid receptor overexpression in forebrain decreases anxiety-like behavior and alters the stress response in mice publication-title: Proc. Natl. Acad. Sci. U. S. A doi: 10.1073/pnas.0606067104 contributor: fullname: Rozeboom – volume: 10 start-page: 152 year: 2006 ident: 10.1016/j.yhbeh.2009.05.003_bib19 article-title: Learning under stress: how does it work? publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2006.02.002 contributor: fullname: Joels – volume: 25 start-page: 973 year: 2004 ident: 10.1016/j.yhbeh.2009.05.003_bib11 article-title: Rapid glucocorticoid mediation of suppressed testosterone biosynthesis in male mice subjected to immobilization stress publication-title: J. Androl doi: 10.1002/j.1939-4640.2004.tb03170.x contributor: fullname: Dong – volume: 1018 start-page: 323 year: 2004 ident: 10.1016/j.yhbeh.2009.05.003_bib23 article-title: Spatial performance and corticosteroid receptor status in the 21-day restraint stress paradigm publication-title: Ann. N. Y. Acad. Sci. doi: 10.1196/annals.1296.039 contributor: fullname: Kitraki – volume: 29 start-page: 618 year: 2004 ident: 10.1016/j.yhbeh.2009.05.003_bib28 article-title: Genomic and non-genomic effects of glucocorticoids on aggressive behavior in male rats publication-title: Psychoneuroendocrinology doi: 10.1016/S0306-4530(03)00090-8 contributor: fullname: Mikics – volume: 167 start-page: 257 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib6 article-title: Strain specific fear behaviour and glucocorticoid response to aversive events: modelling PTSD in mice publication-title: Prog. Brain Res. doi: 10.1016/S0079-6123(07)67019-8 contributor: fullname: Brinks – volume: 17 start-page: 128 year: 2003 ident: 10.1016/j.yhbeh.2009.05.003_bib29 article-title: Impact of high and low anxiety on cognitive performance in a modified hole board test in C57BL/6 and DBA/2 mice publication-title: Eur. J. Neurosci. doi: 10.1046/j.1460-9568.2003.02436.x contributor: fullname: Ohl – volume: 22 start-page: 1323 year: 1997 ident: 10.1016/j.yhbeh.2009.05.003_bib42 article-title: Facilitation of feedback inhibition through blockade of glucocorticoid receptors in the hippocampus publication-title: Neurochem. Res. doi: 10.1023/A:1022010904600 contributor: fullname: van Haarst – volume: 8 start-page: 794 year: 1996 ident: 10.1016/j.yhbeh.2009.05.003_bib38 article-title: Novelty-related rapid locomotor effects of corticosterone in rats publication-title: Eur. J. Neurosci doi: 10.1111/j.1460-9568.1996.tb01264.x contributor: fullname: Sandi – start-page: 1 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib4 article-title: Emotion and cognition in high and low stress sensitive mouse strains: a combined neuroendocrine and behavioral study in BALB/c and C57BL/6J mice publication-title: Front. Behav. Neurosci. contributor: fullname: Brinks – volume: 65 start-page: 209 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib27 article-title: The effects of stress and stress hormones on human cognition: implications for the field of brain and cognition publication-title: Brain Cogn. doi: 10.1016/j.bandc.2007.02.007 contributor: fullname: Lupien – volume: 3 start-page: 168 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib10 article-title: Therapy Insight: is there an imbalanced response of mineralocorticoid and glucocorticoid receptors in depression? publication-title: Nat. Clin. Pract. Endocrinol. Metab. doi: 10.1038/ncpendmet0403 contributor: fullname: de Kloet – volume: 6 start-page: 463 year: 2005 ident: 10.1016/j.yhbeh.2009.05.003_bib9 article-title: Stress and the brain: from adaptation