Multiplex PCR Pathogen Detection in Acute Gastroenteritis Among Hospitalized US Children Compared With Healthy Controls During 2011–2016 in the Post–Rotavirus Vaccine Era

• Published in: Open forum infectious diseases Vol. 8; no. 12; p. ofab592
• Main Authors: Harrison, Christopher J, Hassan, Ferdaus, Lee, Brian, Boom, Julie, Sahni, Leila C, Johnson, Coreen, Dunn, James, Payne, Daniel C, Wikswo, Mary E, Parashar, Umesh, Selvarangan, Rangaraj
• Format: Journal Article
• Language: English
• Published: US Oxford University Press 01.12.2021
• Subjects: Age; Gastroenteritis; Hospitalization; Major; Norovirus; Pathogens; Rotavirus; Salmonella; Surveillance; Vaccines; Viruses; United States > US; pediatric gastroenteritis; Vesikari; multiplex; norovirus; rotavirus

Abstract Background Despite vaccine-induced decreases in US rotavirus (RV) disease, acute gastroenteritis (AGE) remains relatively common. We evaluated AGE pathogen distribution in hospitalized US children in the post–RV vaccine era. Methods From December 2011 to June 2016, the New Vaccine Surveilla...