Viral protein targeting to the cortical endoplasmic reticulum is required for cell–cell spreading in plants

• Published in: The Journal of cell biology Vol. 193; no. 3; pp. 521 - 535
• Main Authors: Wu, Chih-Hang, Lee, Shu-Chuan, Wang, Chao-Wen
• Format: Journal Article
• Language: English
• Published: United States Rockefeller University Press 02.05.2011; The Rockefeller University Press
• Subjects: Amino Acid Sequence; Cell Membrane - metabolism; Cells; Cellular biology; Chromatography, Gel; Cytoplasm - metabolism; Endoplasmic Reticulum - metabolism; Flowers & plants; Gene expression; Membranes; Microscopy, Fluorescence - methods; Models, Biological; Molecular Sequence Data; Mutation; Plants - metabolism; Plants - virology; Potexvirus; Potexvirus - genetics; Protein Transport; Proteins; Sequence Homology, Amino Acid; Signal Transduction; Viral Proteins - metabolism; Yeasts

Many plant RNA viruses use their nonstructural proteins to target and move through the cortical endoplasmic reticulum (ER) tubules within the plant intercellular junction for cell-to-cell spreading. Most of these proteins, including the triple-gene-block 3 protein (TGBp3) of Potexvirus, are ER membr...