to disease publication-title: Nat. Rev. Neurosci. doi: 10.1038/nrn1683 contributor: fullname: de Kloet – volume: 34 start-page: 372 year: 2000 ident: 10.1016/j.yhbeh.2009.05.003_bib15 article-title: A refined method for sequential blood sampling by tail incision in rats publication-title: Lab. Anim doi: 10.1258/002367700780387714 contributor: fullname: Fluttert – volume: 73 start-page: 811 year: 2001 ident: 10.1016/j.yhbeh.2009.05.003_bib16 article-title: Mice with targeted mutations of glucocorticoid and mineralocorticoid receptors: models for depression and anxiety? publication-title: Physiol. Behav. doi: 10.1016/S0031-9384(01)00518-2 contributor: fullname: Gass – volume: 20 start-page: 655 year: 1995 ident: 10.1016/j.yhbeh.2009.05.003_bib32 article-title: Corticosterone, brain mineralocorticoid receptors (MRs) and the activity of the hypothalamic–pituitary–adrenal (HPA) axis: the Lewis rat as an example of increased central MR capacity and a hyporesponsive HPA axis publication-title: Psychoneuroendocrinology doi: 10.1016/0306-4530(95)00003-7 contributor: fullname: Oitzl – volume: 1007 start-page: 379 year: 2003 ident: 10.1016/j.yhbeh.2009.05.003_bib41 article-title: Corticosteroid receptor transgenic mice: models for depression? publication-title: Ann. N. Y. Acad. Sci. doi: 10.1196/annals.1286.037 contributor: fullname: Urani – volume: 103 start-page: 195 year: 2006 ident: 10.1016/j.yhbeh.2009.05.003_bib2 article-title: Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity publication-title: Proc. Natl. Acad. Sci. U. S. A doi: 10.1073/pnas.0503878102 contributor: fullname: Berger – volume: 7 start-page: 143 year: 2004 ident: 10.1016/j.yhbeh.2009.05.003_bib45 article-title: Decreased expression of mineralocorticoid receptor mRNA in the prefrontal cortex in schizophrenia and bipolar disorder publication-title: Int. J. Neuropsychopharmacol. doi: 10.1017/S1461145703004000 contributor: fullname: Xing – volume: 31 start-page: 620 year: 2006 ident: 10.1016/j.yhbeh.2009.05.003_bib43 article-title: Glucocorticoid receptor gene-based SNP analysis in patients with recurrent major depression publication-title: Neuropsychopharmacology doi: 10.1038/sj.npp.1300898 contributor: fullname: van West – volume: 294 start-page: E1011 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib1 article-title: Corticosteroids mediate fast feedback of the rat hypothalamic–pituitary–adrenal axis via the mineralocorticoid receptor publication-title: Am. J. Physiol. Endocrinol. Metab. doi: 10.1152/ajpendo.00721.2007 contributor: fullname: Atkinson – volume: 27 start-page: 2542 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib34 article-title: Rapid changes in hippocampal CA1 pyramidal cell function via pre-as well as postsynaptic membrane mineralocorticoid receptors publication-title: Eur. J. Neurosci. doi: 10.1111/j.1460-9568.2008.06220.x contributor: fullname: Olijslagers – volume: 25 start-page: 1832 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib26 article-title: Forebrain mineralocorticoid receptor overexpression enhances memory, reduces anxiety and attenuates neuronal loss in cerebral ischaemia publication-title: Eur. J. Neurosci. doi: 10.1111/j.1460-9568.2007.05427.x contributor: fullname: Lai – volume: 216 start-page: 375 issue: 2 year: 2009 ident: 10.1016/j.yhbeh.2009.05.003_bib7 article-title: Corticosterone facilitates extinction of fear memory in BALB/c mice but strengthens cue related fear in C57BL/6 mice publication-title: Exp. Neurol. doi: 10.1016/j.expneurol.2008.12.011 contributor: fullname: Brinks – volume: 288 start-page: