In-line filtration in very preterm neonates: a randomized controlled trial

• Published in: Scientific reports Vol. 10; no. 1; p. 5003
• Main Authors: Virlouvet, Anne-Laure, Pansiot, Julien, Toumazi, Artemis, Colella, Marina, Capewell, Andreas, Guerriero, Emilie, Storme, Thomas, Rioualen, Stéphane, Bourmaud, Aurélie, Biran, Valérie, Baud, Olivier
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 19.03.2020; Nature Publishing Group
• Subjects: 692/308/3187; 692/420/256; 692/499; 692/53/2421; 692/53/2422; Clinical trials; Critical Illness - therapy; Cytokines; Cytokines - blood; Filtration; Human health and pathology; Humanities and Social Sciences; Humans; Infant, Extremely Premature; Infants; Inflammation; Inflammation Mediators - blood; Infusions, Intravenous - adverse effects; Infusions, Intravenous - instrumentation; Infusions, Intravenous - methods; Life Sciences; multidisciplinary; Neonates; Newborn babies; Pediatrics; Prognosis; Santé publique et épidémiologie; Science; Science (multidisciplinary); Time Factors; Vascular Access Devices

In-line filtration is increasingly used in critically-ill infants but its benefits, by preventing micro-particle infusion in very preterm neonates, remain to be demonstrated. We conducted a randomized controlled trial among very preterm infants allocated to receive either in-line filtration of all t...