Atrial Fibrillation Ablation Outcome Is Predicted by Left Atrial Remodeling on MRI

• Published in: Circulation. Arrhythmia and electrophysiology Vol. 7; no. 1; pp. 23 - 30
• Main Authors: McGann, Christopher, Akoum, Nazem, Patel, Amit, Kholmovski, Eugene, Revelo, Patricia, Damal, Kavitha, Wilson, Brent, Cates, Josh, Harrison, Alexis, Ranjan, Ravi, Burgon, Nathan S., Greene, Tom, Kim, Dan, DiBella, Edward V.R., Parker, Dennis, MacLeod, Rob S., Marrouche, Nassir F.
• Format: Journal Article
• Language: English
• Published: United States American Heart Association, Inc 01.02.2014
• Subjects: Adult; Aged; Atrial Fibrillation - diagnosis; Atrial Fibrillation - physiopathology; Atrial Fibrillation - surgery; Atrial Function, Left; Atrial Remodeling; Biopsy; Case-Control Studies; Catheter Ablation - adverse effects; Chi-Square Distribution; Contrast Media; Female; Fibrosis; Heart Atria - pathology; Heart Atria - physiopathology; Heart Atria - surgery; Humans; Kaplan-Meier Estimate; Magnetic Resonance Imaging; Male; Meglumine - analogs & derivatives; Middle Aged; Multivariate Analysis; Organometallic Compounds; Patient Selection; Predictive Value of Tests; Proportional Hazards Models; Recurrence; Risk Factors; Treatment Outcome; atrial remodeling; magnetic resonance imaging; catheter ablation

BACKGROUND—Although catheter ablation therapy for atrial fibrillation (AF) is becoming more common, results vary widely, and patient selection criteria remain poorly defined. We hypothesized that late gadolinium enhancement MRI (LGE-MRI) can identify left atrial (LA) wall structural remodeling (SRM)...