E1082 year: 2005 ident: 10.1016/j.yhbeh.2009.05.003_bib35 article-title: Disruption of mineralocorticoid receptor function increases corticosterone responding to a mild, but not moderate, psychological stressor publication-title: Am. J. Physiol. Endocrinol. Metab. doi: 10.1152/ajpendo.00521.2004 contributor: fullname: Pace – volume: 274 start-page: 239 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib18 article-title: Spatial ability is impaired and hippocampal mineralocorticoid receptor mRNA expression reduced in zebra finches (Taeniopygia guttata) selected for acute high corticosterone response to stress publication-title: Proc. Biol. Sci. doi: 10.1098/rspb.2006.3704 contributor: fullname: Hodgson – volume: 11 start-page: 413 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib39 article-title: Neural correlates of emotion regulation in psychopathology publication-title: Trends Cogn. Sci. doi: 10.1016/j.tics.2007.08.006 contributor: fullname: Taylor – volume: 583 start-page: 372 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib22 article-title: Mineralocorticoid receptors in brain, in health and disease: possibilities for new pharmacotherapy publication-title: Eur. J. Pharmacol. doi: 10.1016/j.ejphar.2007.07.072 contributor: fullname: Kellner – volume: 20 start-page: 385 year: 1995 ident: 10.1016/j.yhbeh.2009.05.003_bib25 article-title: Anxiolytic-like effects of selective mineralocorticoid and glucocorticoid antagonists on fear-enhanced behavior in the elevated plus-maze publication-title: Psychoneuroendocrinology doi: 10.1016/0306-4530(94)00069-7 contributor: fullname: Korte – volume: 18 start-page: 1103 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib14 article-title: Overexpression of mineralocorticoid and transdominant glucocorticoid receptor blocks the impairing effects of glucocorticoids on memory publication-title: Hippocampus doi: 10.1002/hipo.20467 contributor: fullname: Ferguson – volume: 20 start-page: 6983 year: 2000 ident: 10.1016/j.yhbeh.2009.05.003_bib20 article-title: Neurobiological correlates of individual differences in novelty-seeking behavior in the rat: differential expression of stress-related molecules publication-title: J. Neurosci. doi: 10.1523/JNEUROSCI.20-18-06983.2000 contributor: fullname: Kabbaj – volume: 22 start-page: 422 year: 1999 ident: 10.1016/j.yhbeh.2009.05.003_bib8 article-title: Stress and cognition: are corticosteroids good or bad guys? publication-title: Trends Neurosci. doi: 10.1016/S0166-2236(99)01438-1 contributor: fullname: de Kloet – volume: 98 start-page: 12790 year: 2001 ident: 10.1016/j.yhbeh.2009.05.003_bib33 article-title: . Point mutation in the mouse glucocorticoid receptor preventing DNA binding impairs spatial memory publication-title: Proc. Natl. Acad. Sci. U. S. A doi: 10.1073/pnas.231313998 contributor: fullname: Oitzl – volume: 62 start-page: 33 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib40 article-title: Persistent disruption of a traumatic memory by postretrieval inactivation of glucocorticoid receptors in the amygdala publication-title: Biol. Psychiatry doi: 10.1016/j.biopsych.2006.09.009 contributor: fullname: Tronel – volume: 164 start-page: 197 year: 2005 ident: 10.1016/j.yhbeh.2009.05.003_bib12 article-title: Glucocorticoid receptor antagonism in the basolateral amygdala and ventral hippocampus interferes with long-term memory of contextual fear publication-title: Behav. Brain Res. doi: 10.1016/j.bbr.2005.06.020 contributor: fullname: Donley – volume: 25 start-page: 117 year: 2001 ident: 10.1016/j.yhbeh.2009.05.003_bib24 article-title: