Detoxification mechanisms involved in ivermectin resistance in the cattle tick, Rhipicephalus (Boophilus) microplus

• Published in: Scientific reports Vol. 8; no. 1; pp. 12401 - 10
• Main Authors: Le Gall, Valeria Lis, Klafke, Guilherme Marcondes, Torres, Tatiana Teixeira
• Format: Journal Article
• Language: English
• Published: London Nature Publishing Group UK 17.08.2018; Nature Publishing Group
• Subjects: 631/326/417/2552; 631/45; 9/10; Bioassays; Cattle; Cytochrome; Cytochrome P450; Detoxification; Economic impact; Ectoparasites; Glutathione transferase; Humanities and Social Sciences; Inhibitors; Ivermectin; multidisciplinary; Phenotypes; Rhipicephalus microplus; Science; Science (multidisciplinary)

The cattle tick Rhipicephalus microplus is one of the most important ectoparasites with great sanitary and economic impact for cattle rearing worldwide. Ivermectin is commonly used to control tick populations, but its use over the last 30 years has led to the development of resistant populations of...