Quantification of Arterial and Venous Morphologic Markers in Pulmonary Arterial Hypertension Using CT Imaging

• Published in: Chest Vol. 160; no. 6; pp. 2220 - 2231
• Main Authors: Rahaghi, Farbod N., Nardelli, Pietro, Harder, Eileen, Singh, Inderjit, Sánchez-Ferrero, Gonzalo Vegas, Ross, James C., San José Estépar, Rubén, Ash, Samuel Y., Hunsaker, Andetta R., Maron, Bradley A., Leopold, Jane A., Waxman, Aaron B., San José Estépar, Raúl, Washko, George R.
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2021; American College of Chest Physicians
• Subjects: Adult; Aged; arterial; CT imaging; exercise pulmonary hypertension; Female; Humans; Male; Middle Aged; pulmonary arterial hypertension; Pulmonary Arterial Hypertension - diagnostic imaging; Pulmonary Arterial Hypertension - physiopathology; Pulmonary Artery - diagnostic imaging; Pulmonary Artery - physiopathology; Pulmonary Vascular: Original Research; Pulmonary Veins - diagnostic imaging; Pulmonary Veins - physiopathology; Respiratory Function Tests; Retrospective Studies; Tomography, X-Ray Computed; tortuosity; venous; venous; CT imaging; PAH; tortuosity; arterial; ePH; exercise pulmonary hypertension; pulmonary arterial hypertension

Pulmonary hypertension is a heterogeneous disease, and a significant portion of patients at risk for it have CT imaging available. Advanced automated processing techniques could be leveraged for early detection, screening, and development of quantitative phenotypes. Pruning and vascular tortuosity h...