Corticosteroids in relation to fear, anxiety and psychopathology publication-title: Neurosci. Biobehav. Rev. doi: 10.1016/S0149-7634(01)00002-1 contributor: fullname: Korte – volume: 821 start-page: 33 year: 1999 ident: 10.1016/j.yhbeh.2009.05.003_bib13 article-title: Glucocorticoid receptor antagonists in the hippocampus modify the negative feedback following neural stimuli publication-title: Brain Res. doi: 10.1016/S0006-8993(99)01054-9 contributor: fullname: Feldman – volume: 187 start-page: 41 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib44 article-title: Enriched environment prevents chronic stress-induced spatial learning and memory deficits publication-title: Behav. Brain Res. doi: 10.1016/j.bbr.2007.08.025 contributor: fullname: Wright – volume: 2007 start-page: 90163 year: 2007 ident: 10.1016/j.yhbeh.2009.05.003_bib5 article-title: Differential MR/GR activation in mice results in emotional states beneficial or impairing for cognition publication-title: Neural Plast. doi: 10.1155/2007/90163 contributor: fullname: Brinks – volume: 86 start-page: 150 year: 2006 ident: 10.1016/j.yhbeh.2009.05.003_bib17 article-title: Individual differences in anxiety trait are related to spatial learning abilities and hippocampal expression of mineralocorticoid receptors publication-title: Neurobiol. Learn. Mem. doi: 10.1016/j.nlm.2006.02.001 contributor: fullname: Herrero – volume: 6 start-page: 1072 year: 1994 ident: 10.1016/j.yhbeh.2009.05.003_bib31 article-title: The effect of corticosterone on reactivity to spatial novelty is mediated by central mineralocorticosteroid receptors publication-title: Eur. J. Neurosci. doi: 10.1111/j.1460-9568.1994.tb00604.x contributor: fullname: Oitzl – volume: 277 start-page: 45 year: 1999 ident: 10.1016/j.yhbeh.2009.05.003_bib46 article-title: Continuous blockade of brain mineralocorticoid receptors impairs spatial learning in rats publication-title: Neurosci. Lett. doi: 10.1016/S0304-3940(99)00858-7 contributor: fullname: Yau – volume: 22 start-page: 105 year: 2008 ident: 10.1016/j.yhbeh.2009.05.003_bib3 article-title: Stressor-specific alterations in corticosterone and immune responses in mice publication-title: Brain Behav. Immunol. doi: 10.1016/j.bbi.2007.07.012 contributor: fullname: Bowers – volume: 106 start-page: 62 year: 1992 ident: 10.1016/j.yhbeh.2009.05.003_bib30 article-title: Selective corticosteroid antagonists modulate specific aspects of spatial orientation learning publication-title: Behav. Neurosci. doi: 10.1037/0735-7044.106.1.62 contributor: fullname: Oitzl – volume: 102 start-page: 19204 year: 2005 ident: 10.1016/j.yhbeh.2009.05.003_bib21 article-title: Mineralocorticoid receptors are indispensable for nongenomic modulation of hippocampal glutamate transmission by corticosterone publication-title: Proc. Natl. Acad. Sci. U. S. A doi: 10.1073/pnas.0507572102 contributor: fullname: Karst – volume: 50 start-page: 117 year: 1989 ident: 10.1016/j.yhbeh.2009.05.003_bib36 article-title: On the role of brain mineralocorticoid (type I) and glucocorticoid (type II) receptors in neuroendocrine regulation publication-title: Neuroendocrinology doi: 10.1159/000125210 contributor: fullname: Ratka |
SSID | ssj0011544 |
Score | 2.2114387 |
Snippet | The stress hormone corticosterone acts via two receptor types in the brain: the mineralocorticoid (MR) and the glucocorticoid receptor (GR). Both receptors are... |
SourceID | proquest crossref pubmed pascalfrancis elsevier |
SourceType | Aggregation Database Index Database Publisher |
StartPage | 232 |
