Infant Colic Represents Gut Inflammation and Dysbiosis

• Published in: The Journal of pediatrics Vol. 203; pp. 55 - 61.e3
• Main Authors: Rhoads, J. Marc, Collins, James, Fatheree, Nicole Y., Hashmi, S. Shahrukh, Taylor, Christopher M., Luo, Meng, Hoang, Thomas K., Gleason, Wallace A., Van Arsdall, Melissa R., Navarro, Fernando, Liu, Yuying
• Format: Journal Article
• Language: English
• Published: United States Elsevier Inc 01.12.2018
• Subjects: Acinetobacter - isolation & purification; Breast Feeding; calprotectin; Case-Control Studies; Colic - complications; crying; Dysbiosis - diagnosis; Feces - chemistry; Feces - microbiology; Female; functional bowel disorder; Gastrointestinal Microbiome; Humans; Infant; Infant Formula; Infant, Newborn; Inflammation - diagnosis; intestinal inflammation; Lactobacillus - isolation & purification; Leukocyte L1 Antigen Complex - analysis; Male; microbiota; newborn; microbiota; newborn; intestinal inflammation; functional bowel disorder; crying; calprotectin

To dissect potential confounding effects of breast milk and formula feeding on crying + fussing, fecal calprotectin, and gut microbiota in babies with colic. We hypothesized that infant colic is associated with gut inflammation linked to intestinal dysbiosis. A nested case-control design of 3 of our...