Environmental fluoride exposure and implications on potential pediatric kidney health risks: an approach with urinary biomarkers

• Published in: Pediatric nephrology (Berlin, West) Vol. 39; no. 5; pp. 1469 - 1480
• Main Authors: Gunasekara, T. D. K. S. C., De Silva, P. Mangala C. S., Chandana, E. P. S., Jayasinghe, Sudheera, Herath, Chula, Siribaddana, Sisira, Jayasundara, Nishad
• Format: Journal Article
• Language: English
• Published: Berlin/Heidelberg Springer Berlin Heidelberg 01.05.2024; Springer; Springer Nature B.V
• Subjects: Biomarkers; Child; Children; Creatinine; Diagnosis; Diseases; Environmental aspects; Fluorides; Fluorides - adverse effects; Gelatinase; Geographical variations; Health aspects; Health risks; Humans; Kidney; Kidney diseases; Kidneys; Leukocytes (neutrophilic); Lipocalin; Lipocalin-2; Measurement; Medicine; Medicine & Public Health; Nephrology; Original Article; Pediatrics; Population studies; Renal Insufficiency, Chronic - epidemiology; Risk factors; Urine; Urology; Sri Lanka; Biomarkers; Fluoride; Sri Lanka; Kidney injury; Pediatric

Background Environmental fluoride exposure at elevated levels is potentially linked to kidney injury, and may contribute to chronic kidney disease of uncertain etiology (CKDu) as a risk factor. However, this link remains unclear, and examining the risk of kidney damage from early life fluoride expos...