Adaptive response of neonatal sepsis-derived Group B Streptococcus to bilirubin

• Published in: Scientific reports Vol. 8; no. 1; pp. 6470 - 10
• Main Authors: Hansen, Richard, Gibson, Sophie, De paiva Alves, Eduardo, Goddard, Mark, MacLaren, Andrew, Karcher, Anne Marie, Berry, Susan, Collie-Duguid, Elaina S. R., El-Omar, Emad, Munro, Mike, Hold, Georgina L.
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 24.04.2018; Nature Publishing Group
• Subjects: 631/326/107; 692/308/2778; 692/308/3187; 82; 82/29; 82/81; Age; Antioxidants; Bilirubin; Carbohydrate metabolism; Endotoxemia; Gene expression; Humanities and Social Sciences; Hyperbilirubinemia; Jaundice; multidisciplinary; Neonates; Physiology; Proteomics; Science; Science (multidisciplinary); Sepsis; Shock; Streptococcus; Streptococcus infections

Hyperbilirubinemia is so common in newborns as to be termed physiological. The most common bacteria involved in early-onset neonatal sepsis are Streptococcus agalactiae , commonly called Group B Streptococcus (GBS). Whilst previous studies show bilirubin has antioxidant properties and is beneficial...