Ascertainment of iron deficiency and depletion in blood donors through screening questions for pica and restless legs syndrome

• Published in: Transfusion (Philadelphia, Pa.) Vol. 53; no. 8; pp. 1637 - 1644
• Main Authors: Bryant, Barbara J., Yau, Yu Ying, Arceo, Sarah M., Hopkins, Julie A., Leitman, Susan F.
• Format: Journal Article
• Language: English
• Published: Hoboken, NJ Blackwell Publishing Ltd 01.08.2013; Wiley; Wiley Subscription Services, Inc
• Subjects: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anemia; Anemia, Iron-Deficiency - blood; Anemia, Iron-Deficiency - complications; Anemia, Iron-Deficiency - diagnosis; Anemia, Iron-Deficiency - drug therapy; Anemias. Hemoglobinopathies; Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy; Biological and medical sciences; Biomarkers - blood; Blood Donors; Blood. Blood and plasma substitutes. Blood products. Blood cells. Blood typing. Plasmapheresis. Apheresis; Case-Control Studies; Diseases of red blood cells; Drug Administration Schedule; Female; Ferritins - blood; Ferrous Compounds - therapeutic use; Hematinics - therapeutic use; Hematologic and hematopoietic diseases; Hemoglobins - metabolism; Humans; Iron; Logistic Models; Male; Mass Screening; Medical sciences; Metabolic diseases; Metals (hemochromatosis...); Middle Aged; Nervous system (semeiology, syndromes); Nervous system as a whole; Neurology; Other metabolic disorders; Pica - diagnosis; Pica - drug therapy; Pica - epidemiology; Pica - etiology; Prevalence; Prospective Studies; Restless legs syndrome; Restless Legs Syndrome - diagnosis; Restless Legs Syndrome - drug therapy; Restless Legs Syndrome - epidemiology; Restless Legs Syndrome - etiology; Surveys and Questionnaires; Transferrin - metabolism; Transfusions. Complications. Transfusion reactions. Cell and gene therapy; Young Adult; Human; Sensitivity disorder; Nervous system diseases; Transfusion; Iron deficiency anemia; Metabolic diseases; Hemopathy; Iron; Eating disorder; Medical screening; Inorganic element; Restless legs syndrome; Pica; Depletion; Neurological disorder; Sideropenia; Blood donor

Background Pica and restless legs syndrome (RLS) are associated with iron depletion and deficiency. The presence of pica and RLS was prospectively assessed in blood donors. Study Design and Methods During a 39‐month period, 1236 donors deferred for fingerstick hemoglobin (Hb) level of less than 12.5...