Exposure to Ambient Particulate Matter Is Associated With Accelerated Functional Decline in Idiopathic Pulmonary Fibrosis

• Published in: Chest Vol. 153; no. 5; p. 1221
• Main Authors: Winterbottom, Christopher J, Shah, Rupal J, Patterson, Karen C, Kreider, Maryl E, Panettieri, Jr, Reynold A, Rivera-Lebron, Belinda, Miller, Wallace T, Litzky, Leslie A, Penning, Trevor M, Heinlen, Krista, Jackson, Tara, Localio, A Russell, Christie, Jason D
• Format: Journal Article
• Language: English
• Published: United States 01.05.2018
• Subjects: air pollution; idiopathic pulmonary fibrosis; interstitial lung disease; environmental pollution; pulmonary fibrosis

Idiopathic pulmonary fibrosis (IPF), a progressive disease with an unknown pathogenesis, may be due in part to an abnormal response to injurious stimuli by alveolar epithelial cells. Air pollution and particulate inhalation of matter evoke a wide variety of pulmonary and systemic inflammatory diseas...