SubjectTerms | Animal behavior Animals Behavioral psychophysiology Biological and medical sciences Cognition - physiology Conditioning, Classical - physiology Corticosterone - blood Cues Emotion Emotions - physiology Environment Fear - physiology Fear conditioning Female Forebrain Freezing Reaction, Cataleptic Fundamental and applied biological sciences. Psychology Genes Hormones Hormones and behavior Memory - physiology Mice Mice, Inbred C57BL Mice, Transgenic Mineralocorticoid receptor Motor Activity Neuropsychological Tests Psychology. Psychoanalysis. Psychiatry Psychology. Psychophysiology Receptors, Mineralocorticoid - genetics Receptors, Mineralocorticoid - metabolism Restraint, Physical Rodents Stress Stress, Psychological Unconditioned behavior |
Title | Mineralocorticoid receptors in control of emotional arousal and fear memory |
URI | https://dx.doi.org/10.1016/j.yhbeh.2009.05.003 https://www.ncbi.nlm.nih.gov/pubmed/19447109 https://www.proquest.com/docview/194879614/abstract/ https://search.proquest.com/docview/20143917 https://search.proquest.com/docview/67524154 |
Volume | 56 |
hasFullText | 1 |
inHoldings | 1 |
isFullTextHit | |
isPrint | |
link | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV3db9MwED9tnYSQEIKNjzIofkA8ERYnthc_VhVTYWxCiEl9i5zY1jJpSbV2D33hb-fOcYr2UB54ipTEcXw-n-98v7sD-CBtapxWdHKvfSKy1CRGy9NEiboyUhjvq4DyvVTzK_FtIRd7MBtiYQhWGWV_L9ODtI53TiI1T5ZNQzG-nNKtLVId_Dv5PhzgdiTECA6mX8_nl1tnAiWc6QVykVCDIflQgHltrit3HfNW0vFKvmuDerI0KySb7-td7FZIw8Z09gyeRo2STfuffg57rj2Eo2mL1vTthn1kAeMZDs8P4dFFdKUfwflFExJOd2h-YsuusQwJ4ZZUfYc1LYsYdtZ55vpSP9iJuevuV3RtLfO4RtgtAXU3L-Dq7Muv2TyJlRWSGhWsdWK4ykSeZiZzKZooFVcUrsMLaymXTV5VttaV9lxwX-BkFVwaWZjCoa7G09yq_CWM2q51r4FldVY7WddKm1R4q03tTGGcdMqi7NJyDJ8GcpbLPoFGOSDLbspAfSqFqctUUp7SMaiB5OUDPihRxP-74eTBBG07Ix2G3NZjOB5mrIzrdFVyjQabRhVlDO-3T3GBkdfEtA5pin1wik4-3f0G2lykB-E3XvWM8HegWggCu77531Edw-PefUWIw7cwWt_du3eoBa2rCex__s0nyOuzn99_TCLP_wGTOwe6 |
link.rule.ids | 315,786,790,4521,24144,27957,27958,45620,45714 |
linkProvider | Elsevier |
linkToHtml | http://utb.summon.serialssolutions.com/2.0.0/link/0/eLvHCXMwnV09b9swED2kDtAWKIo2aVI3XxyKThUiSqQsjkbQwKljTwngjaAkElGASEbsDP73vaMoFxncoZMASRTFI3l8x3u8A_guq9hYldHOvXKRSGITGSVHUSbKwkhhnCs8y3eeTe7F74Vc7MFVfxaGaJVB93c63WvrcOcySPNyWdd0xpdTuLVFrLx_J30D-0KOuBjA_vhmOplvnQkUcKZTyHlEBfrgQ57mtXko7EOIW0nbK-muBerD0qxQbK7Ld7EbkPqF6foTfAyIko27n_4Me7Y5gMNxg9b004b9YJ7j6TfPD-DtLLjSD2E6q33A6RbNTyzZ1hVDQdglZd9hdcMCh521jtku1Q9WYp7blxVdm4o5nCPsiYi6my9wf_3r7moShcwKUYkAax0ZniUijROT2BhNlIJndFyH51VFsWzSoqhKVSjHBXc5dlbOpZG5yS1iNR6nVZYewaBpG_sVWFImpZVlmSkTC1cpU1qTGyttVqHuUnIIP3tx6mUXQEP3zLJH7aVPqTCVjiXFKR1C1otcvxoHGlX8vwuev-qgbWWEYchtPYSTvsd0mKcrzRUabAohyhAutk9xgpHXxDQWZYp1cDqdPNr9BtpchIPwG8fdQPjbUCUEkV2__W-rLuDd5G52q29v5tMTeN-5soh9eAqD9fOLPUNEtC7Ow4j_A6wVCBc |
openUrl | ctx_ver=Z39.88-2004&ctx_enc=info%3Aofi%2Fenc%3AUTF-8&rfr_id=info%3Asid%2Fsummon.serialssolutions.com&rft_val_fmt=info%3Aofi%2Ffmt%3Akev%3Amtx%3Ajournal&rft.genre=article&rft.atitle=Mineralocorticoid+receptors+in+control+of+emotional+arousal+and+fear+memory&rft.jtitle=Hormones+and+behavior&rft.au=Brinks%2C+V&rft.au=Berger%2C+S&rft.au=Gass%2C+P&rft.au=de+Kloet%2C+E+R&rft.date=2009-08-01&rft.eissn=1095-6867&rft.volume=56&rft.issue=2&rft.spage=232&rft_id=info:doi/10.1016%2Fj.yhbeh.2009.05.003&rft_id=info%3Apmid%2F19447109&rft.externalDocID=19447109 |
thumbnail_l | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/lc.gif&issn=0018-506X&client=summon |
thumbnail_m | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/mc.gif&issn=0018-506X&client=summon |
thumbnail_s | http://covers-cdn.summon.serialssolutions.com/index.aspx?isbn=/sc.gif&issn=0018-506X&client=summon |